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  • Springer  (206)
  • International Union of Crystallography  (18)
  • Geological Society of America (GSA)
  • Periodicals Archive Online (PAO)
  • Seismological Society of America (SSA)
  • 2000-2004  (38)
  • 1995-1999  (94)
  • 1990-1994  (92)
  • 1950-1954  (8)
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  • 1
    Electronic Resource
    Electronic Resource
    Effects of ammonium ions on the depolarization-induced and direct activation of the contractile apparatus in mechanically skinned fast-twitch skeletal muscle fibres of the rat (1996)
    Springer
    Journal of muscle research and cell motility 17 (1996), S. 611-616 
    Details
    ISSN: 1573-2657
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary Mechanically skinned fibre preparations from the extensor digitorum longus muscle of the rat were used to test whether a rise in myoplasmic [NH4 +] in the range 2–10 mm interferes with the mechanism of excitation-contraction coupling in fast-twitch mammalian muscle. Under our conditions (pH 7.10, Mg2+ 1 mm, temperature 23° C), [NH4 +] up to 10 mm had little effect on the Ca+-activated force and on the peak of the t-system depolarization-induced force response. However, the duration of the depolarization-induced force response was decreased significantly at [NH4 +] ≥2 mm. From these data we conclude that the intracellular accumulation of NH4 + is not likely to play a major role in fatigue. Nevertheless, the build up of NH4 + during fatigue, may have a significant inhibitory effect on the force output by decreasing the duration of the t-system depolarization-induced activation of the contractile apparatus.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00154055
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  • 2
    Electronic Resource
    Electronic Resource
    Microfluorometric analyses of glycogen in freshly dissected, single skeletal muscle fibres of the cane toad using a mechanically skinned fibre preparation (1998)
    Springer
    Journal of muscle research and cell motility 19 (1998), S. 631-638 
    Details
    ISSN: 1573-2657
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Abstract The main objective of this study was to analyse glycogen in single muscle fibres, using a recently developed microfluorometric method which detects subpicomol amounts of NADPH, glucose and glycogen (as glucosyl units) (detection limit 0.16–0.17pmol in a 25nl sample) without fluorochrome amplification. The fibres were freshly dissected from the twitch region of the iliofibularis muscle of the cane toad (Bufo marinus), and were mechanically skinned under paraffin oil to gain access to the intracellular compartments. The results show that: (1) glycogen concentrations in toad skeletal muscle fibres range between 25.8 and 369mmol glucosyl units/litre fibre volume; (2) there is a large variation in glycogen content between individual fibres from the iliofibularis muscle of one animal; (3) there are seasonal differences in the glycogen content of toad single muscle fibres; (4) the total amount of glycogen in single muscle fibres of the toad does not decrease significantly when storing the tissue, under paraffin oil, at 20–25°C for up to 6h or at 4°C for up to 24h; and (5) 15–26% of fibre glycogen can be washed in an aqueous solution at pH 5–7, within 5min, while 74–85% of fibre glycogen remains associated with the washed skinned fibre, even after 40min exposure of the skinned fibre preparation to the aqueous environment. The retention of most glycogen in the fibre preparation after mechanical removal of the plasma membrane and extensive washing indicates that in toad skeletal muscle fibres the largest proportion of glycogen is tightly bound to intracellular structures. The results also show that the skinned muscle fibre preparation is well suited for microfluorometric glycogen determination, since low molecular weight non-glycogen contributors to the fluorescence signal can be removed from the myoplasmic space prior to the glycogen hydrolysis step.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1023/A:1005377030193
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  • 3
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    Decision Rules Used by Male and Female Business Students in Making Ethical Value Judgments: Another Look (1993)
    Dordrecht : Periodicals Archive Online (PAO)
    Journal of Business Ethics. 12:3 (1993:Mar.) 227 
    Details
    ISSN: 0167-4544
    Topics: Philosophy , Economics
    URL: http://gateway.proquest.com/openurl?url_ver=Z39.88-2004&res_dat=xri:pao:&rft_dat=xri:pao:article:m089-1993-012-03-000006
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  • 4
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    Ethical Congruency of Constiituent Groups (1995)
    Dordrecht : Periodicals Archive Online (PAO)
    Journal of Business Ethics. 14:2 (1995:Feb.) 145 
    Details
    ISSN: 0167-4544
    Topics: Philosophy , Economics
    URL: http://gateway.proquest.com/openurl?url_ver=Z39.88-2004&res_dat=xri:pao:&rft_dat=xri:pao:article:m089-1995-014-02-000006
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  • 5
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    "Cardiac Myocyte - Connective Tissue Interactions in Health and Disease", edited by T.F. Robinson and R.K.H. Kinne (Book Review) (1992)
    Baltimore : Periodicals Archive Online (PAO)
    Human Biology. 64:2 (1992:Apr.) 263 
    Details
    ISSN: 0018-7143
    Topics: Biology
    Notes: Book Reviews
    URL: http://gateway.proquest.com/openurl?url_ver=Z39.88-2004&res_dat=xri:pao:&rft_dat=xri:pao:article:5243-1992-064-02-000015
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  • 6
    Electronic Resource
    Electronic Resource
    Theory of the vacuum drying of frozen tissues (1953)
    Springer
    Bulletin of mathematical biology 15 (1953), S. 411-429 
    Details
    ISSN: 1522-9602
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Mathematics
    Notes: Abstract A general theory of the drying of frozen tissue is developed and applied to the measurement of the drying rate of frozen guinea pig liver. It is shown that for a given temperature of the subliming ice crystals the mininum drying time of a piece of guinea pig liver is greater than the minimum sublimation time of a piece of ice of the same size and shape by a factor of the order of one thousand. This fact has many implications in the design of freeze-dry apparatus which will be developed in a following paper.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02476434
