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  • 1
    Electronic Resource
    Electronic Resource
    The NCBI dbGaP database of genotypes and phenotypes (2007)
    [s.l.] : Nature Publishing Group
    Nature genetics 39 (2007), S. 1181-1186 
    Details
    ISSN: 1546-1718
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Medicine
    Notes: [Auszug] The technical advances and declining costs of high-throughput genotyping afford investigators fresh opportunities to do increasingly complex analyses of genetic associations with phenotypic and disease characteristics. The leading candidates for such genome-wide association studies (GWAS) are ...
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1038/ng1007-1181
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  • 2
    Electronic Resource
    Electronic Resource
    Design and fabrication of CAP scaffolds by indirect solid free form fabrication (2005)
    Bingley : Emerald
    Rapid prototyping journal 11 (2005), S. 312-318 
    Details
    ISSN: 1355-2546
    Source: Emerald Fulltext Archive Database 1994-2005
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes: Purpose - To fabricate the self-hardening calcium phosphate composite scaffolds with controlled internal pore architectures using rapid prototyping (RP) techniques and investigate their in vitro bone tissue engineering responses. Design/methodology/approach - The three-dimensionally interconnected pores in scaffolds can facilitate sufficient supply of blood, oxygen and nutrients for the ingrowth of bone cells, tissue regeneration, and vascularization. It is essential for bone tissue engineering to provide an accurate control over the scaffolds material, porosity, and internal pore architectures. Negative image of scaffold was designed and epoxy resin molds were fabricated on sterolithography apparatus. Calcium phosphate cement slurry was cast in these molds. After self-hardening, the molds were removed by pyrolysis and the resulting scaffolds were obtained. Findings - Eight scaffolds with 54.45 percent porosity were tested on an Instron machine. The average compressive strength measured was 5.8±0.8?Mpa. Cytotoxicity and cell proliferation studies were conducted with rabbit osteoblast. Results showed that these scaffolds were non-toxic and displayed excellent cell growth during the 2 weeks of in vitro culture. Research limitations/implications - The resulting scaffolds inherited errors and defects from the molds, such as cracks and dimensional changes. Originality/value - The present method enhances the versatility of scaffold fabrication by RP. It is capable of reproducibly fabricating scaffolds from a variety of biomaterials.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1108/13552540510623639
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  • 3
    Electronic Resource
    Electronic Resource
    Study on Two-Phase Nanocrystalline Nd〈sub〉2〈/sub〉Fe〈sub〉14〈/sub〉B/α-Fe Bonded Magnet (2005)
    s.l. ; Stafa-Zurich, Switzerland
    Materials science forum Vol. 475-479 (Jan. 2005), p. 2165-2168 
    Details
    ISSN: 1662-9752
    Source: Scientific.Net: Materials Science & Technology / Trans Tech Publications Archiv 1984-2008
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes: Two-phase nanocrystalline ribbons were prepared by melt-spun and subsequent heat treatment. Excellent magnetic properties of the bonded magnet were achieved as follows: Br = 0.67 T, JHc = 664.3 kA·m-1, (BH) max = 75.0 kJ·m-3. The mean grain size of the ribbons heat-treated at 710 ℃/ 4 min is about 50 nm. After heat-treated the ribbons at 750 ℃/ 4 min, the mean grain size is about 100 nm
    Type of Medium: Electronic Resource
    URL: http://www.tib-hannover.de/fulltexts/2011/0528/02/09/transtech_doi~10.4028%252Fwww.scientific.net%252FMSF.475-479.2165.pdf
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  • 4
    Electronic Resource
    Electronic Resource
    Study on Sputtering Characteristics of Ni80Cr20 Alloy Target (2007)
    s.l. ; Stafa-Zurich, Switzerland
    Key engineering materials Vol. 353-358 (Sept. 2007), p. 1891-1894 
    Details
    ISSN: 1013-9826
    Source: Scientific.Net: Materials Science & Technology / Trans Tech Publications Archiv 1984-2008
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes: Sputtering rate Sr was proposed as an alternative parameter instead of sputtering yield Yto calibrate the sputtering ability of the target, defined as the mass loss of the target per unit timeand sputtering current. The approach is more reliable for glow discharge processes since the intensebackscattering effect was taken into consideration. The effects of processing parameters on Sr wereinvestigated through orthogonal test, the results indicated that target temperature affects Srobviously, and among the discharge parameters, the target voltage and discharge pressure were thegoverning factors. Through regression analysis, the sputtering rate Sr was expressed as a function ofsputtering voltage and discharge pressure which could be used to evaluate or predict the real outputof the sputtering target
