ISSN:
1573-0832
Source:
Springer Online Journal Archives 1860-2000
Topics:
Biology
,
Medicine
Notes:
Summary Although occasional hibernation was observed in golden hamsters kept at low temperatures during the winter months, the periods of hibernation were apparently too short to induce conversion of the yeast cells ofH. capsulatum into the mycelial phase or to prevent conversion into the yeast phase when inoculated in the mycelial phase. As a result of exposure to low temperatures, a heavily disseminated, severe and often fatal histoplasmosis was observed in contrast to slight dissemination in control animals kept at room temperature. In addition to extensive lesions in the organs in the heavily infected hamsters, severe fungemia, accumulations of numerous yeast cells within large cells and histoplasmic phlebitis and pleuritis of a proliferative character were seen. Schaumann bodies did not develop in granulomatous lesions of heavily infected animals kept at low temperatures, nor were they prominent in tissues with heavy accumulations of yeast cells or after inoculation with the mycelial phase.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF02053786
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