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  • 1
    Electronic Resource
    Electronic Resource
    History and Significance of White Macules, Earliest Visible Sign of Tuberous Sclerosis (1991)
    Oxford, UK : Blackwell Publishing Ltd
    Annals of the New York Academy of Sciences 615 (1991), S. 0 
    Details
    ISSN: 1749-6632
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Natural Sciences in General
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1749-6632.1991.tb37745.x
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  • 2
    Electronic Resource
    Electronic Resource
    TGFβ Independently Regulates Invasiveness, Chemotaxis, and Proliferation of Human Breast Cancer Cells (1990)
    Oxford, UK : Blackwell Publishing Ltd
    Annals of the New York Academy of Sciences 593 (1990), S. 0 
    Details
    ISSN: 1749-6632
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Natural Sciences in General
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1749-6632.1990.tb16146.x
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  • 3
    Electronic Resource
    Electronic Resource
    Quantitative Cancer Risk Estimation for Formaldehyde (1990)
    Oxford, UK : Blackwell Publishing Ltd
    Risk analysis 10 (1990), S. 0 
    Details
    ISSN: 1539-6924
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Energy, Environment Protection, Nuclear Power Engineering
    Notes: Of primary concern are irreversible effects, such as cancer induction, that formaldehyde exposure could have on human health. Dose-response data from human exposure situations would provide the most solid foundation for risk assessment, avoiding problematic extrapolations from the health effects seen in nonhuman species. However, epidemiologic studies of human formaldehyde exposure have provided little definitive information regarding dose-response. Reliance must consequently be placed on laboratory animal evidence. An impressive array of data points to significantly nonlinear relationships between rodent tumor incidence and administered dose, and between target tissue dose and administered dose (the latter for both rodents and Rhesus monkeys) following exposure to formaldehyde by inhalation. Disproportionately less formaldehyde binds covalently to the DNA of nasal respiratory epithelium at low than at high airborne concentrations. Use of this internal measure of delivered dose in analyses of rodent bioassay nasal tumor response yields multistage model estimates of low-dose risk, both point and upper bound, that are lower than equivalent estimates based upon airborne formaldehyde concentration. In addition, risk estimates obtained for Rhesus monkeys appear at least 10-fold lower than corresponding estimates for identically exposed Fischer-344 rats.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1539-6924.1990.tb01023.x
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  • 4
    Electronic Resource
    Electronic Resource
    Confirmation of the Location of a Waardenburg Syndrome Type I Mutation on Human Chromosome 2q (1991)
    Oxford, UK : Blackwell Publishing Ltd
    Annals of the New York Academy of Sciences 630 (1991), S. 0 
    Details
    ISSN: 1749-6632
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Natural Sciences in General
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1749-6632.1991.tb19611.x
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  • 5
    Electronic Resource
    Electronic Resource
    RECOVERY OF ESCHERICHIA COLI O157:H7 FROM FIBER OPTIC WAVEGUIDES USED FOR RAPID BIOSENSOR DETECTION (2002)
    Oxford, UK : Blackwell Publishing Ltd
    Journal of rapid methods and automation in microbiology 10 (2002), S. 0 
    Details
    ISSN: 1745-4581
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Biology
    Notes: Consumption of ground beef has been implicated in the majority of outbreaks of disease from Escherichia coli O157:H7. There is a great need for rapid, sensitive, and specific microbial detection and isolation methods for the detection and recovery of pathogens such as E. coli O157:H7. Evanescent wave, fiber optic biosensors are an innovative, cutting-edge technology with the potential to meet such a need. Food pathogens such as E. coli O157:H7 can be detected in minutes using the biosensor assay rather than days using conventional methods. The biosensor assay is sensitive and presently has the ability to directly detect 102 CFU of E. coli O157:H7 in E. coli O157:H7-seeded PBS or ground beef. In this study, it was determined that once the pathogen had been positively identified, it could then be recovered by culturing the cells captured on the waveguide used in the biosensor assay. E. coli O157:H7-seeded PBS or ground beef samples were assayed using an evanescent wave, fiber optic biosensor. After a positive