ALBERT

All Library Books, journals and Electronic Records Telegrafenberg

X
feed icon rss

Your email was sent successfully. Check your inbox.

An error occurred while sending the email. Please try again.

Proceed reservation?

Export
Filter
  • Feature Articles  (10)
  • 04. Solid Earth::04.06. Seismology::04.06.04. Ground motion  (9)
  • National Academy of Sciences  (10)
  • Springer  (8)
  • WILEY-BLACKWELL  (1)
  • 2010-2014  (19)
Collection
Keywords
Publisher
Years
Year
  • 1
    facet.materialart.
    Unknown
    Hunter-gatherer genomic diversity suggests a southern African origin for modern humans [Genetics] (2011)
    National Academy of Sciences
    Details
    Publication Date: 2011-03-30
    Description: Africa is inferred to be the continent of origin for all modern human populations, but the details of human prehistory and evolution in Africa remain largely obscure owing to the complex histories of hundreds of distinct populations. We present data for more than 580,000 SNPs for several hunter-gatherer populations: the Hadza and Sandawe of Tanzania, and the ≠Khomani Bushmen of South Africa, including speakers of the nearly extinct N|u language. We find that African hunter-gatherer populations today remain highly differentiated, encompassing major components of variation that are not found in other African populations. Hunter-gatherer populations also tend to have the lowest levels of genome-wide linkage disequilibrium among 27 African populations. We analyzed geographic patterns of linkage disequilibrium and population differentiation, as measured by FST, in Africa. The observed patterns are consistent with an origin of modern humans in southern Africa rather than eastern Africa, as is generally assumed. Additionally, genetic variation in African hunter-gatherer populations has been significantly affected by interaction with farmers and herders over the past 5,000 y, through both severe population bottlenecks and sex-biased migration. However, African hunter-gatherer populations continue to maintain the highest levels of genetic diversity in the world.
    Keywords: Feature Articles
    Print ISSN: 0027-8424
    Electronic ISSN: 1091-6490
    Topics: Biology , Medicine , Natural Sciences in General
    Published by National Academy of Sciences
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    PAPER CURRENT
  • 2
    facet.materialart.
    Unknown
    A yeast functional screen predicts new candidate ALS disease genes [Neuroscience] (2011)
    National Academy of Sciences
    Details
    Publication Date: 2011-12-28
    Description: Amyotrophic lateral sclerosis (ALS) is a devastating and universally fatal neurodegenerative disease. Mutations in two related RNA-binding proteins, TDP-43 and FUS, that harbor prion-like domains, cause some forms of ALS. There are at least 213 human proteins harboring RNA recognition motifs, including FUS and TDP-43, raising the possibility that additional RNA-binding proteins might contribute to ALS pathogenesis. We performed a systematic survey of these proteins to find additional candidates similar to TDP-43 and FUS, followed by bioinformatics to predict prion-like domains in a subset of them. We sequenced one of these genes, TAF15, in patients with ALS and identified missense variants, which were absent in a large number of healthy controls. These disease-associated variants of TAF15 caused formation of cytoplasmic foci when expressed in primary cultures of spinal cord neurons. Very similar to TDP-43 and FUS, TAF15 aggregated in vitro and conferred neurodegeneration in Drosophila, with the ALS-linked variants having a more severe effect than wild type. Immunohistochemistry of postmortem spinal cord tissue revealed mislocalization of TAF15 in motor neurons of patients with ALS. We propose that aggregation-prone RNA-binding proteins might contribute very broadly to ALS pathogenesis and the genes identified in our yeast functional screen, coupled with prion-like domain prediction analysis, now provide a powerful resource to facilitate ALS disease gene discovery.
    Keywords: Feature Articles
    Print ISSN: 0027-8424
    Electronic ISSN: 1091-6490
    Topics: Biology , Medicine , Natural Sciences in General
    Published by National Academy of Sciences
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    PAPER CURRENT
  • 3
    facet.materialart.