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  • 7
    Electronic Resource
    Electronic Resource
    Externally driven countercurrent multiplication in a mathematical model of the urinary concentrating mechanism of the renal inner medulla (1994)
    Springer
    Bulletin of mathematical biology 56 (1994), S. 491-514 
    Details
    ISSN: 1522-9602
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Mathematics
    Notes: Abstract Substitution of measured permeabilities into mathematical models of the concentrating mechanism of the renal inner medulla yields less than the known urine osmolalities. To gain a better understanding of the mechanism we analyse a model in which a force of unspecified origin [expressed as fraction, ɛ, of entering descending thin limb (DTL) concentration] drives fluid from DTL to interstitial vascular space (CORE), thus concentrating the solution in DTL. When flow in the DTL reverses at the hairpin bend of the loop of Henle, the high solute permeability of ascending thin limb (ATL) permits solute to diffuse into the CORE thus permitting ɛ to be multiplied many-fold. Behavior of the model is described by two non-linear differential equations. In the limit for infinite salt permeability of ATL the two equations reduce to a single equation that is formally identical with that for the Hargitay and Kuhn multiplier, which assumes fluid transport directly from DTL to ATL (Z. Electrochem. Angew. Phys. Chem. 55, 539, 1951). Solutions of the equations describing the model with parameters taken from perfused thin limbs show that urine osmolalities of the order of 5000 mosm L−1 can be generated by forces of the order of 20 mosm L−1. It seems probable that mammals including desert rodents use some variant of this basic mechanism for inner medullary concentration.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02460468
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  • 8
    Electronic Resource
    Electronic Resource
    Vitamin addition: an option for sustainable activated sludge process effluent quality (2000)
    Springer
    Journal of industrial microbiology and biotechnology 24 (2000), S. 267-274 
    Details
    ISSN: 1476-5535
    Keywords: Keywords: vitamins; activated sludge; industrial wastewater; porous pots; Amtox™
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: The process performance and metabolic rates of samples of activated sludge dosed with vitamin supplements have been compared. After initial screening, four vitamins and two metals as single supplements and in pairs, were dosed continuously into the mixed liquor of an activated sludge simulation. Toxicity, oxygen demand removal, respiration rates and suspended solids were measured to monitor the effect on process efficiency. It was confirmed experimentally that an industrial wastewater stream did not contain a sufficient supply of micronutrients for efficient biological treatment. This was concluded from the observation that control sludge batches (receiving no supplements) averaged chemical oxygen demand removal efficiency of 58%. Dosing micronutrients into the mixed liquor produced removal efficiencies of up to 69%. Some of the supplements increased the respiration rate of the sludge while some decreased it, indicating a range of stimulatory and inhibitory effects. Complex interactions between micronutrients that were dosed simultaneously were evident. Several positive effects led to the conclusion that micronutrients have the potential to optimise process performance of activated sludge plants treating industrial wastewater. The addition of phosphorus/niacin and molybdenum/lactoflavin removed wastewater components that were toxic to nitrifiers as indicated through toxicity testing, thus protecting downstream nitrification/denitrification treatment processes. Journal of Industrial Microbiology & Biotechnology (2000) 24, 267–274.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1038/sj.jim.2900817
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  • 9
    Electronic Resource
    Electronic Resource
    Aminolaevulinic Acid-induced Photodynamic Therapy in the Treatment of Dysplastic Barrett's Oesophagus and Adenocarcinoma (1999)
    Springer
    Lasers in medical science 14 (1999), S. 278-285 
    Details
    ISSN: 1435-604X
    Keywords: Keywords: Adenocarcinoma; Aminolaevulinic acid; Barrett's oesophagus; Dysplasia; Photodynamic therapy
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine , Physics , Technology
    Notes: Abstract . Photodynamic therapy (PDT) may have a role in the prevention of oesophageal cancer. Ten patients with Barrett's oesophagus, three with low-grade dysplasia (LGD), four with high-grade dysplasia (HGD), one with carcinoma in situ and two with invasive carcinoma, were treated with PDT. All received 30 mg/kg aminolaevulinic acid (ALA) followed 4 h later by laser endoscopy. Half were treated with red light (630 nm; 100 mW/cm2 for 1000 s) and half with green light (514 nm; 100 mW/cm2 for 500 s). Columnar epithelial regression was seen in all patients with dysplasia (mean area decrease 44%; range 10–100%), with apparent elimination of dysplasia in all cases. In patients with in situ or invasive carcinoma, no response was seen. ALA-induced PDT, using either red or green light, produces effective ablation of dysplastic Barrett's oesophagus, hence may have a role in the prevention of oesophageal carcinoma, but has little effect on in situ or invasive adenocarcinoma.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s101030050095
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  • 10
    Electronic Resource
    Electronic Resource
    Spiral hexagonal circle packings in the plane (1994)
    Springer
    Geometriae dedicata 49 (1994), S. 39-70 
    Details
    ISSN: 1572-9168
    Source: Springer Online Journal Archives 1860-2000
    Topics: Mathematics
    Notes: Abstract We discuss an intriguing geometric algorithm which generates infinite spiral patterns of packed circles in the plane. Using Kleinian group and covering theory, we construct a complex parametrization of all such patterns and characterize those whose circles have mutually disjoint interiors. We prove that these ‘coherent’ spirals, along with the regular hexagonal packing, give all possible hexagonal circle packings in the plane. Several examples are illustrated.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01263534
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