identification on the biosensor, the waveguide was added to modified LB medium supplemented with 10 μg/mL acriflavin (mLB) and incubated at 42C for a minimum of 4 h followed by selection on Rainbow O157 agar incubated 16 to 18 h at 37C. E. coli O157:H7 was confirmed using agglutination with E. coli O157:H7 antiserum. It was possible to recover E. coli O157:H7 colonies in E. coli O157:H7-seeded PBS or ground beef when 1 mL samples containing at least 2.0 × 103 CFU of E. coli O157:H7 had been injected into the biosensor. It took only 24 h to detect the target pathogen, recover the pathogen from the sample, and grow isolated colonies. This total time included sample preparation, detection, enrichment culture, and growth of cells to produce isolated colonies on a selective and differential medium. The identification of isolated colonies was then quickly confirmed using slide agglutination with the appropriate antiserum. This method significantly improved the speed of the confirmation of the presence of the pathogen and of the isolation of the pathogen, from 4 days using conventional methods to one day using the biosensor assay.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1745-4581.2002.tb00015.x
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  • 6
    Electronic Resource
    Electronic Resource
    A Comparison of Sorption Coefficients Determined by Batch, Column, and Box Methods on a Low Organic Carbon Aquifer Material (1991)
    Oxford, UK : Blackwell Publishing Ltd
    Ground water 29 (1991), S. 0 
    Details
    ISSN: 1745-6584
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Energy, Environment Protection, Nuclear Power Engineering , Geosciences
    Notes: Results of three independent experimental methods for determination of sorption coefficients were compared on sieved aquifer material samples from Columbus AFB, Columbus, Mississippi. These aquifer materials contained 〈0.1% organiccarbon, and sorption coefficients for naphthalene ranged from 0.06 to 0.20 I/kg. There was low correlation between organic carbon contents and sorption coefficients. Good agreement was found among sorption coefficients measured by batch, dynamic column, and dynamic box methods. Similarity of the coefficients was attributed to measured fast sorption kinetics and to linearity of isotherms observed for naphthalene sorption on Columbus aquifer material. Results indicate that channeling, wall and end effects, and particle loss were insignificant in the dynamic systems. Since laboratory sorption coefficient measurements were found impractical on whole sand-gravel aquifer samples, an equation is proposed to convert laboratory measured sorption coefficients on the separated sand (〈2 mm) fraction to sorption coefficients on wholesand-gravel aquifer materials.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1745-6584.1991.tb00578.x
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  • 7
    Electronic Resource
    Electronic Resource
    DISCUSSION OF “Delineation of a Discontinuous Aqui-tard with Vertical Electrical Soundings, San Bernardino Valley, Southern California,” by William P. Owen, Stephen K. Park, and Tien-Chang Lee, May-June 1991 issue, v. 29, no. 3, pp. 418-424 (1991)
    Oxford, UK : Blackwell Publishing Ltd
    Ground water 29 (1991), S. 0 
    Details
    ISSN: 1745-6584
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Energy, Environment Protection, Nuclear Power Engineering , Geosciences
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1745-6584.1991.tb00580.x
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  • 8
    Electronic Resource
    Electronic Resource
    Resources, Knowledge and Influence: The Organizational Effects of Interorganizational Collaboration* (2003)
    108 Cowley Road, Oxford OX4 1JF, UK : Blackwell Publishing Ltd
    Journal of management studies 40 (2003), S. 0 
    Details
    ISSN: 1467-6486
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Economics
    Notes: Inter-organizational collaboration has been linked to a range of important outcomes for collaborating organizations. The strategy literature emphasizes the way in which collaboration between organizations results in the sharing of critical resources and facilitates knowledge transfer. The learning literature argues that collaboration not only transfers existing knowledge among organizations, but also facilitates the creation of new knowledge and produce synergistic solutions. Finally, research on networks and interorganizational politics suggests that collaboration can help organizations achieve a more central and influential position in relation to other organizations. While these effects have been identified and discussed at some length, little attention has been paid to the relationship between them and the nature of the collaborations that produce them. In this paper, we present the results of a qualitative study that examines the relationship between the effects of interorganizational collaboration and the nature of the collaborations that produce them. Based on our study of the collaborative activities of a small, nongovernmental organization (NGO) in Palestine over a four-year period, we argue that two dimensions of collaboration – embeddedness and involvement – determine the potential of a collaboration to produce one or more of these effects.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/1467-6486.00342
