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  • Wiley  (29)
  • American Association for the Advancement of Science (AAAS)  (5)
  • 2010-2014  (16)
  • 2000-2004  (18)
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  • 1
    Publication Date: 2004-01-01
    Print ISSN: 0361-5995
    Electronic ISSN: 1435-0661
    Topics: Geosciences , Agriculture, Forestry, Horticulture, Fishery, Domestic Science, Nutrition
    Published by Wiley
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  • 2
    Publication Date: 2002-01-01
    Print ISSN: 0361-5995
    Electronic ISSN: 1435-0661
    Topics: Geosciences , Agriculture, Forestry, Horticulture, Fishery, Domestic Science, Nutrition
    Published by Wiley
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  • 3
    Publication Date: 2001-09-01
    Print ISSN: 0361-5995
    Electronic ISSN: 1435-0661
    Topics: Geosciences , Agriculture, Forestry, Horticulture, Fishery, Domestic Science, Nutrition
    Published by Wiley
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  • 4
    Publication Date: 2004-03-01
    Print ISSN: 0361-5995
    Electronic ISSN: 1435-0661
    Topics: Geosciences , Agriculture, Forestry, Horticulture, Fishery, Domestic Science, Nutrition
    Published by Wiley
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  • 5
    Publication Date: 2012-02-18
    Description: The effect of the overlying water velocity on ammonium (NH 4 + ) uptake by benthic biofilms was studied in a recirculating laboratory flume (260 cm long, 29 cm wide), packed with 5 cm of silica sand arranged into bedforms. NH 4 + uptake was determined as the reduction in NH 4 + concentration in the water at average overlying water velocities of 0.8, 2, 4 and 8 cm s -1 . NH 4 + uptake was relatively constant under laminar flow conditions but increased when the flow regime became turbulent (〉4 cm s -1 ). This pattern was observed for two biofilms differing in their total biomass and in the abundance of the ammonia-oxidizing bacteria, thus indicating that NH 4 + uptake was strongly controlled by mass transfer processes. The near stoichiometric relationship between the rates of NH 4 + uptake and nitrate (NO 3 - ) accumulation suggests that aerobic nitrification was the main route for NH 4 + uptake. Microelectrode measurements showed a sharp decline of oxygen concentrations and pH values within the biofilms, thus supporting strong nitrification activity within the surficial section of the benthic biofilms. The results of this study highlight the key role of hydrodynamic conditions in regulating NH 4 + uptake in the transition from laminar to turbulent flow conditions. Copyright © 2012 John Wiley & Sons, Ltd.
    Print ISSN: 0885-6087
    Electronic ISSN: 1099-1085
    Topics: Architecture, Civil Engineering, Surveying , Geography
    Published by Wiley
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  • 6
    Publication Date: 2014-04-07
    Description: During the past several decades, corals worldwide have been affected by severe bleaching events leading to wide-spread coral mortality triggered by global warming. The symbiotic Red Sea coral Stylophora pistillata from the Gulf of Eilat is considered an opportunistic ‘r’ strategist. It can thrive in relatively unstable environments and is considered a stress-tolerant species. Here, we used a S. pistillata custom microarray to examine gene expression patterns and cellular pathways during short-term (13-day) heat stress. The results allowed us to identify a two-step reaction to heat stress, which intensified significantly as the temperature was raised to a 32°C threshold, beyond which, coping strategies failed at 34°C. We identified potential “early warning genes” and “severe heat-related genes”. Our findings suggest that during short-term heat stress, S. pistillata may divert cellular energy into mechanisms such as the ER-unfolded protein response (UPR) and ER-associated degradation (ERAD) at the expense of growth and biomineralization processes in an effort to survive and subsequently recover from the stress. We suggest a mechanistic theory for the heat stress responses that may explain the success of some species which can thrive under a wider range of temperatures relative to others. This article is protected by copyright. All rights reserved.