    Type of Medium: Electronic Resource
    URL: http://www.tib-hannover.de/fulltexts/2011/0528/01/55/transtech_doi~10.4028%252Fwww.scientific.net%252FKEM.353-358.1891.pdf
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  • 5
    Electronic Resource
    Electronic Resource
    Experimental Study of Microelectrode Array and Micro-Hole Array Fabricated by Ultrasonic Enhanced Micro-EDM (2007)
    s.l. ; Stafa-Zurich, Switzerland
    Key engineering materials Vol. 364-366 (Dec. 2007), p. 482-487 
    Details
    ISSN: 1013-9826
    Source: Scientific.Net: Materials Science & Technology / Trans Tech Publications Archiv 1984-2008
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes: Micro electrical discharge machining (EDM), enhanced with ultrasonic vibration, isexplored and assessed as a method for developing microelectrode array, for microelectrode arrayfabricated by LIGA has shortcomings such as complex technology and high price. Based on themechanism of micro-EDM, micro-hole array discharges to fabricate microelectrode array by reversecopying. In the process of reverse copying, the thicker rod electrode can not rotate, resulting inelectric arc and short-circuit occurring easily, so it is necessary to add ultrasonic vibration on theplane plate electrode, in order to exclude debris as soon as possible and stabilize machining process.In the process of machining, four parameters, such as working voltage, working capacity, ultrasonicamplitude and holes spacing, are important to machining efficiency, each parameter has four typicalvalues. In order to reduce experiment times, a scheme of orthogonal experiment was designed withdifferent parameters combination. With result of experiments, the ratio of mean square deviation toerror mean square deviation of each parameter was calculated and significance of each parameterwas obtained, and the best parameters combination was asserted through theoretical calculation.Also, experimental study of using microelectrode array to machine micro-hole array by Micro-EDM was made and influence curve of each parameter was drawn. Finally, 5×5 arrays ofmicroelectrode were obtained, the diameter of single electrode is less than about 30.m and heightto-width aspect ratios is more than 8, moreover, these microelectrode arrays have good coaxialityand surface quality
    Type of Medium: Electronic Resource
    URL: http://www.tib-hannover.de/fulltexts/2011/0528/01/56/transtech_doi~10.4028%252Fwww.scientific.net%252FKEM.364-366.482.pdf
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  • 6
    Electronic Resource
    Electronic Resource
    Study on the Influence Factors of Electrochemical Micromachining (2007)
    s.l. ; Stafa-Zurich, Switzerland
    Key engineering materials Vol. 364-366 (Dec. 2007), p. 903-908 
    Details
    ISSN: 1013-9826
    Source: Scientific.Net: Materials Science & Technology / Trans Tech Publications Archiv 1984-2008
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes: There are many influence factors of electrochemical micromachining (EMM)development. So the characteristics of EMM technology were analyzed firstly. It was an effectivemethod that the nanosecond pulses voltage was used in EMM, and the nanosecond pulses voltagewas prepared to solve the problems of machining area, using small gap, and machining micro 3Dstructure. Its minimum pulse duration is 5ns, and its voltage, current, and duty ratio can be changedfreely. Moreover, many experiments of EMM were carried into execution. After the phenomenonand results of the experiments were analyzed, the reformative project of experiment was putforward. The feasibility of the project and technique route was testified correctly by the nanosecondpulses voltage on the multifunction machine tool which was manufactured independently. Afterstudying on the influences of EMM technology, the experiences of EMM process will be enrichedand make EMM have a further development
    Type of Medium: Electronic Resource
    URL: http://www.tib-hannover.de/fulltexts/2011/0528/01/56/transtech_doi~10.4028%252Fwww.scientific.net%252FKEM.364-366.903.pdf
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  • 7
    Electronic Resource
    Electronic Resource
    Residual Stress and Stability of Thermal Barrier Coatings during Cyclic Thermal Loading (2008)
    s.l. ; Stafa-Zurich, Switzerland
    Key engineering materials Vol. 368-372 (Feb. 2008), p. 1344-1346 
    Details
    ISSN: 1013-9826
    Source: Scientific.Net: Materials Science & Technology / Trans Tech Publications Archiv 1984-2008