    Unknown
    Role of the ubiquitin-like protein Urm1 as a noncanonical lysine-directed protein modifier [Cell Biology] (2011)
    National Academy of Sciences
    Details
    Publication Date: 2011-02-02
    Description: The ubiquitin (Ub)-related modifier Urm1 functions as a sulfur carrier in tRNA thiolation by means of a mechanism that requires the formation of a thiocarboxylate at the C-terminal glycine residue of Urm1. However, whether Urm1 plays an additional role as a Ub-like protein modifier remains unclear. Here, we show that Urm1 is conjugated to lysine residues of target proteins and that oxidative stress enhances protein urmylation in both Saccharomyces cerevisiae and mammalian cells. Similar to ubiquitylation, urmylation involves a thioester intermediate and results in the formation of a covalent peptide bond between Urm1 and its substrates. In contrast to modification by canonical Ub-like modifiers, however, conjugation of Urm1 involves a C-terminal thiocarboxylate of the modifier. We have confirmed that the peroxiredoxin Ahp1 is such a substrate in S. cerevisiae and found that Urm1 targets a specific lysine residue of Ahp1 in vivo. In addition, we have identified several unique substrates in mammalian cells and show that Urm1 targets at least two pathways on oxidant treatment. First, Urm1 is appended to lysine residues of three components that function in its own pathway (i.e., MOCS3, ATPBD3, and CTU2). Second, Urm1 is conjugated to the nucleocytoplasmic shuttling factor cellular apoptosis susceptibility protein. Thus, Urm1 has a conserved dual role by integrating the functions of prokaryotic sulfur carriers with those of eukaryotic protein modifiers of the Ub family.
    Keywords: Feature Articles
    Print ISSN: 0027-8424
    Electronic ISSN: 1091-6490
    Topics: Biology , Medicine , Natural Sciences in General
    Published by National Academy of Sciences
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    PAPER CURRENT
  • 4
    facet.materialart.
    Unknown
    The ITalian ACcelerometric Archive (ITACA): processing of strong-motion data (2011)
    Springer
    Details
    Publication Date: 2012-02-03
    Description: The Italian strong-motion database was created during a joint project between Istituto Nazionale di Geofisica e Vulcanologia (INGV, Italian Institute for Geophysics and Vulcanology) and Dipartimento della Protezione Civile (DPC, Italian Civil Protection). The aim of the project was the collection, homogenization and distribution of strong motion data acquired in Italy in the period 1972–2004 by different institutions, namely Ente Nazionale per l’Energia Elettrica (ENEL, Italian electricity company), Ente per le Nuove tecnologie, l’Energia e l’Ambiente (ENEA, Italian energy and environment organization) and DPC. Recently the strong-motion data relative to the 23th December 2009, Parma (Mw = 5.4 and Mw = 4.9) and to the April 2009 L’Aquila sequences (13 earthquakes with 4.1 ≤ Mw ≤ 6.3) were included in the Italian Accelerometric Archive (ITACA) database (beta release). The database contains 7,038 waveforms from analog and digital instruments, generated by 1.019 earthquakes with magnitude up to 6.9 and can be accessed on-line at the web site http://itaca. mi.ingv.it. The strong motion data are provided in the unprocessed and processed versions. This article describes the steps followed to process the acceleration time series recorded by analogue and digital instruments. The procedures implemented involve: baseline removal, instrumental correction, band pass filtering with acausal filters, integration of the corrected acceleration in order to obtain velocity and displacement waveforms, computation of accel- eration response spectra and strong motion parameters. This procedure is applied to each accelerogram and it is realised to preserve the low frequency content of the records.
    Description: Published
    Description: 1175-1187
    Description: 5.2. TTC - Banche dati di sismologia strumentale
    Description: JCR Journal
    Description: open
    Keywords: Strong motion ; processing ; 04. Solid Earth::04.06. Seismology::04.06.04. Ground motion
    Repository Name: Istituto Nazionale di Geofisica e Vulcanologia (INGV)
    Type: article
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    PAPER (OA)
  • 5
    facet.materialart.
