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  • 2010-2014  (137)
  • 2000-2004  (78)
  • 1955-1959  (7)
  • 1920-1924  (1)
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  • 1
    Monograph available for loan
    Monograph available for loan
    Schlüsselkompetenzen : Literatur recherchieren in Bibliotheken und Internet (2010)
    Stuttgart [u.a.] : Metzler
    Details Availability
    Call number: PIK F 440-12-0256
    Description / Table of Contents: Contents: Einleitung ; 1 Informationsbedarf feststellen - Recherche vorbereiten ; 2 Recherche durchführen ; 3 Literatur beschaffen ; 4 Informationen bewerten ; 5 Informationen weiterverarbeiten ; 6 Beispielrecherchen ; 7 Epilog: Was in der Praxis dennoch schiefgeht ; 8. Materialien
    Type of Medium: Monograph available for loan
    Pages: VI, 145 S. : Ill., graph. Darst.
    ISBN: 3476022668 , 978-3-476-02266-0
    Location: A 18 - must be ordered
    Branch Library: PIK Library
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  • 2
    Monograph available for loan
    Monograph available for loan
    Grundzüge der Lithologie : Lehre von den Sedimentgesteinen (1958)
    Berlin : Akad.-Verl.
    Details Availability
    Call number: G 5471 ; G 6451
    Type of Medium: Monograph available for loan
    Pages: XIII, 806 S. : graph. Darst., Kt.
    Uniform Title: Osnovy litologii
    Language: German
    Location: Upper compact magazine
    Location: Upper compact magazine
    Branch Library: GFZ Library
    Branch Library: GFZ Library
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  • 3
    Unknown
    Schlüsselkompetenzen: Literatur recherchieren in Bibliotheken und Internet (2014)
    Stuttgart [u.a.] : Metzler
    Details Availability
    Call number: M 17.90482
    Keywords: Literaturrecherche ; Bibliothek ; Internet
    Description / Table of Contents: Gewusst wie! Von der Auswahl der Datenbanken und Suchmaschinen über den Einsatz der geeigneten Suchbegriffe und die Auswertung der Ergebnisse, bis hin zum korrekten Zitieren und dem Erstellen eigener Literaturlisten, der Ratgeber demonstriert Schritt für Schritt, wie man die passende Literatur findet und verarbeitet. Berücksichtigt werden neben gedruckten Quellen, wie Büchern, Zeitschriften und Zeitungen, auch frei verfügbare oder lizenzpflichtige Internet-Ressourcen. Für die 2. Auflage wurde der Band umfassend überarbeitet, aktualisiert und um Kapitel zur Nutzung von Zitationsdatenbanken, Discovery Services und den Umgang mit Open-Access-Publikationen erweitert. (Verlag)
    Description / Table of Contents: Einführung in die Literaturrecherche und -beschaffung während des Studiums mithilfe von Bibliothekskatalogen, Datenbanken und Internetsuchmaschinen. (LK/W: Thorn)
    Pages: VI, 161 S. , Ill., graph. Darst. , 23 cm
    Edition: 2., aktualisierte und erw. Aufl.
    ISBN: 9783476025203 (kart.)
    URL: http://www.vlb.de/GetBlob.aspx?strDisposition=a&strIsbn=9783476025203
    URL: http://cover.ekz.de/9783476025203.jpg
    URL: 04-Q-GBV
    URL: Inhaltstext
    URL: Inhaltsverzeichnis
    Parallel Title: 1. Aufl. u.d.T.: Franke, Fabian: Schlüsselkompetenzen
    Language: German
    Branch Library: GFZ Library
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  • 4
    Electronic Resource
    Electronic Resource
    High resolution temperature and density profiles during the energy quench of density limit disruptions in Rijnhuizen tokamak project (2002)
    [S.l.] : American Institute of Physics (AIP)
    Physics of Plasmas 9 (2002), S. 3402-3412 
    Details
    ISSN: 1089-7674
    Source: AIP Digital Archive
    Topics: Physics
    Notes: Measurements of the electron temperature, Te, and density, ne, during the energy quench of a major disruption showed that the onset of Te erosion in the neighborhood of the m/n=2/1 O point at the low field side (LFS) accelerates the well-known m/n=1/1 erosion of the core temperature. During this phase Te(r) is only partially flat in the region between the q=2 and the q=1 surfaces and ne(r) decreases in the core and increases inside the m/n=2/1 island. Immediately after the flattening of Te(r) a large peak in Te and to a lesser extent in ne has been observed. This peak is radially localized at the q=2 radius at the LFS, is very short lived and is poloidally asymmetric. Te profiles measured by the heterodyne radiometer and the Thomson scattering agree very well up to the time Te(r) flattens but afterwards can be a factor of two different. © 2002 American Institute of Physics.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1063/1.1489675
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  • 5
    Electronic Resource
    Electronic Resource
    Fabrication of large periodic arrays of AlGaAs microdisks by laser-interference lithography and selective etching (2002)
    Woodbury, NY : American Institute of Physics (AIP)
    Applied Physics Letters 81 (2002), S. 592-594 
    Details
    ISSN: 1077-3118
    Source: AIP Digital Archive
