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  • Cell & Developmental Biology  (6)
  • LUNAR AND PLANETARY EXPLORATION  (6)
  • Life and Medical Sciences  (6)
  • 2000-2004
  • 1985-1989  (12)
  • 1925-1929
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  • 1
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    In:  Other Sources
    Publication Date: 2019-06-28
    Description: The D/H ratios and the C-13/C-12 ratios of acid-insoluble organic matter of 4 meteorites, Ochansk (H4), Plainview (H5), Gladstone (H6) and Odessa (IA), were measured. delta-D values for hydrogen extracted by stepwise combustion were negative, down to -280 deg/infinity. delta-C-13 values were also negative except in the case of the carbon coming off at the highest temperature steps for Plainview and Odessa meteorites. The concentrations of C-13-rich carbon were 3-5 orders of magnitude smaller than those found in Murchison meteorite, suggesting that relic grains of stellar condensates were mostly destroyed in the meteorites examined.
    Keywords: LUNAR AND PLANETARY EXPLORATION
    Type: Geophysical Research Letters (ISSN 0094-8276); 12; 73-76
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  • 2
    Publication Date: 2019-06-28
    Description: The thermal radio emission from Mercury at 3.3 mm and 28 mm was measured over a period of several years, and the results of a statistical analysis of the data are reported. The disk-average brightness temperature is reported as a function of longitude, and other periodicities are reported. The range of values of the thermophysical parameters is constrained by comparing the data with models.
    Keywords: LUNAR AND PLANETARY EXPLORATION
    Type: Icarus (ISSN 0019-1035); 62; 448-457
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  • 3
    Publication Date: 2019-07-12
    Description: Data are reported which, for the first time, permit the derivation of the full isotopic spectrum of s-process krypton with reasonable precision. It is shown that this s-Kr in a residue from the Murchison meteorite did not originate in one single s-process but rather is a mixture of contributions from stellar environments where the density of free neutrons was not the same. The astrophysical conditions under which this krypton was produced were distinct from those that have been invoked to explain the solar system s-process abundance. Similar to the C-13-rich carbon component in an aliquot of the same residue, the s-process Kr from different astrophysical sites has retained its identity during the accumulation and subsequent history of the meteorite.
    Keywords: LUNAR AND PLANETARY EXPLORATION
    Type: Nature (ISSN 0028-0836); 332; 700-702
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  • 4
    Publication Date: 2019-07-12
    Description: Isotopic fractionation processes in the formation of O3 by discharge (at 20 kV and 3 MHz) of O2 in a fused silica container at 77 K are investigated experimentally, with a focus on the effects of changes in the isotopic abundances in the predischarge O2, the O2 pressure, and the excitation energy on the isotope abundances in the postdischarge O2 and O3. The results are presented in extensive tables and graphs and characterized in detail, and good general agreement is found with data obtained using 60-kHz excitation (Yang and Epstein, 1987). It is shown that O-17 and O-18 enrichment of the residual O2 (when the predischarge gas is enriched) or of the O3 (when atmospheric isotope abundances are used) can occur independently of one another. It is inferred that the rate of anharmonic predissociation of vibrationally hot O3 depends on the symmetry and mass of the O3 molecules. The significance of the present findings for studies of anomalous oxygen isotope abundances in meteorites is indicated.
    Keywords: LUNAR AND PLANETARY EXPLORATION
    Type: Geochimica et Cosmochimica Acta (ISSN 0016-7037); 51; 2019-202
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  • 5
    Publication Date: 2019-07-12
    Description: Isotopic fractionation processes in the formation of O3 by 20-kV 60-kHz discharge of O2 in a fused silica container at 77 K are investigated experimentally, with a focus on the effects of changes in the isotopic composition of O2, the O2 pressure, the degree of O3 formation, and the discharge geometry on the isotope abundances in the postdischarge O2 and O3. The results are presented in tables and graphs and compared with the predictions of theoretical models involving vibrational anharmonicity and symmetry effects on O3 predissociation. In experiments using O2 enriched with O-17 and O-18, the heavy isotope is enriched in the residual O2 and not in the O3, whereas the opposite is true when atmospheric isotope abundances are used. It is inferred that the predissociation rate depends on the symmetry and mass of the O3 molecules and not on self-shielding or symmetry effects in the reactant O2. The potential value of the present findings for studies of anomalous isotope abundances in meteorites is indicated.
    Keywords: LUNAR AND PLANETARY EXPLORATION
    Type: Geochimica et Cosmochimica Acta (ISSN 0016-7037); 51; 2011-201
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  • 6
    Publication Date: 2019-07-12
    Description: The carbon isotopic composition of individual oxide grains from Murchison HF-HCl acid residue CFOc has been measured in the ion microprobe. Many grains contain carbon with large C-13 excesses ranging to 7000 per mil. In most cases the carbon is present as micron-sized subgrains. The association of silicon with the anomalous carbon points towards SiC as carrier. If this tentative identification is correct, then the SIC grains most likely originated in the circumstellar atmospheres of red giants. Oxide grains in which the O-18/O-16 ratio has also been measured show variable O-16 excesses which are not correlated with the C-13 excesses. This indicates that the sources of the anomalous carbon and oxygen isotopic compositions of the oxide grains are unrelated.