    Unknown
    Italian strong motion database relative to the period 1972–2004: motivations and aims (2011)
    Springer
    Details
    Publication Date: 2017-04-04
    Description: The Italian Accelerometic Archive (ITACA) was created in 2007 during a joint project between the Italian Institute for Geophysics and Vulcanology (Istituto Nazionale di Geofisica e Vulcanologia, INGV) and the Italian Civil Protection (Dipartimento della Protezione Civile, DPC). The project, started in 2006, had the aim of filling the data gap of existing strong motion databases and facilitating strong motion data users in obtaining good quality waveforms, through the collection, homogenization and distribution of strong motion data acquired during the period 1972–2004 in Italy by different institutions (Ente Nazionale per l’Energia Elettrica, ENEL, Italian electricity company; Ente per le Nuove tecnologie, l’Energia e l’Ambiente, ENEA, Italian energy and environment organizationDPC). The compiled database contains 2,182 three-component waveforms generated by 1,008 earthquakes with a maximum moment magnitude of 6.9 (1980 Irpinia earthquake) and can be accessed on-line at the portal denominated ITACAat the site http://itaca.mi.ingv.it,where a wide range of search tools enables the user to interactively retrieve events, recording stations and waveforms with particular characteristics, whose parameters can be specified, as needed, through user friendly interfaces. A range of display options allows users to view data in different contexts, extract and download time series and spectral data. This article describes the state of the art up to 2006 and the activities which led to the completion of the project.
    Description: Published
    Description: 1159-1174
    Description: 5.2. TTC - Banche dati di sismologia strumentale
    Description: JCR Journal
    Description: open
    Keywords: strong motion ; database ; 04. Solid Earth::04.06. Seismology::04.06.04. Ground motion
    Repository Name: Istituto Nazionale di Geofisica e Vulcanologia (INGV)
    Type: article
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    PAPER (OA)
  • 6
    facet.materialart.
    Unknown
    Regression analysis of MCS intensity and ground motion spectral accelerations (SAs) in Italy (2012)
    WILEY-BLACKWELL
    Details
    Publication Date: 2017-04-04
    Description: We present the results of the regression analyses between Mercalli-Cancani-Sieberg (MCS) intensity and the spectral acceleration (SA) at 0.3, 1.0 and 2.0 s (SA03, SA10 and SA20). In Italy, the MCS scale is used to describe the level of ground shaking suffered by manufactures or perceived by the people, and it differs to some extent from the Mercalli Modified scale in use in other countries. We have assembled a new SA/MCS-intensity data set from the DBMI04 intensity database and the ITACA accelerometric data bank. The SA peak values are calculated in two ways-using the maximum among the two horizontal components, and using the geometrical mean among the two horizontal components. The regression analysis has been performed separately for the two kinds of data sets and for the three target periods. Since both peak ground parameters and intensities suffer of appreciable uncertainties, we have used the orthogonal distance regression technique. Also, tests designed to assess the robustness of the estimated coefficients have shown that single-line parametrizations for the regressions are sufficient to model the data within the model uncertainties. For the maximum horizontal component, SAxx(hm), the new relations are I(MCS) = (1.24 +/- 0.33) + (2.47 +/- 0.18) log SA0.3s(hm), sigma = 0.53, I(MCS) = (3.12 +/- 0.16) + (2.05 +/- 0.11) log SA1.0s(hm), sigma = 0.36, I(MCS) = (4.31 +/- 0.10) + (2.00 +/- 0.10) log SA2.0s(hm), sigma = 0.29. For the geometrical mean SA, SAxx(gm), the new relations are I(MCS) = (1.40 +/- 0.31) + (2.46 +/- 0.18) log SA0.3s(gm), sigma = 0.53, I(MCS) = (3.25 +/- 0.16) + (2.08 +/- 0.12) log SA1.0s(gm), sigma = 0.38, I(MCS) = (4.46 +/- 0.10) + (2.01 +/- 0.10) log SA2.0s(gm), sigma = 0.30. Adoption of the geometric mean of the horizontal components, rather than their maximum value, results in a minor shift towards larger values of intensity for the same level of ground motion; this difference, however, is contained within the regression standard errors of the former. Comparisons carried out in various manners for earthquakes where both kinds of data (macroseismic and instrumental data) are available have shown the general effectiveness of the relations.
