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  • 2000-2004  (54)
  • 1995-1999  (47)
  • 1975-1979  (72)
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  • 1
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    A receptor in pituitary and hypothalamus that functions in growth hormone release (1996)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1996-08-16
    Description: Small synthetic molecules termed growth hormone secretagogues (GHSs) act on the pituitary gland and the hypothalamus to stimulate and amplify pulsatile growth hormone (GH) release. A heterotrimeric GTP-binding protein (G protein)-coupled receptor (GPC-R) of the pituitary and arcuate ventro-medial and infundibular hypothalamus of swine and humans was cloned and was shown to be the target of the GHSs. On the basis of its pharmacological and molecular characterization, this GPC-R defines a neuroendocrine pathway for the control of pulsatile GH release and supports the notion that the GHSs mimic an undiscovered hormone.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Howard, A D -- Feighner, S D -- Cully, D F -- Arena, J P -- Liberator, P A -- Rosenblum, C I -- Hamelin, M -- Hreniuk, D L -- Palyha, O C -- Anderson, J -- Paress, P S -- Diaz, C -- Chou, M -- Liu, K K -- McKee, K K -- Pong, S S -- Chaung, L Y -- Elbrecht, A -- Dashkevicz, M -- Heavens, R -- Rigby, M -- Sirinathsinghji, D J -- Dean, D C -- Melillo, D G -- Patchett, A A -- Nargund, R -- Griffin, P R -- DeMartino, J A -- Gupta, S K -- Schaeffer, J M -- Smith, R G -- Van der Ploeg, L H -- New York, N.Y. -- Science. 1996 Aug 16;273(5277):974-7.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Merck Research Laboratories, Rahway, NJ 07065, USA.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/8688086" target="_blank"〉PubMed〈/a〉
    Keywords: Amino Acid Sequence ; Animals ; Base Sequence ; Cell Line ; Codon ; DNA, Complementary/genetics ; GTP-Binding Proteins/metabolism ; Growth Hormone/*secretion ; Hormones/*metabolism ; Humans ; Hypothalamus, Middle/chemistry ; Indoles/*metabolism/pharmacology ; Macaca mulatta ; Molecular Sequence Data ; Oligopeptides/*metabolism ; Pituitary Gland/chemistry ; RNA, Complementary/genetics ; Rats ; Receptors, Cell Surface/analysis/chemistry/genetics/*metabolism ; *Receptors, G-Protein-Coupled ; Receptors, Ghrelin ; Spiro Compounds/*metabolism/pharmacology ; Swine
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
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    PAPER CURRENT
  • 2
    Electronic Resource
    Electronic Resource
    REPLY TO COMMENTS ON “HIDDEN LAYER PROBLEM IN SEISMIC REFRACTION WORK’ BY SCHMÖLLER (1978)
    Oxford, UK : Blackwell Publishing Ltd
    Geophysical prospecting 26 (1978), S. 0 
    Details
    ISSN: 1365-2478
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Geosciences , Physics
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1365-2478.1978.tb01623.x
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  • 3
    Electronic Resource
    Electronic Resource
    HIDDEN LAYER PROBLEM IN SEISMIC REFRACTION WORK (1975)
    Oxford, UK : Blackwell Publishing Ltd
    Geophysical prospecting 23 (1975), S. 0 
    Details
    ISSN: 1365-2478
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Geosciences , Physics
    Notes: The hidden layer problem in seismic refraction work has been studied for three velocity configurations – the intermediate layer having (a) lower, (b) intermediate and (c) higher velocity than the underlying and overlying beds. It has been shown that conventional methods fail to locate the presence of the intermediate layer for the cases (a) and (c) and lead to errors in calculating the depth to the bedrock. For the case (b), it is possible to interpret the first arrival travel time analytically as an alternative to Green's graphical approach. It has been suggested that the hidden layer may be detected in all the three cases if converted S waves are also recorded in the seismogram.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1365-2478.1975.tb01550.x
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  • 4
    Electronic Resource
    Electronic Resource
    REFLECTIONS AND REFRACTIONS FROM CURVED INTERFACES: MODEL STUDY (1978)
    Oxford, UK : Blackwell Publishing Ltd
    Geophysical prospecting 26 (1978), S. 0 
    Details
    ISSN: 1365-2478
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Geosciences , Physics
    Notes: Reflections and refractions from curved interfaces were studied on two dimensional scale models. Time of arrival, amplitude and character of reflected, converted, and refracted waves were mainly used for this study. Some reflected refractions, refracted reflections and diffractions were also considered. It was possible to separate PS and SP waves and to study their amplitude and character separately. From the amplitude study of refracted arrivals it was concluded that the refracted ray path penetrates into the high velocity layer rather than propagating along the interface. Although most of the results are interesting from the theoretical point of view, a few applications to exploration problems are suggested.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1365-2478.1978.tb01578.x
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  • 5
    Electronic Resource
    Electronic Resource
    Immobilization of cadmium and zinc in soil by Al-montmorillonite and gravel sludge (1998)
    Oxford, UK : Blackwell Science Ltd
    European journal of soil science 49 (1998), S. 0 
    Details
    ISSN: 1365-2389
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Geosciences , Agriculture, Forestry, Horticulture, Fishery, Domestic Science, Nutrition
