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  • 27.70.+q  (1)
  • Biological Evolution  (1)
  • Langevin distribution  (1)
  • Microglia/*metabolism  (1)
  • 2005-2009  (1)
  • 1990-1994  (2)
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  • 1
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    A human-specific gene in microglia (2005)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 2005-09-10
    Description: Recent studies have shown multiple differences between humans and apes in sialic acid (Sia) biology, including Siglecs (Sia-recognizing-Ig-superfamily lectins). Comparisons with the chimpanzee genome indicate that human SIGLEC11 emerged through human-specific gene conversion by an adjacent pseudogene. Conversion involved 5 cent untranslated sequences and the Sia-recognition domain. This human protein shows reduced binding relative to the ancestral form but recognizes oligosialic acids, which are enriched in the brain. SIGLEC11 is expressed in human but not in chimpanzee brain microglia. Further studies will determine if this event was related to the evolution of Homo.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Hayakawa, Toshiyuki -- Angata, Takashi -- Lewis, Amanda L -- Mikkelsen, Tarjei S -- Varki, Nissi M -- Varki, Ajit -- R01GM32373/GM/NIGMS NIH HHS/ -- New York, N.Y. -- Science. 2005 Sep 9;309(5741):1693.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Glycobiology Research and Training Center, University of California at San Diego, La Jolla, CA 92093, USA.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/16151003" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Biological Evolution ; Brain/*metabolism ; Exons ; *Gene Conversion ; Humans ; Lectins/*genetics/metabolism ; Membrane Proteins/*genetics/metabolism ; Microglia/*metabolism ; Pan troglodytes/genetics/metabolism ; Phylogeny ; Pongo pygmaeus/genetics/metabolism ; Pseudogenes ; Regulatory Sequences, Nucleic Acid ; Sialic Acids/metabolism
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
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  • 2
    Electronic Resource
    Electronic Resource
    On tests for the mean direction of the Langevin distribution (1990)
    Springer
    Annals of the Institute of Statistical Mathematics 42 (1990), S. 359-373 
    Details
    ISSN: 1572-9052
    Keywords: Asymptotic expansion ; central limit theorem ; Langevin distribution ; likelihood ratio criterion ; Watson statistic ; Rao statistic ; modified Wald statistic
    Source: Springer Online Journal Archives 1860-2000
    Topics: Mathematics
    Notes: Abstract The asymptotic expansions of the distribution of a sum of independent random vectors with Langevin distribution are given. The power functions of the likelihood ratio criterion, Watson statistic, Rao statistic and the modified Wald statistic for testing the hypothesis of the mean direction are obtained asymptotically and a numerical comparison is made.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00050842
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    Paper (German National Licenses)
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  • 3
    Electronic Resource
    Electronic Resource
    Level structure of doubly odd154Ho (1994)
    Springer
    The European physical journal 350 (1994), S. 89-90 
    Details
    ISSN: 1434-601X
    Keywords: 23.20.Lv ; 27.70.+q
    Source: Springer Online Journal Archives 1860-2000
    Topics: Physics
    Notes: Abstract 154Ho was studied via141Pr(16O,3n) reaction at beam energy of 75 MeV. We found two new rotationally aligned bands made of neutron h9/2 and f7/2 orbitals coupled to a proton h11/2 orbital. As with several new high-spin states, up to I=20, the ground state band with odd parity starts to show anomalous signature splitting at I=13 in this doubly odd154Ho. The observed rotational bands in154Ho are quite consistent with the onset of collectivity which appears in general at neutron number of 87 in neutron-deficient rare-earth nuclei.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01290672
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