Publication Date:
2013-04-25
Description:
Key Points The adaptor molecule SAP is required for T-cell receptor-induced iNKT cell killing of T- and B-cell targets. SAP-deficient iNKT cells adhere poorly to T-cell lymphoid targets and exhibit reduced polarization of lytic machinery to the immunologic synapse.
Print ISSN:
0006-4971
Electronic ISSN:
1528-0020
Topics:
Biology
,
Medicine
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