ISSN:
0947-3440
Keywords:
Multistriatin
;
2,3-O-(3-Pentylidene)-D-glyceraldehyde
;
Wittig Olefination, cis-selective
;
Michael reaction, diastereoselective
;
Hydrogenation, diastereoselective
;
Chemistry
;
Organic Chemistry
Source:
Wiley InterScience Backfile Collection 1832-2000
Topics:
Chemistry and Pharmacology
Notes:
Starting from 2,3-O-(3-pentylidene)-D-glyceraldehyde (3), we prepared the bicyclic pheromone (1S,2S,4R,5R)-(-)-β-multistriatin (1) on a gram scale. Key steps of the synthesis are a cis-selective Wittig olefination followed by diastereo-selective Michael addition and hydrogenation.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1002/jlac.1995199506143
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