ALBERT

All Library Books, journals and Electronic Records Telegrafenberg

feed icon rss

Your email was sent successfully. Check your inbox.

An error occurred while sending the email. Please try again.

Proceed reservation?

Export
  • 1
    Keywords: Electromagnetism ; Engineering ; Laser physics ; Remote sensing
    ISBN: 9781402065033
    Language: English
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
  • 2
    ISSN: 1365-2958
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Biology , Medicine
    Notes: The response regulator PprB and its cognate sensor PprA were recently reported as a two-component regulatory system that controls membrane permeability and antibiotic sensitivity of Pseudomonas aeruginosa. We found that a Tn5 insertion mutation in pprB caused a drastic reduction in virulence factor production and cell motility. A transcriptome analysis revealed that 175 genes were regulated by PprB. Among the 113 PprB-activated genes, 85.5% are known to be activated by N-3-oxo-dodecanoyl-homoserine lactone (OdDHL) and N-butanoyl-homoserine lactone (BHL). In particular, the expression of lasI, rhlI and rhlR, which encode key components of the las and rhl quorum-sensing (QS) systems, were significantly decreased in the pprB mutant. These data suggest that PprB might regulate QS signal production. Measurement of OdDHL and BHL in cultures of the mutant sustained this hypothesis. By using various OdDHL- or BHL-responsive QS reporter systems, including lasB–lacZ, lasI–lacZ and rsaL–lacZ, we found that the mutation in pprB resulted in a large decrease in the sensitivity of P. aeruginosa to exogenous OdDHL. However, there was no difference in sensitivity to BHL. Further analysis showed that the OdDHL influx was significantly reduced in the pprB mutant. We conclude that PprB is a novel QS modulator that positively regulates N-acylhomoserine lactone production probably by affecting the OdDHL signal influx and thereby influences global expression of the QS-dependent genes.
    Type of Medium: Electronic Resource
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
  • 3
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Science Ltd
    Molecular microbiology 58 (2005), S. 0 
    ISSN: 1365-2958
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Biology , Medicine
    Notes: Human pathogen Pseudomonas aeruginosa uses quorum-sensing (QS) signalling systems to synchronize the production of virulence factors. There are two interrelated QS systems, las and rhl, in P. aeruginosa. In addition to this complexity, a number of transcriptional regulators were shown to have complicated interplays with las and rhl central QS components. Here, we describe a novel virulence and QS modulator (VqsM) that positively regulates the QS systems in P. aeruginosa. Mutation in vqsM resulted in much reduced production of N-acylhomoserine lactones (AHLs) and extracellular enzymes. Sequence analysis revealed that vqsM encodes a transcriptional regulator with an AraC-type helix–turn–helix DNA binding domain at the C-terminal of the peptide. Global gene expression profile analysis showed at least a total of 302 genes to be influenced, directly or indirectly, by VqsM. Among the 203 VqsM-promoted genes, 52.2% were known to be QS upregulated. Several genes encoding the key regulators implicated in QS, such as rhlR, rsaL, vqsR, mvfR, pprB and rpoS, and two AHL synthesis genes, lasI and rhlI, were suppressed in the vqsM mutant. Similar to the ‘AHL-blind’ phenotype of vqsR and pprB mutants, vqsM mutant did not respond to external addition of N-3-oxo-dodecanoyl-homoserine lactone signals. Moreover, overexpression of vqsR in vqsM mutant more or less restored the production of both AHL and virulence factors. The results demonstrate that VqsM, largely through modulation of vqsR expression, plays a vital role in regulation of QS signalling in P. aeruginosa.
    Type of Medium: Electronic Resource
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
  • 4
    Electronic Resource
    Electronic Resource
    [s.l.] : Nature Publishing Group
    Nature 449 (2007), S. 595-598 
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] Crown-group crustaceans (Eucrustacea) are common in the fossil record of the past 500 million years back to the early Ordovician period, and very rare representatives are also known from the late Middle and Late Cambrian periods. Finds in Lower Cambrian rocks of the Phosphatocopina, ...
    Type of Medium: Electronic Resource
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
  • 5
    Electronic Resource
    Electronic Resource
    s.l. ; Stafa-Zurich, Switzerland
    Materials science forum Vol. 475-479 (Jan. 2005), p. 3787-3790 
    ISSN: 1662-9752
    Source: Scientific.Net: Materials Science & Technology / Trans Tech Publications Archiv 1984-2008
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Type of Medium: Electronic Resource
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
  • 6
    Electronic Resource
    Electronic Resource
    s.l. ; Stafa-Zurich, Switzerland
    Key engineering materials Vol. 368-372 (Feb. 2008), p. 679-682 
    ISSN: 1013-9826
    Source: Scientific.Net: Materials Science & Technology / Trans Tech Publications Archiv 1984-2008
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes: A modified starch was employed to be the pore former in the in-situ consolidation formingprocess of porous alumina ceramic. In order to prepare ceramic slurry with high dispersion, highstabilization and high solid volume loading, the effects of modified starch content, dispersant content,alumina solid volume loading, pH value of the slurry and ball milling time on the rheological behavior ofalumina ceramic slurry were investigated. The results indicated that the viscosity of the slurry increasedwith the modified starch content, alumina solid volume loading and ball milling time. When the pH valueof the slurry was 9.0, the modified starch-alumina slurry exhibited high fluidity. The modifiedstarch-alumina slurry was a pseudoplastic fluid exhibiting shear thinning behavior. The slurry possessed adesirable plasticity to enable shape forming when adding 50 vol% modified starch and 1.0 wt% dispersantto the alumina slurry at pH 9.0 after 14 h ball milling treatment