    Print ISSN: 1354-1013
    Electronic ISSN: 1365-2486
    Topics: Biology , Energy, Environment Protection, Nuclear Power Engineering , Geography
    Published by Wiley
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  • 7
    Publication Date: 2002-07-06
    Description: Recent advances in the realization of individual molecular-scale electronic devices emphasize the need for novel tools and concepts capable of assembling such devices into large-scale functional circuits. We demonstrated sequence-specific molecular lithography on substrate DNA molecules by harnessing homologous recombination by RecA protein. In a sequence-specific manner, we patterned the coating of DNA with metal, localized labeled molecular objects and grew metal islands on specific sites along the DNA substrate, and generated molecularly accurate stable DNA junctions for patterning the DNA substrate connectivity. In our molecular lithography, the information encoded in the DNA molecules replaces the masks used in conventional microelectronics, and the RecA protein serves as the resist. The molecular lithography works with high resolution over a broad range of length scales from nanometers to many micrometers.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Keren, Kinneret -- Krueger, Michael -- Gilad, Rachel -- Ben-Yoseph, Gdalyahu -- Sivan, Uri -- Braun, Erez -- New York, N.Y. -- Science. 2002 Jul 5;297(5578):72-5.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Department of Physics, Solid State Institute, Technion-Israel Institute of Technology, Haifa 32000, Israel.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/12098693" target="_blank"〉PubMed〈/a〉
    Keywords: Antibodies ; Biopolymers ; Biotin ; DNA/chemistry/genetics/*metabolism ; DNA, Single-Stranded/*metabolism ; Electric Conductivity ; *Electronics ; Glutaral ; Gold ; Microscopy, Atomic Force ; Microscopy, Electron, Scanning ; *Nanotechnology ; Nucleic Acid Hybridization ; Rec A Recombinases/chemistry/immunology/*metabolism ; Recombination, Genetic ; Silver ; Streptavidin ; Templates, Genetic
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 8
    Publication Date: 2003-11-25
    Description: The combination of their electronic properties and dimensions makes carbon nanotubes ideal building blocks for molecular electronics. However, the advancement of carbon nanotube-based electronics requires assembly strategies that allow their precise localization and interconnection. Using a scheme based on recognition between molecular building blocks, we report the realization of a self-assembled carbon nanotube field-effect transistor operating at room temperature. A DNA scaffold molecule provides the address for precise localization of a semiconducting single-wall carbon nanotube as well as the template for the extended metallic wires contacting it.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Keren, Kinneret -- Berman, Rotem S -- Buchstab, Evgeny -- Sivan, Uri -- Braun, Erez -- New York, N.Y. -- Science. 2003 Nov 21;302(5649):1380-2.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Department of Physics, Technion-Israel Institute of Technology, Haifa 32000, Israel.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/14631035" target="_blank"〉PubMed〈/a〉
    Keywords: Bacteriophage lambda ; Biotin/chemistry ; *DNA/chemistry ; DNA, Single-Stranded/chemistry ; DNA, Viral/chemistry ; Gold ; Microscopy, Atomic Force ; Microscopy, Electron, Scanning ; *Nanotechnology ; *Nanotubes, Carbon ; Rec A Recombinases/metabolism ; Recombination, Genetic ; Streptavidin/chemistry ; *Transistors, Electronic
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 9
    Publication Date: 2013-03-09
