ISSN:
1612-1112
Keywords:
Column liquid chromatography
;
Chiral separations
;
Chymotrypsin on silica
;
Amino acids
Source:
Springer Online Journal Archives 1860-2000
Topics:
Chemistry and Pharmacology
Notes:
Summary A new HPLC stationary phase was synthesized by the covalent immobilization of α-chymotrypsin on silica. This increased the stability of the enzyme, without decreasing its activity. The initial chromatographic studies show that this phase can be used for chiral separations of enantiomeric solutes. The stereochemical resolutions of amino acids and amino acid derivatives are reported.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF02311427
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