Publikationsdatum:
2014-09-10
Beschreibung:
Article Candidaemia is a common cause of bloodstream infection, but the genetic basis of Candida infection is poorly understood. Here, the authors identify genetic variation at three loci that increase risk of candidaemia, and show that genes at these loci have a role in antifungal host defence. Nature Communications doi: 10.1038/ncomms5675 Authors: Vinod Kumar, Shih-Chin Cheng, Melissa D. Johnson, Sanne P Smeekens, Agnieszka Wojtowicz, Evangelos Giamarellos-Bourboulis, Juha Karjalainen, Lude Franke, Sebo Withoff, Theo S Plantinga, Frank L. van de Veerdonk, Jos W.M. van der Meer, Leo A.B. Joosten, Harry Sokol, Hermann Bauer, Bernhard G. Herrmann, Pierre-Yves Bochud, Oscar Marchetti, John R. Perfect, Ramnik J. Xavier, Bart Jan Kullberg, Cisca Wijmenga, Mihai G. Netea
Digitale ISSN:
2041-1723
Thema:
Biologie
,
Chemie und Pharmazie
,
Allgemeine Naturwissenschaft
,
Physik
Permalink