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  • Springer  (129)
  • Nature Publishing Group  (8)
  • Geological Society of America (GSA)
  • Seismological Society of America
  • Seismological Society of America (SSA)
  • 2000-2004  (39)
  • 1995-1999  (91)
  • 1965-1969  (13)
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  • 1
    Electronic Resource
    Electronic Resource
    Effects of ammonium ions on the depolarization-induced and direct activation of the contractile apparatus in mechanically skinned fast-twitch skeletal muscle fibres of the rat (1996)
    Springer
    Journal of muscle research and cell motility 17 (1996), S. 611-616 
    Details
    ISSN: 1573-2657
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary Mechanically skinned fibre preparations from the extensor digitorum longus muscle of the rat were used to test whether a rise in myoplasmic [NH4 +] in the range 2–10 mm interferes with the mechanism of excitation-contraction coupling in fast-twitch mammalian muscle. Under our conditions (pH 7.10, Mg2+ 1 mm, temperature 23° C), [NH4 +] up to 10 mm had little effect on the Ca+-activated force and on the peak of the t-system depolarization-induced force response. However, the duration of the depolarization-induced force response was decreased significantly at [NH4 +] ≥2 mm. From these data we conclude that the intracellular accumulation of NH4 + is not likely to play a major role in fatigue. Nevertheless, the build up of NH4 + during fatigue, may have a significant inhibitory effect on the force output by decreasing the duration of the t-system depolarization-induced activation of the contractile apparatus.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00154055
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  • 2
    Electronic Resource
    Electronic Resource
    Microfluorometric analyses of glycogen in freshly dissected, single skeletal muscle fibres of the cane toad using a mechanically skinned fibre preparation (1998)
    Springer
    Journal of muscle research and cell motility 19 (1998), S. 631-638 
    Details
    ISSN: 1573-2657
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Abstract The main objective of this study was to analyse glycogen in single muscle fibres, using a recently developed microfluorometric method which detects subpicomol amounts of NADPH, glucose and glycogen (as glucosyl units) (detection limit 0.16–0.17pmol in a 25nl sample) without fluorochrome amplification. The fibres were freshly dissected from the twitch region of the iliofibularis muscle of the cane toad (Bufo marinus), and were mechanically skinned under paraffin oil to gain access to the intracellular compartments. The results show that: (1) glycogen concentrations in toad skeletal muscle fibres range between 25.8 and 369mmol glucosyl units/litre fibre volume; (2) there is a large variation in glycogen content between individual fibres from the iliofibularis muscle of one animal; (3) there are seasonal differences in the glycogen content of toad single muscle fibres; (4) the total amount of glycogen in single muscle fibres of the toad does not decrease significantly when storing the tissue, under paraffin oil, at 20–25°C for up to 6h or at 4°C for up to 24h; and (5) 15–26% of fibre glycogen can be washed in an aqueous solution at pH 5–7, within 5min, while 74–85% of fibre glycogen remains associated with the washed skinned fibre, even after 40min exposure of the skinned fibre preparation to the aqueous environment. The retention of most glycogen in the fibre preparation after mechanical removal of the plasma membrane and extensive washing indicates that in toad skeletal muscle fibres the largest proportion of glycogen is tightly bound to intracellular structures. The results also show that the skinned muscle fibre preparation is well suited for microfluorometric glycogen determination, since low molecular weight non-glycogen contributors to the fluorescence signal can be removed from the myoplasmic space prior to the glycogen hydrolysis step.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1023/A:1005377030193
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  • 3
    Electronic Resource
    Electronic Resource
    Observations on Chromocentres in Cultured Mouse Cells (1969)
    [s.l.] : Nature Publishing Group
    Nature 222 (1969), S. 1250-1253 
    Details
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] Counting and sizing of the chromocentres in mouse fibroblast-like cells is feasible. It has shown that, in spite of the great variations of chromocentres in a population of such cells, there are certain ...
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1038/2221250a0
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  • 4
    Electronic Resource
    Electronic Resource
    Ability of Counterflow Systems to Concentrate (1965)
    [s.l.] : Nature Publishing Group
    Nature 206 (1965), S. 1215-1219 
    Details
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] IN two recent papers1,2 Dr. G. G. Pinter and Dr. J. L. Shohet have discussed a model of the renal medulla. The central feature of this model is that even though the counter current multiplier action of Henle's loop is restricted to the thick segment of the ascending limb, that is to the outer zone ...
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1038/2061215a0
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  • 5
    Electronic Resource
    Electronic Resource
    Potassium Molybdenum Oxide ‘Bronzes’ (1965)
    [s.l.] : Nature Publishing Group
    Nature 206 (1965), S. 924-925 
    Details
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] The structures of these two phases, the erystallographie constants of which are given in Table 1, have now been determined and refined by three-dimensional Fourier and least-squares techniques by us. Both are layer structures containing sheets of irregular molybdenum-oxygen octa-hedra. The sheets, ...
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1038/206924b0
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  • 6
    Electronic Resource
    Electronic Resource
    Potentiation by an Antagonist (1969)
    [s.l.] : Nature Publishing Group
    Nature 222 (1969), S. 790-791 
    Details
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] Fig. 1. In each graph the ordinate ybdyb is the ratio of receptors occupied by agonist in the presence of both rapidly and slowly dissociating antagonists to those occupied by the agonist in the presence of only the slow antagonist. X, Y and Z represent the proportion of receptors occupied (in the ...
