Publication Date:
2005-06-18
Description:
Activity in several areas of the human brain and the monkey brain increases when a subject anticipates events associated with a reward, implicating a role for bias of decision and action. However, in real life, events do not always appear as expected, and we must choose an undesirable action. More than half of the neurons in the monkey centromedian (CM) thalamus were selectively activated when a small-reward action was required but a large-reward option was anticipated. Electrical stimulation of the CM after a large-reward action request substituted a brisk performance with a sluggish performance. These results suggest involvement of the CM in a mechanism complementary to decision and action bias.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Minamimoto, Takafumi -- Hori, Yukiko -- Kimura, Minoru -- New York, N.Y. -- Science. 2005 Jun 17;308(5729):1798-801.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Department of Physiology, Kyoto Prefectural University of Medicine, Kawaramachi-Hirokoji, Kamigyo-ku, Kyoto 602-8566, Japan.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/15961671" target="_blank"〉PubMed〈/a〉
Keywords:
Animals
;
Behavior, Animal
;
Decision Making
;
Electric Stimulation
;
Electrophysiology
;
Macaca
;
Neurons/*physiology
;
Probability
;
Reaction Time
;
*Reward
;
Task Performance and Analysis
;
Thalamic Nuclei/*physiology
Print ISSN:
0036-8075
Electronic ISSN:
1095-9203
Topics:
Biology
,
Chemistry and Pharmacology
,
Computer Science
,
Medicine
,
Natural Sciences in General
,
Physics
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