Publication Date:
2013-09-19
Description:
Two new naphthoquinones, (2 R )-6,8-dihydroxy- α -dunnione ( 1 ), 6,8-dihydroxy-2,7-dimethoxy-3-(1,1-dimethylprop-2-enyl)-1,4-naphthoquinone ( 2 ), together with three known compounds, (2 R )-6,8-dihydroxy-7-methoxy- α -dunnione ( 3 ), nevadensin ( 4 ), and lysioside C ( 5 ), were isolated from the whole plant of Lysionotus pauciflorus. Their structures were established by spectroscopic methods. Hydroxylated naphthoquinones are reported to occur in a Lysionotus species for the first time. The cytotoxic activities of compounds 1 – 3 were evaluated in vitro against a panel of tumor cell lines.
Print ISSN:
0018-019X
Electronic ISSN:
1522-2675
Topics:
Chemistry and Pharmacology
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