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1038/222790a0
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  • 7
    Electronic Resource
    Electronic Resource
    Fossil Burrows on the Coast of Kenya (1965)
    [s.l.] : Nature Publishing Group
    Nature 207 (1965), S. 850-851 
    Details
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] The rock containing the burrows resembles the coquinas described by Thompson1. It is cream-coloured granular limestone which in thin section is seen to consist of fragments of shell, with some foraminifera and a few quartz grains, cemented together by calcite. In outcrop the bedding is picked out ...
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1038/207850a0
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  • 8
    Electronic Resource
    Electronic Resource
    Vitamin addition: an option for sustainable activated sludge process effluent quality (2000)
    Springer
    Journal of industrial microbiology and biotechnology 24 (2000), S. 267-274 
    Details
    ISSN: 1476-5535
    Keywords: Keywords: vitamins; activated sludge; industrial wastewater; porous pots; Amtox™
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: The process performance and metabolic rates of samples of activated sludge dosed with vitamin supplements have been compared. After initial screening, four vitamins and two metals as single supplements and in pairs, were dosed continuously into the mixed liquor of an activated sludge simulation. Toxicity, oxygen demand removal, respiration rates and suspended solids were measured to monitor the effect on process efficiency. It was confirmed experimentally that an industrial wastewater stream did not contain a sufficient supply of micronutrients for efficient biological treatment. This was concluded from the observation that control sludge batches (receiving no supplements) averaged chemical oxygen demand removal efficiency of 58%. Dosing micronutrients into the mixed liquor produced removal efficiencies of up to 69%. Some of the supplements increased the respiration rate of the sludge while some decreased it, indicating a range of stimulatory and inhibitory effects. Complex interactions between micronutrients that were dosed simultaneously were evident. Several positive effects led to the conclusion that micronutrients have the potential to optimise process performance of activated sludge plants treating industrial wastewater. The addition of phosphorus/niacin and molybdenum/lactoflavin removed wastewater components that were toxic to nitrifiers as indicated through toxicity testing, thus protecting downstream nitrification/denitrification treatment processes. Journal of Industrial Microbiology & Biotechnology (2000) 24, 267–274.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1038/sj.jim.2900817
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  • 9
    Electronic Resource
    Electronic Resource
    Aminolaevulinic Acid-induced Photodynamic Therapy in the Treatment of Dysplastic Barrett's Oesophagus and Adenocarcinoma (1999)
    Springer
    Lasers in medical science 14 (1999), S. 278-285 
    Details
    ISSN: 1435-604X
    Keywords: Keywords: Adenocarcinoma; Aminolaevulinic acid; Barrett's oesophagus; Dysplasia; Photodynamic therapy
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine , Physics , Technology
    Notes: Abstract . Photodynamic therapy (PDT) may have a role in the prevention of oesophageal cancer. Ten patients with Barrett's oesophagus, three with low-grade dysplasia (LGD), four with high-grade dysplasia (HGD), one with carcinoma in situ and two with invasive carcinoma, were treated with PDT. All received 30 mg/kg aminolaevulinic acid (ALA) followed 4 h later by laser endoscopy. Half were treated with red light (630 nm; 100 mW/cm2 for 1000 s) and half with green light (514 nm; 100 mW/cm2 for 500 s). Columnar epithelial regression was seen in all patients with dysplasia (mean area decrease 44%; range 10–100%), with apparent elimination of dysplasia in all cases. In patients with in situ or invasive carcinoma, no response was seen. ALA-induced PDT, using either red or green light, produces effective ablation of dysplastic Barrett's oesophagus, hence may have a role in the prevention of oesophageal carcinoma, but has little effect on in situ or invasive adenocarcinoma.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s101030050095
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  • 10
    Electronic Resource
    Electronic Resource
    Mycorrhizae from Denali National Park and Preserve, Alaska (1995)
    Springer
    Mycorrhiza 6 (1995), S. 21-29 
    Details
    ISSN: 1432-1890
    Keywords: Key words Mycorrhizae ; Arctic-alpine ; Dark septate fungi
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Abstract  Roots of 40 taxa of higher plants (Pteridophyta, Spermatophyta) from two alpine study sites in Denali National Park and Preserve in central Alaska were examined for their mycorrhizal colonization. We observed ectomycorrhizae on six species: Betula nana, Salix reticulata, Salix polaris, Salix arctica, Polygonum viviparum, and Dryas octopetala. Seven taxa, Cassiope tetragona, Empetrum nigrum, Ledum palustre subsp. decumbens, Ledum palustre subsp. groenlandicum, Loiseleuria procumbens, Vaccinium uliginosum and Vaccinium vitis–idaea (all Ericales), had ericoid mycorrhizae. One species, Arctostaphylos alpina, formed a typical arbutoid mycorrhiza. Two species (Sibbaldia procumbens and Aconitum delphinifolium) showed well-developed VA mycorrhizae, whereas three species of plants (Lycopodium clavatum, Silene acaulis and Oxytropis scammaniana) had vesicles, but no arbuscules. The roots of 11 other plants (Lycopodium clavatum, Lycopodium selago, Silene acaulis, Gentiana algida, Lupinus arcticus, Oxytropis scammaniana, Pedicularis langsdorffii, Pedicularis capitata, Pedicularis verticillata, Artemisia sp. and Carex bigelowii) had a variety of intracellular colonizations which are referred to as dark septate fungi. No mycorrhizae were found on 12 other plants: Equisetum arvense, Equisetum variegatum, Lycopodium alpinum, Polygonum bistorta, Saxifraga hieracifolia, Saxifraga hirculus, Astragalus alpinus, Pedicularis kanei, Petasites frigidus, Carex podocarpa, Carex microchaeta and Poa arctica. A possible ecological role of dark septate fungi is discussed.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s005720050101
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