    Topics: Physics
    Notes: By laser-interference lithography, reactive-ion etching, and selective wet-chemical etching using a citric acid-based solution, we have fabricated large periodic arrays of AlGaAs microdisks with periods of 4 μm and disk diameters between 1.5 and 2 μm. The arrays are characterized by temperature-dependent photoluminescence spectroscopy. Taking into account the below-threshold absorption of the quantum wells inside the disks, we get disk quality factors close to the theoretical maximum value. We demonstrate that our technique allows one also to produce one-dimensionally or two-dimensionally coupled arrays of microdisks. © 2002 American Institute of Physics.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1063/1.1495082
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  • 6
    Electronic Resource
    Electronic Resource
    A common drug-responsive element mediates the upregulation of the Candida albicans ABC transporters CDR1 and CDR2, two genes involved in antifungal drug resistance (2002)
    Oxford, UK : Blackwell Science Ltd.
    Molecular microbiology 43 (2002), S. 0 
    Details
    ISSN: 1365-2958
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Biology , Medicine
    Notes: Upregulation of the ATP-binding cassette (ABC) transporter genes CDR1 and CDR2 (Candidadrug resistance 1 and 2) is a common mechanism observed in Candida albicans clinical isolates developing resistance to the class of azole antifungals. In this work, the regulatory elements of both genes were delimited using a reporter system in an azole-susceptible strain exposed to oestradiol, which allows transient induction of these genes. We found two regulatory elements in the CDR1 promoter: one responsible for basal expression (basal expression element; BEE) and the other required for oestradiol responsiveness (drug-responsive element I; DREI). In the CDR2 promoter, a single regulatory element responsible for oestradiol responsiveness (DREII) was detected. Both DREs shared a consensus of 21 bp with the sequence 5′-CGGA(A/T)ATCGGATATTTTTTTT-3′ having no equivalent to known eukaryotic regulatory sequence. Consistent with this finding, two other C. albicans genes identified by a search for the presence of DRE in the C. albicans genome sequence database were responsive to oestradiol. Finally, the regulatory elements found in CDR1 and CDR2 were also functional in an azole-resistant strain with constitutive high expression of both transporters. These results suggest that, although CDR1 and CDR2 upregulation can be obtained by transient drug-induced and constitutive upregulation, these two processes converge to the same regulatory elements and probably mobilize the same trans-acting factors.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1046/j.1365-2958.2002.02814.x
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  • 7
    Electronic Resource
    Electronic Resource
    The negative regulator Opi1 of phospholipid biosynthesis in yeast contacts the pleiotropic repressor Sin3 and the transcriptional activator Ino2 (2001)
    Oxford, UK : Blackwell Science Ltd
    Molecular microbiology 41 (2001), S. 0 
    Details
    ISSN: 1365-2958
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Biology , Medicine
    Notes: Structural genes of phospholipid biosynthesis in the yeast Saccharomyces cerevisiae are transcriptionally co-regulated by ICRE (inositol/choline-responsive element) promoter motifs. Gene activation by an ICRE is mediated by binding of the Ino2/Ino4 transcription factor, whereas repression in the presence of high concentrations of inositol and choline (IC) requires an intact Opi1 repressor. However, the mechanism of specific repression and the functional interplay among these regulators remained unclear from previous work. Using in vivo as well as in vitro interaction assays, we show binding of the pleiotropic repressor Sin3 to the pathway-specific regulator Opi1. The paired amphipathic helix 1 (PAH1) within Sin3 and OSID (Opi1–Sin3 interaction domain) in the N-terminus of Opi1 were mapped as contact sites. The regulatory significance of the Opi1–Sin3 interaction was shown by the obvious deregulation of an ICRE-dependent reporter gene in a sin3 mutant. Opi1 also interacts with a newly identified functional domain of the transcriptional activator Ino2 (RID, repressor interaction domain). These results define the molecular composition of the transcription complex mediating control of ICRE-dependent genes and allow a hypothesis on the flow of regulatory information in response to phospholipid precursors.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1046/j.1365-2958.2001.02495.x
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  • 8
    Electronic Resource
    Electronic Resource
    The nuclear actin-related protein Act3p/Arp4p of Saccharomyces cerevisiae is involved in transcription regulation of stress genes (2003)
    Oxford, UK : Blackwell Publishing Ltd.
