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Digitale Medien

Dominant and recessive deafness caused by mutations of a novel gene, TMC1 , required for cochlear hair-cell function (2002)

Kurima, Kiyoto ; Peters, Linda M. ; Yang, Yandan ; [weitere]

[s.l.] : Nature Publishing Group

Nature genetics 30 (2002), S. 277-284

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ISSN: 1546-1718

Quelle: Nature Archives 1869 - 2009

Thema: Biologie , Medizin

Notizen: [Auszug] Positional cloning of hereditary deafness genes is a direct approach to identify molecules and mechanisms underlying auditory function. Here we report a locus for dominant deafness, DFNA36, which maps to human chromosome 9q13–21 in a region overlapping the DFNB7/B11 locus for recessive ...

Materialart: Digitale Medien

URL: http://dx.doi.org/10.1038/ng842

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2

Digitale Medien

Beethoven, a mouse model for dominant, progressive hearing loss DFNA36 (2002)

Vreugde, Sarah ; Erven, Alexandra ; Kros, Corné J. ; [weitere]

[s.l.] : Nature Publishing Group

Nature genetics 30 (2002), S. 257-258

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ISSN: 1546-1718

Quelle: Nature Archives 1869 - 2009

Thema: Biologie , Medizin

Notizen: [Auszug] Despite recent progress in identifying genes underlying deafness, there are still relatively few mouse models of specific forms of human deafness. Here we describe the phenotype of the Beethoven (Bth) mouse mutant and a missense mutation in Tmc1 (transmembrane cochlear-expressed gene 1). ...

Materialart: Digitale Medien

URL: http://dx.doi.org/10.1038/ng848

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3

Digitale Medien

Advantage of rare HLA supertype in HIV disease progression (2003)

Trachtenberg, Elizabeth ; Korber, Bette ; Sollars, Cristina ; [weitere]

[s.l.] : Nature Publishing Group

Nature medicine 9 (2003), S. 928-935

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ISSN: 1546-170X

Quelle: Nature Archives 1869 - 2009

Thema: Biologie , Medizin

Notizen: [Auszug] The highly polymorphic human leukocyte antigen (HLA) class I molecules help to determine the specificity and repertoire of the immune response. The great diversity of these antigen-binding molecules confers differential advantages in responding to pathogens, but presents a major obstacle to ...

Materialart: Digitale Medien

URL: http://dx.doi.org/10.1038/nm893

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4

Digitale Medien

Binding of α-foetoprotein to murine T cells (1975)

DATTWYLER, RAYMOND J. ; MURGITA, ROBERT A. ; TOMASI, THOMAS B.

[s.l.] : Nature Publishing Group

Nature 256 (1975), S. 656-657

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ISSN: 1476-4687

Quelle: Nature Archives 1869 - 2009

Thema: Biologie , Chemie und Pharmazie , Medizin , Allgemeine Naturwissenschaft , Physik

Notizen: [Auszug] To define the cell type(s) affected by AFP we studied the binding of AFP to the surface of various cells involved in the immune reaction using direct immunofluorescence on preparations of thymus derived lymphochtes (T cells), bone marrow derived lymphocytes (B cells) and macrophages. Mouse ...

Materialart: Digitale Medien

URL: http://dx.doi.org/10.1038/256656a0

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5

Digitale Medien

Ageing The old worm turns more slowly (2002)

Kirkwood, Thomas B. L. ; Finch, Caleb E.

[s.l.] : Nature Publishing Group

Nature 419 (2002), S. 794-795

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ISSN: 1476-4687

Quelle: Nature Archives 1869 - 2009

Thema: Biologie , Chemie und Pharmazie , Medizin , Allgemeine Naturwissenschaft , Physik

Notizen: [Auszug] When the nematode worm Caenorhabditis elegans was first considered as a model for the study of ageing some 20 years ago, few foresaw how valuable it would prove to be. The past decade, in particular, has seen an explosion of work on the genetics of lifespan in this species. Building on pioneering ...

Materialart: Digitale Medien

URL: http://dx.doi.org/10.1038/419794a

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6

Digitale Medien

What's in a name? (1990)

MCALPINE, PHYLLIS J. ; SHOWS, THOMAS B.

[s.l.] : Nature Publishing Group

Nature 346 (1990), S. 616-616

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ISSN: 1476-4687

Quelle: Nature Archives 1869 - 2009

Thema: Biologie , Chemie und Pharmazie , Medizin , Allgemeine Naturwissenschaft , Physik

Notizen: [Auszug] SIR-Cedergren et al. in their Scientific Correspondence recently documented1 discrepancies in terminology for apparently homologous genes in different species of bacteria. This is a general problem applicable to comparisons of genes among all species, as in most instances genes have been conserved ...

Materialart: Digitale Medien

URL: http://dx.doi.org/10.1038/346616a0

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7

Digitale Medien

Tales of old (1991)

Kirkwood, Thomas B. L.

[s.l.] : Nature Publishing Group

Nature 352 (1991), S. 767-768

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ISSN: 1476-4687

Quelle: Nature Archives 1869 - 2009

Thema: Biologie , Chemie und Pharmazie , Medizin , Allgemeine Naturwissenschaft , Physik

Notizen: [Auszug] ONE of Aristotle's many claims to fame is as the great grandaddy of geronto-logical science. "It is not clear whether in animals or plants universally it is a single or diverse cause that makes some to be long-lived, others short-lived." Thus mused Aristotle some 23 centuries ago in his De ...

Materialart: Digitale Medien

URL: http://dx.doi.org/10.1038/352767b0

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8

Digitale Medien

Geometric phase shifts in chemical oscillators (1991)

Kagan, Michael L. ; Kepler, Thomas B. ; Epstein, Irving R.

[s.l.] : Nature Publishing Group

Nature 349 (1991), S. 506-508

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ISSN: 1476-4687

Quelle: Nature Archives 1869 - 2009

Thema: Biologie , Chemie und Pharmazie , Medizin , Allgemeine Naturwissenschaft , Physik

Notizen: [Auszug] A phase shift analogous to Berry's phase—the Hannay angle5—exists for classical mechanical hamiltonian (that is, conservative) systems, and the semi-classical connection between the two has been developed by Berry6. Examples of geometric phase shifts have been identified in quantum ...

Materialart: Digitale Medien

URL: http://dx.doi.org/10.1038/349506a0

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9

Digitale Medien

How to make a metalloprotein (2001)

Bartnikas, Thomas B. ; Gitlin, Jonathan D.

[s.l.] : Nature Publishing Group

Nature structural biology 8 (2001), S. 733-734

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ISSN: 1072-8368

Quelle: Nature Archives 1869 - 2009

Thema: Biologie , Medizin

Notizen: [Auszug] In the more than half century since the great Danish biochemist Kaj Linderstrøm-Lang first enunciated the concept of the structural hierarchy of proteins, the complex processes of protein folding and assembly have captured the imagination and focus of investigators from many diverse fields. ...

Materialart: Digitale Medien

URL: http://dx.doi.org/10.1038/nsb0901-733

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