    Description: Bactericidal antibiotics kill by modulating their respective targets. This traditional view has been challenged by studies that propose an alternative, unified mechanism of killing, whereby toxic reactive oxygen species (ROS) are produced in the presence of antibiotics. We found no correlation between an individual cell's probability of survival in the presence of antibiotic and its level of ROS. An ROS quencher, thiourea, protected cells from antibiotics present at low concentrations, but the effect was observed under anaerobic conditions as well. There was essentially no difference in survival of bacteria treated with various antibiotics under aerobic or anaerobic conditions. This suggests that ROS do not play a role in killing of bacterial pathogens by antibiotics.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Keren, Iris -- Wu, Yanxia -- Inocencio, Julio -- Mulcahy, Lawrence R -- Lewis, Kim -- T-R01AI085585-01/AI/NIAID NIH HHS/ -- New York, N.Y. -- Science. 2013 Mar 8;339(6124):1213-6. doi: 10.1126/science.1232688.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Antimicrobial Discovery Center, Department of Biology, Northeastern University, Boston, MA 021156, USA.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/23471410" target="_blank"〉PubMed〈/a〉
    Keywords: Anaerobiosis ; Anti-Bacterial Agents/antagonists & inhibitors/*pharmacology ; *Drug Resistance, Bacterial ; Escherichia coli/*drug effects/metabolism ; Fluoroquinolones/antagonists & inhibitors/*pharmacology ; Norfloxacin/antagonists & inhibitors/*pharmacology ; Oxidative Stress ; Reactive Oxygen Species/*metabolism ; Thiourea/pharmacology
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 10
    Publication Date: 2014-08-12
    Description: Chromatin modifications are crucial for development, yet little is known about their dynamics during differentiation. Hematopoiesis provides a well-defined model to study chromatin state dynamics; however, technical limitations impede profiling of homogeneous differentiation intermediates. We developed a high-sensitivity indexing-first chromatin immunoprecipitation approach to profile the dynamics of four chromatin modifications across 16 stages of hematopoietic differentiation. We identify 48,415 enhancer regions and characterize their dynamics. We find that lineage commitment involves de novo establishment of 17,035 lineage-specific enhancers. These enhancer repertoire expansions foreshadow transcriptional programs in differentiated cells. Combining our enhancer catalog with gene expression profiles, we elucidate the transcription factor network controlling chromatin dynamics and lineage specification in hematopoiesis. Together, our results provide a comprehensive model of chromatin dynamics during development.〈br /〉〈br /〉〈a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4412442/" target="_blank"〉〈img src="https://static.pubmed.gov/portal/portal3rc.fcgi/4089621/img/3977009" border="0"〉〈/a〉   〈a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4412442/" target="_blank"〉This paper as free author manuscript - peer-reviewed and accepted for publication〈/a〉〈br /〉〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Lara-Astiaso, David -- Weiner, Assaf -- Lorenzo-Vivas, Erika -- Zaretsky, Irina -- Jaitin, Diego Adhemar -- David, Eyal -- Keren-Shaul, Hadas -- Mildner, Alexander -- Winter, Deborah -- Jung, Steffen -- Friedman, Nir -- Amit, Ido -- 1P50HG006193/HG/NHGRI NIH HHS/ -- P50 HG006193/HG/NHGRI NIH HHS/ -- New York, N.Y. -- Science. 2014 Aug 22;345(6199):943-9. doi: 10.1126/science.1256271. Epub 2014 Aug 7.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Department of Immunology, Weizmann Institute of Science, Rehovot, Israel. ; Institute of Life Sciences, The Hebrew University, Jerusalem, Israel. School of Computer Science and Engineering, The Hebrew University, Jerusalem, Israel. ; Institute of Life Sciences, The Hebrew University, Jerusalem, Israel. School of Computer Science and Engineering, The Hebrew University, Jerusalem, Israel. nir@cs.huji.ac.il ido.amit@weizmann.ac.il. ; Department of Immunology, Weizmann Institute of Science, Rehovot, Israel. nir@cs.huji.ac.il ido.amit@weizmann.ac.il.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/25103404" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Cell Lineage/genetics ; Chromatin/*metabolism ; Chromatin Immunoprecipitation/methods ; *Enhancer Elements, Genetic ; Female ; Gene Expression Profiling ; *Gene Expression Regulation ; Hematopoiesis/*genetics ; Hematopoietic Stem Cells/cytology/*metabolism ; Histones/chemistry/metabolism ; Mice ; Transcription Factors/*metabolism
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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