    Keywords: LUNAR AND PLANETARY EXPLORATION
    Type: Earth and Planetary Science Letters (ISSN 0012-821X); 84; 4 Au
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  • 7
    ISSN: 0730-2312
    Keywords: hypersensitivity ; granulomas ; skin ; athymic nude mice ; biomedical analysis ; angiotensin-converting enzyme ; eosinophil chemotactic factor ; Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Chemistry and Pharmacology , Medicine
    Notes: Activities of angiotensin-converting enzyme (ACE), other proteinases, and eosinophil chemotactic factor (ECF-G) are known to be elevated in hepatic hypersensitivity granulomas of thymus intact (nu/+) mice after Schistosoma mansoni infection. The enzyme activities also increase, but to a lesser degree in hepatic granulomas of athymic nude (nu/nu) mice, and ECF-G is not detectable. In this study isolated hepatic granulomas from nu/+ mice were grafted into the skin of uninfected nu/nu mice, and changes in those cellular functions were determined to examine whether the newly formed granulomas by recipient nu/nu cells acquire the functional activities as well as the histological appearance of nu/+ granulomas. ACE and ECF-G rapidly disappeared from grafted sites during the first 5 days, corresponding to loss of nu/+ cells from the graft. Reduction in activities of arylsulfatases, lysozyme, and acid phosphatase also occurred, but to a lesser extent. Recovery of ACE and ECF-G activities to the levels seen in nu/+ hepatic granulomas was observed by 14 days after grafting when nu/nu cells had accumulated in the grafts and formed new granulomas. Other enzymes increased to approximately half the levels seen in grafted donor granulomas. Circulating eosinophilia also increased. The findings indicate that nu/nu cells that accumulated in the skin grafts not only morphologically mimicked nu/+ type granulomas but also demonstrated nu/+ levels of cellular function. Analysis of skin granulomas developing in nu/+ mice after grafting of nu/+ hepatic granulomas showed the similar histology and enzymatic changes, whereas the skin sites inoculated with purified schistosome eggs alone caused neither significant histological changes nor elevation of ACE activity.
    Additional Material: 2 Ill.
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  • 8
    ISSN: 0362-2525
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Medicine
    Notes: The surface ultrastructure of the gill arches of the killifish, Fundulus heteroclitus, adapted to seawater or freshwater, was found to be similar to that reported for other euryhaline teleosts. Two rows of gill filaments (about 42 filaments per row) extended posterolaterally, and two rows of gill rakers (about 10 rakers per row) extended anteromedially from each arch. Leaf-like respiratory lamellae protruded along both sides of each filament, from its base to its apex. The distributions, sizes, and numbers of various surface cells and structures were also determined. All surfaces were covered by a mosaic of pavement cells, which measured about 7 × 4 μm and exhibited concentrically arranged surface ridges. Taste buds were especially prominent on the rakers and the pharyngeal surfaces of the first and second gill arches, but were often replaced by horny spines on the third and fourth gill arches. Apical crypts of chloride cells occurred mostly on the surfaces of the gill filaments adjacent to the afferent artery of the filament. In seawater adapted killifish, crypts resembled narrow, deep holes along the borders of adjacent pavement cells, had openings of about 2 μm2, and occurred at a frequency of about 1 per 70 μ2 of surface area. In freshwater fish, the crypts usually had larger openings (about 10 μ2), occurred less frequently (1 per 123 μ2), and exhibited many cellular projections in their interiors. Changes in crypt morphology may be related to the ion transport function of chloride cells.
    Additional Material: 13 Ill.
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  • 9
    Electronic Resource
    Electronic Resource
    New York, N.Y. : Wiley-Blackwell
    Journal of Cellular Biochemistry 32 (1986), S. 79-89 
    ISSN: 0730-2312
    Keywords: granulomatous inflammation ; murine elastase ; aldehyde-fuchsin-stained fibers ; granuloma ; Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Chemistry and Pharmacology , Medicine
    Notes: Elastases have been reported to be involved in various types of tissue injury. In this study we detected hydrolytic activities for [3H]-elastin and Suc-Ala-Ala-Ala-pNA (SLAPN) in hepatic granulomas which became elevated in parallel with enlargement of the granulomas and disappearance of aldehyde-fuchsin-stained filaments in the lesions of mice infected with Schistosoma mansoni. The elastase was partially purified by gel filtration followed by anion-exchange chromatography. This enzyme has a molecular weight of 20-25k and hydrolyzed denatured collagen (azocoll), Glu-Pro-Val-pNA, SLAPN, and [3H]-elastin. Optimal pH was 7-8.5. It is a serine proteinase and distinct in its inhibitor profile from murine peritoneal macrophage elastase, which has been reported by others. Digestion of elastic fibers in vessel walls and fine fibrils in newly developed granulomas by the granuloma elastase was histochemically identified with aldehyde-fuchsin stain. These results indicate that a serine proteinease functions as a major elastase in granulomatous tisssue remodeling and may account for the disappearance of elastic fibers and other elements of the matrix in fully developed granulomas.
    Additional Material: 6 Ill.
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  • 10
    Electronic Resource
    Electronic Resource
    New York, NY [u.a.] : Wiley-Blackwell
    Journal of Cellular Physiology 130 (1987), S. 336-343 
    ISSN: 0021-9541
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Medicine
    Notes: The characterization of the proliferation-associated nuclear antigen designated p105 in quiescent and proliferating lymphocytes is described. Through the use of novel flow cytometric and cell-sorting strategies the intracellular content of p105 was assessed in situ on a per cell basis. These analyses demonstrated the presence of multiple cellular subpopulations within the cell cycle differing significantly in p105 content. The data revealed that the flow cytometric quantitation of p105 levels may effectively discriminate cycling from noncycling cells. Immunogold electron microscopy revealed that the modulation of this interchromatin-associated antigen was correlated with a significant degree of nuclear restructuring. In conjunction with cell sorting, immunogold electron microscopy and immunoblot controls demonstrated that the cell-cycle-related modulation in p105 cannot be accounted for by increased cellular mass or antigen sequestration. The significance of these controls and of the potential role of p105 in cellular proliferation is discussed.
    Additional Material: 5 Ill.
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