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  • *Extraterrestrial Environment  (1)
  • Abrotanella  (1)
  • Base Sequence  (1)
  • American Association for the Advancement of Science (AAAS)  (2)
  • Springer  (1)
  • 2010-2014  (1)
  • 1995-1999  (2)
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  • American Association for the Advancement of Science (AAAS)  (2)
  • Springer  (1)
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  • 1
    Electronic Resource
    Electronic Resource
    Springer
    Plant systematics and evolution 216 (1999), S. 231-241 
    ISSN: 1615-6110
    Keywords: Asteraceae ; Senecioneae ; Blennospermatinae ; Abrotanella ; Blennosperma ; Crocidium ; Ischnea ; Flavonoids ; phytogeography ; disjunct ; pacific
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Abstract The flavonoid profiles of seven species ofAbrotanella and one species ofIschnea have been shown to be based upon kaempferol 3- and quercetin 3-O-glycosides and a delphinidin glycoside. Glucosides, glucuronides, arabinosides, diglucosides, and rutinosides of the flavonols were identified. The profile ofIschnea consisted solely of quercetin 3-O-glucoside and 3-O-arabinoside whereas the profiles of theAbrotanella species were more varied. Although infraspecific variation was not investigated in this study, the flavonoid chemistry of the two genera is in accordance with the flavonoid variation described for other members ofSenecioneae which are primarily flavonol producers. Based on the known phylogeny and biogeography, the flavonoid distribution from the perspective of long-distance dispersals across the Pacific is discussed. Such events should lead to genetic bottle-neck situations and depauperate flavonoid profiles. A summary of current flavonoid knowledge in theSenecioneae is supplied.
    Type of Medium: Electronic Resource
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  • 2
    Publication Date: 1996-04-26
    Description: Nerve growth factor (NGF), brain-derived neurotrophic factor (BDNF), and neurotrophin-3 (NT-3) selectively bind to distinct members of the Trk family of tyrosine kinase receptors, but all three bind with similar affinities to the neurotrophin receptor p75 (p75NTR). The biological significance of neurotrophin binding to p75NTR in cells that also express Trk receptors has been difficult to ascertain. In the absence of TrkA, NGF binding to p75NGR activated the transcription factor nuclear factor kappa B (NF-kappa B) in rat Schwann cells. This activation was not observed in Schwann cells isolated from mice that lacked p75NTR. The effect was selective for NGF; NF-kappa B was not activated by BDNF or NT-3.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Carter, B D -- Kaltschmidt, C -- Kaltschmidt, B -- Offenhauser, N -- Bohm-Matthaei, R -- Baeuerle, P A -- Barde, Y A -- New York, N.Y. -- Science. 1996 Apr 26;272(5261):542-5.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Department of Neurobiochemistry, Max-Planck Institute for Psychiatry, Martinsried, Germany.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/8614802" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Base Sequence ; Brain-Derived Neurotrophic Factor ; Cell Nucleus/metabolism ; Cells, Cultured ; DNA/metabolism ; L Cells (Cell Line) ; Mice ; Molecular Sequence Data ; NF-kappa B/*metabolism ; Nerve Growth Factors/*metabolism/pharmacology ; Nerve Tissue Proteins/metabolism/pharmacology ; Neurotrophin 3 ; Proto-Oncogene Proteins/metabolism ; Rats ; Receptor Protein-Tyrosine Kinases/metabolism ; Receptor, Nerve Growth Factor ; Receptor, trkA ; Receptors, Nerve Growth Factor/*metabolism ; Schwann Cells/*metabolism ; Signal Transduction/*physiology
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 3
    Publication Date: 2013-12-11
    Description: The Radiation Assessment Detector (RAD) on the Mars Science Laboratory's Curiosity rover began making detailed measurements of the cosmic ray and energetic particle radiation environment on the surface of Mars on 7 August 2012. We report and discuss measurements of the absorbed dose and dose equivalent from galactic cosmic rays and solar energetic particles on the martian surface for ~300 days of observations during the current solar maximum. These measurements provide insight into the radiation hazards associated with a human mission to the surface of Mars and provide an anchor point with which to model the subsurface radiation environment, with implications for microbial survival times of any possible extant or past life, as well as for the preservation of potential organic biosignatures of the ancient martian environment.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Hassler, Donald M -- Zeitlin, Cary -- Wimmer-Schweingruber, Robert F -- Ehresmann, Bent -- Rafkin, Scot -- Eigenbrode, Jennifer L -- Brinza, David E -- Weigle, Gerald -- Bottcher, Stephan -- Bohm, Eckart -- Burmeister, Soenke -- Guo, Jingnan -- Kohler, Jan -- Martin, Cesar -- Reitz, Guenther -- Cucinotta, Francis A -- Kim, Myung-Hee -- Grinspoon, David -- Bullock, Mark A -- Posner, Arik -- Gomez-Elvira, Javier -- Vasavada, Ashwin -- Grotzinger, John P -- MSL Science Team -- New York, N.Y. -- Science. 2014 Jan 24;343(6169):1244797. doi: 10.1126/science.1244797. Epub 2013 Dec 9.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Southwest Research Institute, Boulder, CO 80302, USA.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/24324275" target="_blank"〉PubMed〈/a〉
    Keywords: *Cosmic Radiation ; Deinococcus/physiology/radiation effects ; *Exobiology ; *Extraterrestrial Environment ; Humans ; *Mars ; Organic Chemicals/analysis ; Radiation Dosage ; Space Flight ; Surface Properties/radiation effects
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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