    Description: swissnuclear
    Description: Published
    Description: 1415-1430
    Description: 4.1. Metodologie sismologiche per l'ingegneria sismica
    Description: JCR Journal
    Description: reserved
    Keywords: Earthquake ground motions ; Europe ; Seismicity and tectonics ; RESPONSE SPECTRA ; 04. Solid Earth::04.06. Seismology::04.06.04. Ground motion
    Repository Name: Istituto Nazionale di Geofisica e Vulcanologia (INGV)
    Type: article
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    PAPER (OA)
  • 7
    facet.materialart.
    Unknown
    Frequency variation in site response as observed from strong motion data of the L’Aquila (2009) seismic sequence (2012)
    Springer
    Details
    Publication Date: 2017-04-04
    Description: Previous works based mainly on strong-motion recordings of large Japanese earthquakes showed that site amplification and soil fundamental frequency could vary over long and short time scales. These phenomena were attributed to non-linear soil behaviour: the starting fundamental frequency and amplification were both instantaneously decreasing and then recovering for a time varying from few seconds to several months. The recent April 6, 2009 earthquake (M W 6.3), occurred in the L’Aquila district (central Italy), gave us the possibility to test hypotheses on time variation of amplification function and soil fundamental frequency, thanks to the recordings provided by a pre-existing strong-motion array and by a large number of temporary stations. We investigated the intra- and inter-event soil frequency variations through different spectral analyses, including time-frequency spectral ratios and S-Transform (Stockwell et al. in IEEE Trans Signal Process 44:998–1001, 1996). Finally, analyses on noise recordings were performed, in order to study the soil behaviour in linear conditions. The results provided puzzling evidences. Concerning the long time scale, little variation was observed at the permanent stations of the Aterno Valley array. As for the short time-scale variation, the evidence was often contrasting, with some station showing a time-varying behavior, while others did not change their frequency with respect to the one evaluated from noise measurements. Even when a time-varying fundamental frequency was observed, it was difficult to attribute it to a classical, softening non-linear behaviour. Even for the strongest recorded shocks, with peak ground acceleration reaching 0.7 g, variations in frequency and amplitude seems not relevant from building design standpoint. The only exception seems to be the site named AQV, where the analyses evidence a fundamental frequency of the soil shifting from 3 Hz to about 1.5 Hz during the mainshock.
    Description: Published
    Description: 869-892
    Description: 4.1. Metodologie sismologiche per l'ingegneria sismica
    Description: JCR Journal
    Description: open
    Keywords: Strong motion ; Subsoil non-linearity ; 04. Solid Earth::04.06. Seismology::04.06.04. Ground motion
    Repository Name: Istituto Nazionale di Geofisica e Vulcanologia (INGV)
    Type: article
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    PAPER (OA)
  • 8
    facet.materialart.
    Unknown
    Microzonation of Potenza (Southern Italy) in terms of spectral intensity ratio using joint analysis of earthquakes and ambient noise. (2013)
    Springer
    Details
    Publication Date: 2017-04-04
    Description: A temporary seismic network composed of 11 stations was installed in the city of Potenza (Southern Italy) to record local and regional seismicity within the context of a national project funded by the Italian Department of Civil Protection (DPC). Some stations were moved after a certain time in order to increase the number of measurement points, leading to a total of 14 sites within the city by the end of the experiment. Recordings from 26 local earthquakes (Ml 2.2−3.8 ) were analyzed to compute the site responses at the 14 sites by applying both reference and non-reference site techniques. Furthermore, the Spectral Intensity (SI) for each local earthquake, as well as their ratios with respect to the values obtained at a reference site, were also calculated. In addition, a field survey of 233 single station noise measurements within the city was carried out to increase the information available at localities different from the 14 monitoring sites. By using the results of the correlation analysis between the horizontal-to-vertical spectral ratios computed from noise recordings (NHV) at the 14 selected sites and those derived by the single station noise measurements within the town as a proxy, the spectral intensity correction factors for site amplification obtained from earthquake analysis were extended to the entire city area. This procedure allowed us to provide a microzonation map of the urban area that can be directly used when calculating risk scenarios for civil defence purposes. The amplification factors estimated following this approach show values increasing along the main valley toward east where the detrital and alluvial complexes reach their maximum thickness.
