ALBERT

Description: After an initial stone episode persons are at increased risk for future stone formation. A systematic approach is required to monitor the efficacy of treatment and preventive measures, and to assess the risk of developing new stones. This is important for persons working in critical jobs or austere environments, such as astronauts. A literature review of the current standards of care for renal stone monitoring and imaging was done. Military and civil aviation standards were also reviewed, as well as the medical precedents from the space program. Additionally, a new, more effective, renal stone ultrasound protocol has been developed. Using this work, a monitoring algorithm was proposed that takes into consideration the unique mission and operational environment of spaceflight. The approach to imaging persons with history of renal stones varies widely in the literature. Imaging is often done yearly or biannually, which may be too long for mission critical personnel. In the proposed algorithm astronauts with a history of renal stone, who may be under consideration for assignment, are imaged by a detailed, physiciandriven, ultrasound protocol. Unassigned personnel are monitored by yearly ultrasound and urine studies. Any positive ultrasound study is then followed by low-dose renal computed tomography scan. Other criteria are also established. The proposed algorithm provides a balanced approach between efficacy and reduced radiation exposure for the monitoring of astronauts with a renal stone history. This may eventually allow a transition from a risk-averse, to a risk-modifying approach that can enable continued service of individuals with history of renal stone that have adequately controlled risk factors.

Description: There are no specific guidelines for the management of renal stones in astronauts. Given the increased risk for bone loss, hypercalcuria, and stone formation due to microgravity, a clinical practice guideline is needed. Methods An extensive review of the literature and current aeromedical standards for the management of renal stones was done. The NASA Flight Medicine Clinic's electronic medical record and Longitudinal Survey of Astronaut Health were also reviewed. This information was used to create an algorithm for the management of renal stones in astronauts. Results Guidelines are proposed based on accepted standards of care, with consideration to the environment of spaceflight. In a usual medical setting, asymptomatic, small stones less than 7 mm are often observed over time. Given the constraints of schedule, and the risks to crew health and mission, this approach is too liberal. An upper limit of 3 mm stone diameter was adopted before requiring intervention, because this is the largest size that has a significant chance of spontaneous passage on its own. Other specific guidelines were also created. Discussion The spaceflight environment requires more aggressive treatment than would otherwise be found with the usual practice of medicine. A small stone can become a major problem because it may ultimately require medical evacuation from orbit. Thus renal stones are a significant mission threat and should be managed in a systematic way to mitigate risks to crew health and mission success.

Description: On 27 February 2010 the Mw 8.8 Maule earthquake in Central Chile ruptured a seismic gap where significant strain had accumulated since 1835. The postseismic phase was monitored by a network of temporary seismic stations (IMAD) and GPS stations along and around the whole rupture zone. Here, we examine the relation between the spatial-temporal properties of the aftershock distribution and postseismic displacements from GPS. Using scaling relations derived from global data, we calculate the slip and size of individual aftershocks and relate these to preliminary afterslip models. Events larger than Mw=5 result in slip of more than _20 cm and some of these events presumably exceed locally the cumulative afterslip from 2 months period. Along the whole rupture the small patches ruptured by the aftershocks do not fill up the whole rupture, which is reflected by the observation that the cumulative moment of aftershock seismicity is significantly smaller than the total moment released by afterslip. The time-series of Earth’s surface postseismic displacements analyzed here show rapid transient deformation immediately following the Maule earthquake. Results show a first order linear relationship between cumulative displacement with the cumulative number of aftershocks. Similar relations have been observed for other earthquakes. This indicates that both processes decay obeying a similar physical law. Due to the higher number of GPS stations along the Maule 2010 rupture the ratio of displacement (afterslip) per aftershock event might allow to infer rheological properties when mapped along the rupture zone. Furthermore, we discuss the relation between the azimuths of co-seismic, interseismic and postseismic displacement vectors and compare these with the strike directions of focal mechanisms. We compare the results from the Maule 2010 rupture area with the 2005 Nias and the 2011 Tohoku-Oki earthquakes.

