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  • 1
    Electronic Resource
    Electronic Resource
    The EU ‘partnership principle’: still a sustainable governance device across multiple administrative arenas? (2002)
    Oxford, UK and Boston, USA : Blackwell Publishers Ltd
    Public administration 80 (2002), S. 0 
    Details
    ISSN: 1467-9299
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Political Science , Economics
    Notes: This article analyses the ‘partnership principle’– which is of particular importance for multilevel governance interpretations of European integration – as it evolved in EU regional policy–making. After sketching in the crucial analytical lines of the current debate on ‘partnership’ on the example of the implementation of the EU structural policy in Germany, I examine how it functions. A closer look at two important sub–fields of ‘partnership’–‘societal participation’ and ‘policy evaluation’– reveals that theoretical expectations regarding its transforming potential, in terms of pitting supranational and subnational actors against central state authority and thereby circumventing the latter, have not materialized. On the contrary, recently rising resentment and out–and–out conflict between the European Commission and regional authorities so far point to theoretically unexpected limitations of ‘partnership’, calling into question whether it is an appropriate and sustainable inter–administrative co–ordination device – at least when viewed from the perspective of the EU multilevel governance thesis. In the light of the reported insights into the practice of ‘partnership’, this ‘new mode of EU governance’ thus needs to be reassessed.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/1467-9299.00328
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  • 2
    Electronic Resource
    Electronic Resource
    Identification of tissue transglutaminase as the autoantigen of celiac disease (1997)
    [s.l.] : Nature Publishing Group
    Nature medicine 3 (1997), S. 797-801 
    Details
    ISSN: 1546-170X
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Medicine
    Notes: [Auszug] Celiac disease is characterized by small intestinal damage with loss of absorptive villi and hyperplasia of the crypts, typically leading to malabsorption1. In addition to nutrient deficiencies, prolonged celiac disease is associated with an increased risk for malignancy, especially intestinal ...
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1038/nm0797-797
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  • 3
    Electronic Resource
    Electronic Resource
    Configuration Maintenance for Distributed Applications Management (2000)
    Springer
    Journal of network and systems management 8 (2000), S. 219-244 
    Details
    ISSN: 1573-7705
    Keywords: Distributed application management ; configuration management ; management services
    Source: Springer Online Journal Archives 1860-2000
    Topics: Computer Science
    Notes: Abstract The MANDAS project has defined a layered architecture for the management of distributed applications. In this paper we examine a vertical slice of this architecture, namely the management applications and services related to configuration management. We introduce an information model which captures the configuration information for distributed applications and discuss a repository service based on the model. We define a set of services and management applications to support maintenance of configuration information, and describe how the different types of configuration information are collected. Finally, we present two management applications that use configuration information.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1023/A:1009499124873
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  • 4
    Electronic Resource
    Electronic Resource
    Fault Management in Distributed Systems: A Policy-Driven Approach (2000)
    Springer
    Journal of network and systems management 8 (2000), S. 499-525 
    Details
    ISSN: 1573-7705
    Keywords: Distributed systems ; policy-driven management ; DCE ; distributed applications management
    Source: Springer Online Journal Archives 1860-2000
    Topics: Computer Science
    Notes: Abstract Managing the availability and performance of a distributed system involves monitoring the behavior of the system, identifying system problems, and correcting those problems. Each of these tasks requires some expertise, such as an understanding of the mechanics of the underlying system components. As the size and complexity of these systems increases, and the number of distributed applications executing on these systems increases, managing the availability and performance of distributed systems becomes more difficult. Little research has focused on embedding systems management expertise into a management application for a distributed system. In this paper we describe a rule-based management application for a commercially available distributed computing environment that is capable of monitoring the distributed system, detecting system service-related performance and availability problems, and generating corrective actions to correct the problems.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1023/A:1026482400326
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  • 5
    Electronic Resource
    Electronic Resource
    Advances in systems and application management: Managing large distributed computing environments (1996)
    Springer
    Journal of network and systems management 4 (1996), S. 477-480 
    Details
    ISSN: 1573-7705
    Source: Springer Online Journal Archives 1860-2000
    Topics: Computer Science
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02283165
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  • 6
    Electronic Resource
    Electronic Resource
    Biotransformation of halophenols by a thermophilic Bacillus sp. (1996)
    Springer
    Biodegradation 7 (1996), S. 455-461 
    Details
    ISSN: 1572-9729
    Keywords: Bacillus ; chlorophenols ; degradation ; thermophilic
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Energy, Environment Protection, Nuclear Power Engineering , Agriculture, Forestry, Horticulture, Fishery, Domestic Science, Nutrition