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  • 9
    Electronic Resource
    Electronic Resource
    The role of the abaxial leaf surface waxes of Lolium spp. in resistance to Erysiphe graminis (1990)
    Oxford, UK : Blackwell Publishing Ltd
    Plant pathology 39 (1990), S. 0 
    Details
    ISSN: 1365-3059
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Agriculture, Forestry, Horticulture, Fishery, Domestic Science, Nutrition
    Notes: Field and glasshouse observations of Lolium spp. grasses indicated that the lower, abaxial, leaf surface was rarely infected by powdery mildew (Erysiphe graminis) even when the upper, adaxial, surface was densely colonized. Experiments showed that conidia of two strains of E. graminis, one from Lolium and one from Avena, germinated equally well on both surfaces of Lolium and Avena leaves, but that the subsequent growth and development of germlings was impaired on the lower surface of Lolium leaves, so that most formed only multiple short germ tubes or an abnormal long tube, and only c. 25% or fewer formed infection structures. This contributes to the apparent resistance of the lower Lolium leaf surface to powdery mildew and may help to explain why the disease is relatively unimportant in UK ryegrass crops, since infection structures develop at a high frequency on only 50% of the leaf area, i.e. the upper surface. Scanning electron microscopy showed that the epicuticular waxes on the lower Lolium leaf surface form amorphous sheets. This contrasts with the crystalline plate waxes seen on the upper surface of Lolium leaves and on both surfaces of oat leaves. However, when the lower Lolium leaf surface was washed with chloroform to remove epicuticular wax, normal germling and infection structure development was obtained on the wax-free surface. This suggests that the sheet waxes prevent the pathogen gaining access to features of the cuticular membrane which trigger normal germling development.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1365-3059.1990.tb02536.x
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  • 10
    Electronic Resource
    Electronic Resource
    Normal germling development by Erysiphe graminis on cereal leaves freed of epicuticular wax (1990)
    Oxford, UK : Blackwell Publishing Ltd
    Plant pathology 39 (1990), S. 0 
    Details
    ISSN: 1365-3059
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Agriculture, Forestry, Horticulture, Fishery, Domestic Science, Nutrition
    Notes: Experiments were conducted to test the hypothesis that recognition of the physical structure of epicuticular leaf waxes by Erysiphe graminis may be important to the development of normal germlings and the formation of functional appressoria. Comparisons of germination rates and characteristics of germling development by E. graminis f.sp. avenae, and in one experiment by f.sp. hordei, were made between intact cereal leaves and leaves from which the epicuticular waxes had been stripped away.Overall, fungal development was very similar on intact and wax-free leaves: although germination rates were slightly, but significantly, lower, and lengths of appressorial germ tubes slightly greater, on stripped than intact leaves, a very similar proportion of germlings formed apparently normal appressoria in both cases. This was true for f.sp. avenae on first- and fifth-formed leaves of susceptible and adult plant resistant oats, and on barley and wheat first leaves, and for f.sp. hordei on first leaves of barley, oat and wheat. The appressoria formed on stripped leaves not only appeared normal, but also formed haustoria with at least the same frequency as on intact leaves; in several experiments, a higher proportion formed haustoria in stripped than intact leaves. Wax removal did not affect the adult plant resistance of oat cv. Maldwyn, which limits haustorium formation by appressoria, indicating that epicuticular wax was not involved in this resistance. It is concluded that the physical structure of epicuticular wax is not involved in the recognition processes leading to normal germling development.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1365-3059.1990.tb02513.x
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