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  • Articles  (198)
  • 2010-2014  (94)
  • 1990-1994  (81)
  • 1965-1969  (23)
  • Medicine  (198)
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  • Articles  (198)
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  • 1
    ISSN: 1546-1718
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Medicine
    Notes: [Auszug] Autosomal dominant retinitis pigmentosa (adRP) is known to result from mutations in two different retinal genes—rhodopsin and peripherin—while a third locus has been implicated by linkage data. However, families have been reported in which all three known loci have been excluded. We ...
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  • 2
    Electronic Resource
    Electronic Resource
    [s.l.] : Nature Publishing Group
    Nature 222 (1969), S. 1250-1253 
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] Counting and sizing of the chromocentres in mouse fibroblast-like cells is feasible. It has shown that, in spite of the great variations of chromocentres in a population of such cells, there are certain ...
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  • 3
    Electronic Resource
    Electronic Resource
    [s.l.] : Nature Publishing Group
    Nature 206 (1965), S. 1215-1219 
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] IN two recent papers1,2 Dr. G. G. Pinter and Dr. J. L. Shohet have discussed a model of the renal medulla. The central feature of this model is that even though the counter current multiplier action of Henle's loop is restricted to the thick segment of the ascending limb, that is to the outer zone ...
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  • 4
    Electronic Resource
    Electronic Resource
    [s.l.] : Nature Publishing Group
    Nature 206 (1965), S. 924-925 
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] The structures of these two phases, the erystallographie constants of which are given in Table 1, have now been determined and refined by three-dimensional Fourier and least-squares techniques by us. Both are layer structures containing sheets of irregular molybdenum-oxygen octa-hedra. The sheets, ...
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  • 5
    Electronic Resource
    Electronic Resource
    [s.l.] : Nature Publishing Group
    Nature 222 (1969), S. 790-791 
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] Fig. 1. In each graph the ordinate ybdyb is the ratio of receptors occupied by agonist in the presence of both rapidly and slowly dissociating antagonists to those occupied by the agonist in the presence of only the slow antagonist. X, Y and Z represent the proportion of receptors occupied (in the ...
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  • 6
    Electronic Resource
    Electronic Resource
    [s.l.] : Nature Publishing Group
    Nature 207 (1965), S. 850-851 
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] The rock containing the burrows resembles the coquinas described by Thompson1. It is cream-coloured granular limestone which in thin section is seen to consist of fragments of shell, with some foraminifera and a few quartz grains, cemented together by calcite. In outcrop the bedding is picked out ...
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  • 7
    Electronic Resource
    Electronic Resource
    Springer
    Bulletin of environmental contamination and toxicology 53 (1994), S. 486-492 
    ISSN: 1432-0800
    Source: Springer Online Journal Archives 1860-2000
    Topics: Energy, Environment Protection, Nuclear Power Engineering , Medicine
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  • 8
    Electronic Resource
    Electronic Resource
    Springer
    Bulletin of environmental contamination and toxicology 53 (1994), S. 479-485 
    ISSN: 1432-0800
    Source: Springer Online Journal Archives 1860-2000
    Topics: Energy, Environment Protection, Nuclear Power Engineering , Medicine
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  • 9
    Electronic Resource
    Electronic Resource
    Springer
    Archives of environmental contamination and toxicology 20 (1991), S. 73-80 
    ISSN: 1432-0703
    Source: Springer Online Journal Archives 1860-2000
    Topics: Energy, Environment Protection, Nuclear Power Engineering , Medicine
    Notes: Abstract The acute toxicity of a technical formulation of pentachlorophenol (PCP) and pure pentachlorophenol to three age classes ofDaphnia magna, and adultD. pulex andD. galeata mendotae was determined by static toxicity tests. The influence of a number of factors on toxicity of PCP was also examined. The 48-hr LC50 estimates for adult daphnids of the three species exposed to pure PCP were 1.78, 4.59 and 0.51 mg/L, respectively, while those for the technical formulation were 2.57, 3.66 and 0.33 mg/L, respectively. There was little difference in toxicity between the technical and pure PCP; however, toxicity of both forms of PCP was influenced by duration of exposure, age (and/or size) and species of test organism and pH of the test solution. Pentachlorophenol caused a toxic response over a very narrow range of concentrations, with the greatest response occurring immediately between 0 and 24 hr. Pure PCP was equally toxic to all age classes ofD. magna but susceptibility to technical PCP decreased with maturation.D. g. mendotae was ten times more sensitive thanD. pulex to PCP. Pure PCP was significantly more toxic toD. magna at pH 5.5 than 7.0 with mean 48-hr LC50 values of 0.082 and 1.78 mg PCP/L, respectively. At 12°C, the toxicity of both forms of PCP toD. g. mendotae andD. pulex did not differ significantly from that at 20°C; however, technical PCP was significantly more toxic toD. magna at 12°C for an exposure duration of 48 hr. There was no effect of test container size (100, 250, 600 and 1,000 mL) on the toxicity of PCP toD. magna at 20°C with the lower pH of 5.5, suggesting that adsorption to glassware was not a factor in availability of PCP to test organisms. Beaker size had no effect on the toxicity of PCP toD. pulex at 20°C with test solutions having a pH of 7.0-8.0.
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  • 10
    Electronic Resource
    Electronic Resource
    Springer
    Archives of environmental contamination and toxicology 25 (1993), S. 27-35 
    ISSN: 1432-0703
    Source: Springer Online Journal Archives 1860-2000
    Topics: Energy, Environment Protection, Nuclear Power Engineering , Medicine
    Notes: Abstract Bioassays using rapid-cycling plants allow measurement of multiple endpoints and assessment of impacts on both growth and reproduction. Selections of Brassica rapa develop rapidly in a broad range of soils and are very consistent in production of flower and seed. Their sensitivity to variation in growth conditions was investigated to define the variables that most affect performance. Yield differences between soils were substantial, indicating the need for careful selection and use of control treatments. The sensitivity to contaminants was investigated with applications of mercury (Hg) and zinc (Zn) to three soils. In a sand soil, bloom initiation was slowed by 〈10 mg Hg kg−1 soil and 〈50 mg Zn kg−1 soil. In contrast, lettuce emergence and earthworm survival were less sensitive to these metals in this soil. Survival of Daphnia magna and the Microtox® assay in soil extracts were more sensitive to Hg than bloom initiation, but less sensitive to Zn. A similar relationship among the bioassays was observed for two finer-textured soils, although for these, effects were usually apparent only at soil metal concentrations 〉200 mg kg−1. Enzyme assays were included for comparison, but were not sensitive to Hg contamination. Rapid-cycling B. rapa selections are suitable for routine bioassays, and are representative of several widely distributed and utilized species.
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