Description: On 27 February 2010 the Mw 8.8 Maule earthquake in Central Chile ruptured a seismic gap where significant strain had accumulated since 1835. Shortly after the mainshock a dense network of temporary seismic stations was installed along the whole rupture zone in order to capture the aftershock activity. Here, we present the aftershock distribution and first motion polarity focal mechanisms based on automatic detection algorithms and picking engines. By processing the seismic data between 15 March and 30 September 2010 from stations from IRIS, IPGP, GFZ and University of Liverpool we determined 20,205 hypocentres with magnitudes Mw between 1 and 5.5. Seismic activity occurs in six groups: 1.) Normal faulting outer rise events 2.) A shallow group of plate interface seismicity apparent at 25–35 km depth and 50–120 km distance to the trench with some variations between profiles. Along strike, the aftershocks occur largely within the zone of coseismic slip but extend ~50 km further north, and with predominantly shallowly dipping thrust mechanisms. Along dip, the events are either within the zone of coseismic slip, or downdip from it, depending on the coseismic slip model used. 3.) A third band of seismicity is observed further downdip at 40–50 km depth and further inland at 150–160 km trench perpendicular distance, with mostly shallow dipping (~28°) thrust focal mechanisms indicating rupture of the plate interface significantly downdip of the coseismic rupture, and presumably above the intersection of the continental Moho with the plate interface. 4.) A deep group of intermediate depth events between 80 and 120 km depth is present north of 36°S. Within the Maule segment, a large portion of events during the inter-seismic phase originated from this depth range. 5.) The magmatic arc exhibits a small amount of crustal seismicity but does not appear to show significantly enhanced activity after the Mw 8.8 Maule 2010 earthquake. 6.) Pronounced crustal aftershock activity with mainly normal faulting mechanisms is found in the region of Pichilemu (~34.5°S). These crustal events occur in a ~30 km wide region with sharp inclined boundaries and oriented oblique to the trench. The best-located events describe a plane dipping to the southwest, consistent with one of the focal planes of the large normal-faulting aftershock (Mw=6.9) on 11 March 2010.

Description: On 27 February 2010 the Mw 8.8 Maule earthquake in Central Chile ruptured a seismic gap where significant strain had accumulated since 1835. Shortly after the mainshock a dense network of temporary seismic landstations was installed along the whole rupture zone in order to capture the aftershock activity. We present the aftershock distribution and first motion polarity focal mechanisms based on automatic detection algorithms and picking engines. Processing the seismic data between 15 March and 30 September 2010 from stations from IRIS, IPGP, Caltech and GFZ, we determined 19,908~hypocentres with magnitudes Mw between 1 and 6.2. Seismic activity occurs in six groups: 1.) Normal faulting outer rise events 2.) A shallow group of plate interface seismicity apparent at 25-35 km depth and 50-120 km distance to the trench. Along strike, the aftershocks occur largely within the zone of co-seismic slip but extend ~50 km further north. Along dip, the events are either within the zone of co-seismic slip, or downdip from it, depending on the slip model used. 3.) A third band of seismicity is observed further downdip at 40-50 km depth and further inland at 150-160 km trench perpendicular distance, with mostly shallow dipping thrust focal mechanisms indicating rupture of the plate interface significantly downdip of the co-seismic rupture, and presumably above the intersection of the continental Moho with the plate interface. 4.) A deep group of intermediate depth events between 80 to 120 km depth are present north of 36°S. 5.) The magmatic arc exhibits a small amount of crustal seismicity but does not appear to show significantly enhanced activity after the mainshock 6.) Pronounced crustal aftershock activity is found in the region of Pichilemu (~34.5°S). The time-series of postseismic deformation analyzed here show rapid transient deformation immediately following the Maule earthquake. We examine the relation between the spatial-temporal properties of the aftershock distribution and postseismic displacements from GPS. First results show a linear relationship between cumulative displacement and cumulative number of aftershocks at large times (〉25d, when the local aftershock catalog is available). This relationship may be use to infer rheological properties. Similar relations have been observed in other large subduction zone earthquakes.