    Description: Published
    Description: 493-516
    Description: 4.1. Metodologie sismologiche per l'ingegneria sismica
    Description: JCR Journal
    Description: restricted
    Keywords: site effect ; seismic noise ; spectral intensity ; correlation ; 04. Solid Earth::04.06. Seismology::04.06.04. Ground motion
    Repository Name: Istituto Nazionale di Geofisica e Vulcanologia (INGV)
    Type: article
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    PAPER (OA)
  • 9
    facet.materialart.
    Unknown
    Separation of source and site effects by Generalized Inversion Technique using the aftershock recordings of the 2009 L'Aquila earthquake (2012)
    Springer
    Details
    Publication Date: 2017-04-04
    Description: We exploit S-wave spectral amplitudes from 112 aftershocks (3.0 ≤ ML ≤ 5.3) of the L’Aquila 2009 seismic sequence recorded at 23 temporary stations in the epicentral area to estimate the source parameters of these events, the seismic attenuation characteristics and the site amplification effects at the recording sites. The spectral attenuation curves exhibit a very fast decay in the first few kilometers that could be attributed to the large attenuation of waves traveling trough the highly heterogeneous and fractured crust in the fault zone of the L’Aquila mainshock. The S-waves total attenuation in the first 30 km can be parameterized by a quality factor QS(f) = 23f^0.58 obtained by fixing the geometrical spreading to 1/R. The source spectra can be satisfactorily modeled using the omega-square model that provides stress drops between 0.3 and 60 MPa with a mean value of 3.3±2.8 MPa. The site responses show a large variability over the study area and significant amplification peaks are visible in the frequency range from 1 to more than 10 Hz. Finally, the vertical component of the motion is amplified at a number of sites where, as a consequence, the horizontal-to-vertical spectral ratios (HVSR) method fails in detecting the amplitude levels and in few cases the resonance frequencies.
    Description: Published
    Description: 717-739
    Description: 4.1. Metodologie sismologiche per l'ingegneria sismica
    Description: JCR Journal
    Description: reserved
    Keywords: Generalized Inversion Technique ; 2009 L'Aquila earthquake ; 04. Solid Earth::04.06. Seismology::04.06.99. General or miscellaneous ; 04. Solid Earth::04.06. Seismology::04.06.04. Ground motion
    Repository Name: Istituto Nazionale di Geofisica e Vulcanologia (INGV)
    Type: article
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    PAPER (OA)
  • 10
    facet.materialart.
    Unknown
    Proposal for a soil classification based on parameters alternative or complementary to Vs,30 (2012)
    Springer
    Details
    Publication Date: 2017-04-04
    Description: The selection of specific elastic response spectra according to soil categories is the easiest way to account for site effects in engineering projects and general-purpose hazard maps. Most of the international seismic codes make use of the average shear wave velocity of the upper 30 m (Vs,30) to discriminate soil categories, although some doubts arose about the capability of Vs,30 to predict actual soil amplification. In this work we propose two soil classifications in which the soil fundamental frequency (f0) becomes either an alternative or a complement to Vs,30. The performance of the derived categorizations is achieved through the estimation of the standard deviation associated to ground motion prediction equations of acceleration response spectra, considering recordings extracted from the Italian strong motion data base. The results indicate that there is a significant reduction of the standard deviation when the classification is based on the couple of variables Vs,30–f0, although a classification based of the single f0 also leads to satisfactory results, comparable with those obtained assuming a classification scheme based on Vs,30.
    Description: Published
    Description: 1877-1898
    Description: 4.1. Metodologie sismologiche per l'ingegneria sismica
    Description: JCR Journal
    Description: reserved
    Keywords: site effects ; soil classification ; 04. Solid Earth::04.06. Seismology::04.06.04. Ground motion
    Repository Name: Istituto Nazionale di Geofisica e Vulcanologia (INGV)
    Type: article
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    PAPER (OA)
Close ⊗
This website uses cookies and the analysis tool Matomo. More information can be found here...