    Notes: Abstract The thermophilic Bacillus sp. A2 transformed various halophenols. 2-Chlorophenol, 2-bromophenol, 3-bromophenol and 2-fluorophenol were transformed under resting cell conditions at 60°C to 3-chlorocatechol, 3-bromocatechol, 4-bromocatechol and 3-fluorocatechol, respectively. The hydroxylation of 3-bromophenol occurred at the proximal and distal position relative to the halogen substituent. In complex medium this strain completely transformed 2-chlorophenol and 2-bromophenol at concentrations up to 1 mM. Concomitantly, an accumulation of oxygen-and temperature sensitive halocatechols was observed. 3-Chlorocatechol possesses a half-life of 11.5 h at 60°C and is therefore readily decomposed during incubation. The hydroxylating system was present in phenolgrown cells but not in glucose-grown cells. The hydroxylase activity could also be induced by 2-chlorophenol. The product, 3-chlorocatechol, is not a substrate for the catechol 2,3-dioxygenase.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00115292
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  • 7
    Electronic Resource
    Electronic Resource
    Methods of double-stranded RNA-mediated gene inactivation in Arabidopsis and their use to define an essential gene in methionine biosynthesis (2000)
    Springer
    Plant molecular biology 44 (2000), S. 759-775 
    Details
    ISSN: 1573-5028
    Keywords: Arabidopsis thaliana ; cystathionine β-lyase ; double-stranded RNA ; gene silencing ; methionine biosynthesis ; RNA interference
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Abstract Controlled down-regulation of endogenous plant gene expression is a useful tool, but antisense and sense silencing lack predictability. Recent studies show that expression of both antisense and sense RNA together is an effective means of inactivating reporter and viral genes in plants. We created transgenic plants expressing antisense and sense RNA together in a single `double-stranded RNA' (dsRNA) transcript. This approach shows great promise as a highly effective means for reducing gene function. With this approach, we demonstrated that the Arabidopsis cystathionine β-lyase gene, which encodes a methionine biosynthetic enzyme, is essential for viability. Inactivation of this gene was rescued by the addition of methionine to the growth medium. Compared to antisense and sense constructs, the dsRNA construct showed a much more consistent and complete suppression of gene activity. Additionally, expression of a transcript with a spacer sequence containing an unrelated gene between antisense and sense luciferase gene fragments led to stronger inactivation of a second luciferase transgene than did constructs with a minimal spacing between sense and antisense fragments. However, the gene in the spacer region was neither functionally expressed nor functional in silencing a second, unlinked homologous transgene.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1023/A:1026584607941
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  • 8
    Electronic Resource
    Electronic Resource
    Korrespondenz (1997)
    Weinheim : Wiley-Blackwell
    Chemie in unserer Zeit 31 (1997), S. 47-48 
    Details
    ISSN: 0009-2851
    Keywords: Chemistry ; Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/ciuz.19970310113
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  • 9
    Electronic Resource
    Electronic Resource
    Synthesis of 2,3,6,8-Tetrahydroxybenzofuro[3,2-b][1]benzopyrylium Chloride (Riccionidin A) (1998)
    New York, NY : Wiley-Blackwell
    Journal für Praktische Chemie/Chemiker-Zeitung 340 (1998), S. 271-273 
    Details
    ISSN: 0941-1216
    Keywords: Chemistry ; Organic Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Notes: The liverwort pigment riccionidin A (1) was synthesized in a single preparative step from simple starting materials by a double condensation reaction.
    Additional Material: 3 Tab.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/prac.19983400312
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  • 10
    Electronic Resource
    Electronic Resource
    Modification of isotactic poly(propylene) by oxygen and helium plasma with reference to thermo-oxidative stability (1996)
    Weinheim : Wiley-Blackwell
    Macromolecular Chemistry and Physics 197 (1996), S. 61-82 
    Details
    ISSN: 1022-1352
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology , Physics
    Notes: The modification of isotactic poly(propylene) (PP) foils by reactive (O2) and inert (He) gas plasma treatment was studied with relevance to surface structure and thermo-oxidative stability for different treatment times. The following effects were investigated: change of non-helical (atactic or amorphous) content in the surface region and formation of vinyl and vinylidene groups by frustrated multiple internal reflection Fourier transform infrared spectroscopy (FMIR-FTIR), formation of peroxyl redicals by electron spin resonance spectroscopy (ESR) and change of the invariant activation energy of degradation by thermogravimetric analysis (TGA). For the latter a new kinetic evaluation method was used based on a selection of multiple step model to determine the invariant Arrhenius constants, e.g., activation energy and preexponential factor, for the weight loss during thermoxidative degradation of untreated and, for the first time, of plasma-treated PP. Several thermogravimetric curves under different temperature scanning conditions have been evaluated with different solid state models as well as with a selection of different multiple step reaction pathways. With a limitation to total weight loss of 60% of the mass for an untreated PP and applying a most probable kinetic model consisting of one consecutive and one parallel reaction step, the activation energies were found to be 84.2 ± 1.0 and 73.2 ± 1.0 kJ/mol for the initial and the consecutive reaction and 137.8 ± 3.0 kJ/mol for the parallel reaction. The corresponding data of the plasma-treated samples are 80 ± 1.0 and 71.0 ± 1.0 kJ/mol for the initial and the consecutive reaction, while the activation energy for the parallel reaction remained almost unchanged. Unexpectedly, we found the He plasma treatment to decrease the activation energies of the first and consecutive reaction nonlinearly and within the first 600 s to a larger extent than O2 plasma treatment. Based on this kinetic model, a modified mechanism for the thermo-oxidative degradation of PP is proposed in terms of elementary degradation reactions and will be discussed with reference to literature data.
    Additional Material: 16 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/macp.1996.021970105
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