    Type of Medium: Electronic Resource
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
  • 7
    Electronic Resource
    Electronic Resource
    s.l. ; Stafa-Zurich, Switzerland
    Key engineering materials Vol. 353-358 (Sept. 2007), p. 730-734 
    ISSN: 1013-9826
    Source: Scientific.Net: Materials Science & Technology / Trans Tech Publications Archiv 1984-2008
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes: The microstructure characteristic and wear behavior of the severe deformation surfaceconstitution of Ti-4Al-2V alloy were studied in this paper. The results show that the wear resistanceof the deformed surface is much better than that of the coarse grain surface. And the wear mechanismof the nanocrystalline surface is different from that of the coarse grain surface. The former is particlewear mechanism of harder material and the latter is adherence wear mechanism. The influence factorson the wear resistance of the nanocrystalline surface have been discussed
    Type of Medium: Electronic Resource
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
  • 8
    Electronic Resource
    Electronic Resource
    s.l. ; Stafa-Zurich, Switzerland
    Advanced materials research Vol. 26-28 (Oct. 2007), p. 293-296 
    ISSN: 1662-8985
    Source: Scientific.Net: Materials Science & Technology / Trans Tech Publications Archiv 1984-2008
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes: To improve the wear resistance of high chromium white cast iron under severe abrasiveconditions, a composites layer was designed for wear surface, which were locally reinforced with WCparticles. And the local composites were successfully fabricated by optimized centrifugal castingprocess. Then the interface between WC and iron matrix was analyzed with scanning electronmicroscopy (SEM), energy-dispersive X-ray spectroscopy (EDX) and X-ray diffraction (XRD). Andthree body wear tests were carried out on a self-made rig to investigate the wear resistance of thecomposites. For comparison, the wear tests of high chromium white cast iron were also carried outunder the same conditions. The results show that: There are no defects such as inclusion, crack, gaspore and so on in the obtained composites layer, which with a uniform thickness of 10 mm. WCparticles are homogeneously distributed in the composites layer and tightly bonded with the ironmatrix. The WC particles are partially dissolved in the iron matrix during centrifugal casting. Theelements W, C and Fe react to form new carbides such as Fe3W3C or M23C6, which precipitate aroundformer WC particles during subsequent solidification. So the interface between WC particles and theiron matrix is a strong metallurgical bonding. WC particles in the composites layer can effectivelyresist cutting by the abrasive, and then protect the matrix. The wear resistance of the composites layeris 7.23 times of that of high chromium cast iron
    Type of Medium: Electronic Resource
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
  • 9
    Electronic Resource
    Electronic Resource
    s.l. ; Stafa-Zurich, Switzerland
    Advanced materials research Vol. 33-37 (Mar. 2008), p. 795-800 
    ISSN: 1662-8985
    Source: Scientific.Net: Materials Science & Technology / Trans Tech Publications Archiv 1984-2008
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes: This paper utilizes Genetic Programming(GP) and Genetic Algorithm(GA) to analyzeexperiment data. The purpose of this research is to establish a function model of the data. The coremethodology of this research is using GP to get the approximate model first, and then optimizes theparameters and enhance the fitness value of the model by using GA. To validate this method, twoexamples are given: one is the reconstruction of permeability-strain equation of the rock inliterature[1]; another example is the function search automatically of the wire cable isolatorexperiment data. In the process of programming of parse tree, this paper adopted a new way thatdifferent from three traditional methods, the parse tree is described by matrix of special size, moresignificantly, this new method makes the genetic operation of crossover and mutation intuitionstic,even the pellucid Matlab programming language could implement it
    Type of Medium: Electronic Resource
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
  • 10
    Electronic Resource
    Electronic Resource
    s.l. ; Stafa-Zurich, Switzerland
    Key engineering materials Vol. 304-305 (Feb. 2006), p. 236-240 
    ISSN: 1013-9826
    Source: Scientific.Net: Materials Science & Technology / Trans Tech Publications Archiv 1984-2008
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes: Visible waviness on the ball bearing’s outer ring groove, which processed by groove grinder, results in a lower precision of post processing. To reduce the waviness, some experiments are conducted to analyze the property of grinder structure. Accord to analysis result, a modification scheme is provided. In scheme an equilibrant device is designed on the grinding wheel shaft, and rotation of grinding wheel shaft with equilibrant device is simulated with the MSC.visualNastransoftware
    Type of Medium: Electronic Resource
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
Close ⊗
This website uses cookies and the analysis tool Matomo. More information can be found here...