    Notes: We investigated the potential of montmorillonite, Al-montmorillonite and gravel sludge to immobilize polluting heavy metals in agricultural soil. Batch experiments showed that both Al-montmorillonite and montmorillonite immobilized zinc and cadmium. Zinc was bound specifically on Al-montmorillonite and became increasingly incorporated into the interlayer hydroxy-Al polymer, whereas there was no specific sorption on montmorillonite. Cadmium was bound on montmorillonite and Al-montmorillonite unspecifically by cation exchange, but there was no incorporation into the lattice.In pot experiments montmorillonite, Al-montmorillonite, or gravel sludge were added to a soil contaminated with zinc and cadmium. Increasing doses of these agents decreased the concentrations of NaNO3-extractable zinc and cadmium. Aluminium-montmorillonite and gravel sludge were more efficient than montmorillonite in immobilizing both zinc and cadmium. Remobilization tests at pH between 4 and 5.5 showed that cadmium and zinc desorbed more easily from montmorillonite than from Al-montmorillonite. Gravel sludge application increased the buffer capacity of the contaminated soil substantially. The binding agents decreased zinc concentrations in red clover (Trifolium pratense), and gravel sludge also reduced the cadmium concentrations.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1046/j.1365-2389.1998.00140.x
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  • 6
    Electronic Resource
    Electronic Resource
    An instrument for automatic measurements of critical current of superconductors in pulse mode (1999)
    [S.l.] : American Institute of Physics (AIP)
    Review of Scientific Instruments 70 (1999), S. 1486-1493 
    Details
    ISSN: 1089-7623
    Source: AIP Digital Archive
    Topics: Physics , Electrical Engineering, Measurement and Control Technology
    Notes: An instrument has been developed for direct measurement of critical current and plotting of current–voltage (I–V) characteristics of superconductors in pulse mode. For these measurements, current pulses of increasing height are applied to sample and the voltage developed across the sample is monitored using a low noise voltage measuring circuit. Different sources of error responsible for limiting accuracy of pulse measurements techniques are discussed. A compensation network has been developed to reduce inductively induced voltages generated during pulse measurements, to negligible values. The instrument enables automatic critical current measurement with 1–10 μV/cm criteria in pulse mode without a computer and has voltage sensitivity of 10 nV. Critical current as a function of temperature/magnetic field and I–V characteristics of Bi-2212 single crystal and Y-123 thin films have been plotted using the circuit and the results have been compared with those obtained using direct current measurements. © 1999 American Institute of Physics.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1063/1.1149611
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  • 7
    Electronic Resource
    Electronic Resource
    Hydroboration. XXXIX. 1,3,2-Benzodioxaborole (catecholborane) as a new hydroboration reagent for alkenes and alkynes. General synthesis of alkane- and alkeneboronic acids and esters via hydroboration. Directive effects in the hydroboration of alkenes and alkynes with catecholborane (1975)
    s.l. : American Chemical Society
    Journal of the American Chemical Society 97 (1975), S. 5249-5255 
    Details
    ISSN: 1520-5126
    Source: ACS Legacy Archives
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1021/ja00851a038
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  • 8
    Electronic Resource
    Electronic Resource
    Modification of the Mojonnier fat-testing method for soy-protein-lipid concentrate (1978)
    s.l. : American Chemical Society
    Journal of agricultural and food chemistry 26 (1978), S. 977-978 
    Details
    ISSN: 1520-5118
    Source: ACS Legacy Archives
    Topics: Agriculture, Forestry, Horticulture, Fishery, Domestic Science, Nutrition , Process Engineering, Biotechnology, Nutrition Technology
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1021/jf60218a025
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  • 9
    Electronic Resource
    Electronic Resource
    DECISION RULES IN PRODUCTION PLANNING UNDER CHANGE-CONSTRAINED SALES* (1977)
    Oxford, UK : Blackwell Publishing Ltd
    Decision sciences 8 (1977), S. 0 
    Details
    ISSN: 1540-5915
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Economics
    Notes: Alternative decision rules for aggregate production scheduling are specified here under chance-constrained sales and compared with the HMMS model. These rules are evaluated for their performance on the basis of simulated data on sales and it is found that the linear decision rules of the HMMS model can be considerably improved.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1540-5915.1977.tb01099.x
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  • 10
    Electronic Resource
    Electronic Resource
    SCAR marker tagged to the alien leaf rust resistance gene Lr19 uniquely marking the Agropyron elongatum-derived gene Lr24 in wheat: a revision (2004)
    Oxford, UK : Blackwell Publishing Ltd
    Plant breeding 123 (2004), S. 0 
    Details
    ISSN: 1439-0523
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Agriculture, Forestry, Horticulture, Fishery, Domestic Science, Nutrition
    Notes: A sequence characterized amplified region (SCAR) marker tagged to an Agropyron elongatum-derived leaf rust resistance (Lr) gene Lr19 was validated on 18 known alien Lr gener in near-isogenic lines (NILs) in the variety ‘Thatcher’, along with three wheat cultivers carrying Lr24 and two carrying Lr19. The marker was expressed only in the Lr24 lines confirming that the marker tagged the geneLr24. The monomorphic expression of the SCAR marker in 10NIL pairs for Lr19 and Lr24 revealed that each NIL pair possessed the same gene, Lr24. The donor parents used in the NIL pairs for Lr19 (‘Sunstar*6/C80-1′) and Lr24 (‘TR380-14*7/3Ag#14′) amplified the same fragment. Nonsegregation for leaf rust in the F2 population of the cross between the above donor parents confirmed the presence of the same gene in the two parents. Apparently, a genuine parent stock of ‘Sunstar*6/C80-1’ was not involved in the development of the NIL pairs for Lr19 due to an improper maintence bredding protocol either at source or destination which went undetected in the absence of signs of virulence for either gene in the region.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1439-0523.2004.00971.x
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