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes: The residual stress accumulation of thermal barrier coatings (TBC) during thermal cycling hasbeen simulated by thermal elastic-plastic finite element method. Stability process of thermal barriercoatings during thermal cycling is studied by Melan's static shakedown theorem considering thermalgradients and thermal expansion misfit. The influences of the interfacial morphology of top coat / bondcoat (TC/BC) on residual stress and stability process are analyzed. Thus, the residual stress and stabilityprocess are affected remarkably by interfacial topography between TC and BC. Accidented interfacecause the sudden change of the interfacial residual stress which is harmful to interface bonding intensityand stabilization. It is useful information for studying of the life and final spallation of TBC system
    Type of Medium: Electronic Resource
    URL: http://www.tib-hannover.de/fulltexts/2011/0528/01/56/transtech_doi~10.4028%252Fwww.scientific.net%252FKEM.368-372.1344.pdf
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  • 8
    Electronic Resource
    Electronic Resource
    A Cutting Process Parameter Optimization Expert System for Difficult-to-Cut Materials (2008)
    s.l. ; Stafa-Zurich, Switzerland
    Key engineering materials Vol. 375-376 (Mar. 2008), p. 574-577 
    Details
    ISSN: 1013-9826
    Source: Scientific.Net: Materials Science & Technology / Trans Tech Publications Archiv 1984-2008
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes: Focusing on the machining complexity of large containers where difficult-to-cutmaterials are used a lot, a cutting process parameter optimization expert system for difficult-to-cutmaterials is constructed based on experts’ knowledge and computer soft wares (VC++ 6.0and SQLServer 2000). In this paper, we made construction analysis and module design for the expert system,then constructed the knowledge base according to certain constraint models, and realized thefunctions of every module of the expert system by using the forward inference. This expert systemcan play a scientific direction role in the process parameters selection for cutting large containers
    Type of Medium: Electronic Resource
    URL: http://www.tib-hannover.de/fulltexts/2011/0528/01/57/transtech_doi~10.4028%252Fwww.scientific.net%252FKEM.375-376.574.pdf
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  • 9
    Electronic Resource
    Electronic Resource
    The Key Techniques of Novel Miniaturized Ultrasonic Motor and its Application in Micro-EDM (2008)
    s.l. ; Stafa-Zurich, Switzerland
    Key engineering materials Vol. 375-376 (Mar. 2008), p. 77-81 
    Details
    ISSN: 1013-9826
    Source: Scientific.Net: Materials Science & Technology / Trans Tech Publications Archiv 1984-2008
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes: In order to operate in narrow space, a novel miniaturized EDM (Electro DischargeMachining) mechanism has been developed. A prototype of miniaturized EDM device based onultrasonic motor (UM) has been developed, which has its advantage of compact size (70×40×50 mm).The differential driving electrode has been presented, and coaxial forced vibration of electrode isbenefit for the evacuation of debris, so it helps to achieve stable and efficient machining. Drivingprinciple of ultrasonic motor is analyzed, and simulation using Finite Element Method (FEM) isaccomplished. The auto-frequency tracking has been carried out, in order that the motor work onresonant or quasi-resonant frequency. Finally, EDM experiment has been finished, and holes withfigures of circleΦ85μm and Y-typed have been machined
    Type of Medium: Electronic Resource
    URL: http://www.tib-hannover.de/fulltexts/2011/0528/01/57/transtech_doi~10.4028%252Fwww.scientific.net%252FKEM.375-376.77.pdf
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  • 10
    Electronic Resource
    Electronic Resource
    Experiment Study of Combining Micro EDM with USM (2008)
    s.l. ; Stafa-Zurich, Switzerland
    Key engineering materials Vol. 375-376 (Mar. 2008), p. 248-252 
    Details
    ISSN: 1013-9826
    Source: Scientific.Net: Materials Science & Technology / Trans Tech Publications Archiv 1984-2008
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes: Experiments of combining micro EDM with USM are carried out to enhance themachining ability and flexibility of the micro EDM, improve the machining state, and increase theproductivity and aspect ratio of the micro holes. Basing on RC pulse power supply and workpiecevibration, the micro holes are drilled. The results of comparing experiments indicate that in theprocesses of both micro EDM without USM and micro EDM with USM, the machining velocityand the wear of the electrode increase with the increase of open voltage and loop capacitance. Theexperiment results of amplitude influencing on the machining process indicate that with the increaseof ultrasonic amplitude, the machining velocity heightens and the aspect ratio of the micro holesaugments; at the same time, however, the wear of the electrode and the extensive magnitude of theholes increase. Micro holes with some cross-section and accurate profile are drilled steadily
    Type of Medium: Electronic Resource
    URL: http://www.tib-hannover.de/fulltexts/2011/0528/01/57/transtech_doi~10.4028%252Fwww.scientific.net%252FKEM.375-376.248.pdf
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