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  • 2010-2014  (1)
  • 1995-1999  (1)
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    Translational Approaches for Studying Neurodevelopmental Disorders Utilizing in Vivo Proton (+H) Magnetic Resonance Spectroscopic Imaging in Rats (2014)
    In:  CASI
    Details
    Publication Date: 2019-07-19
    Description: Intrauterine complications have been implicated in the etiology of neuripsychiatric disorders including schizophrenia, autism and ADHD. This presentation will describe new translational studies derived from in vivo magnetic resonance imaging of developing and adult brain following perinatal asphyxia (PA). Our findings reveal significant effects of PA on neurometabolic profiles at one week of age, and significant relationships between early metabolites and later life phenotypes including behavior and brain morphometry
    Keywords: Behavioral Sciences
    Type: ARC-E-DAA-TN13021 , BIT''s Annual conference and EXPO of AnalytiX-2014; Apr 25, 2014 - Apr 28, 2014; Dalian, China; China
    Format: application/pdf
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    NASA TECHNICAL REPORTS
  • 2
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    Gravity-Loading During Pregnancy and Birth: Effects on Neonatal Outcome (1998)
    In:  Other Sources
    Details
    Publication Date: 2019-07-18
    Description: In this presentation, I will describe the effects of increased gravity on mammalian development in rodents, from gestation throughout weaning. The work is based on studies of centrifugation-induced hypergravity-rearing, the fundamentals of which will be described. The key variables include: 1) comparison of first-time (primparous) and experienced (multiparous) rodent mothers; 2) prenatal adaptation to the centrifuge; and 3) application of a modest g-load (1.5-g). The reported findings emphasize pregnancy, labor and birth, maternal care and lactation in the dams, and suckling, growth, development, and weaning in the offspring. Pregnancy success and offspring growth and survival will be discussed.
    Keywords: Life Sciences (General)
    Format: text
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