    Molecular microbiology 50 (2003), S. 0 
    Details
    ISSN: 1365-2958
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Biology , Medicine
    Notes: A mutational analysis of the essential nuclear actin-related protein of Saccharomyces cerevisiae, Act3p/Arp4p, was performed. The five residues chosen for substitution were amino acids conserved between actin and Act3p/Arp4p, the tertiary structure of which most probably resembles that of actin. Two thermosensitive (ts) mutants, a single and a double point mutant, and one lethal double point mutant were obtained. Both ts mutants were formamide-sensitive which supports a structural relatedness of Act3p/Arp4p to actin; they were also hypersensitive against hydroxyurea and ultraviolet irradiation pointing to a possible role of Act3p/Arp4p in DNA replication and repair. Their ‘suppressor of Ty’ (SPT) phenotype, ob-served with another ts mutant of Act3p/Arp4p before, suggested involvement of Act3p/Arp4p in transcription regulation. Accordingly, genome-wide expression profiling revealed misregulated transcription in a ts mutant of a number of genes, among which increased expression of various stress-responsive genes (many of them requiring Msn2p/Msn4p for induction) was the most salient result. This provides an explanation for the mutant's enhanced resistance to severe thermal and oxidative stress. Thus, Act3p/Arp4p takes an important part in the repression of stress-induced genes under non-stress conditions.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1046/j.1365-2958.2003.03759.x
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  • 9
    Electronic Resource
    Electronic Resource
    TFIIB and subunits of the SAGA complex are involved in transcriptional activation of phospholipid biosynthetic genes by the regulatory protein Ino2 in the yeast Saccharomyces cerevisiae (2003)
    Oxford, UK : Blackwell Science Ltd
    Molecular microbiology 48 (2003), S. 0 
    Details
    ISSN: 1365-2958
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Biology , Medicine
    Notes: In the yeast Saccharomyces cerevisiae, genes involved in phospholipid biosynthesis are activated by ICRE (inositol/choline-responsive element) up-stream motifs and the corresponding heterodimeric binding factor, Ino2 + Ino4. Both Ino2 and Ino4 contain basic helix–loop–helix (bHLH) domains required for ICRE binding, whereas transcriptional activation is mediated exclusively by Ino2. In this work, we describe a molecular analysis of functional minimal domains responsible for specific DNA recognition and transcriptional activation (TAD1 and TAD2). We also define the importance of individual amino acids within the more important activation domain TAD1. Random mutagenesis at five amino acid positions showed the importance of acidic as well as hydrophobic residues within this minimal TAD. We also investigated the contribution of known general transcription factors and co-activators for Ino2-dependent gene activation. Although an ada5 single mutant and a gal11 paf1 double mutant were severely affected, a partial reduction in activation was found for gcn5 and srb2. Ino2 interacts physically with the basal transcription factor Sua7 (TFIIB of yeast). Interestingly, interaction is mediated by the HLH dimerization domain of Ino2 and by two non-overlapping domains within Sua7. Thus, Sua7 may compete with Ino4 for binding to the Ino2 activator, creating the possibility of positive and negative influence of Sua7 on ICRE-dependent gene expression.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1046/j.1365-2958.2003.03501.x
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  • 10
    Electronic Resource
    Electronic Resource
    Über die Bestimmung der Spurenelemente in der Agrikulturchemie (1956)
    Springer
    Microchimica acta 44 (1956), S. 393-400 
    Details
    ISSN: 1436-5073
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology
    Description / Table of Contents: Summary A method is described for determining the trace elements in soils, plants, feeds, and fertilizers. The trace elements are separated from the major constituents and concentrated by shaking with complex-forming compounds, after destroying the organic material, the concentrate obtained is dissolved in acid. These solutions are brought continuously on a disk of spectrum carbon and simultaneously spectrographed in sparks. The evaluation is made by comparison with solutions of known content in the usual manner.
    Abstract: Résumé Description d'une méthode de dosage des oligoéléments dans les sols, les plantes, la nourriture et les engrais. Les éléments sont séparés de la matière à analyser, concentrés par agitation avec des substances complexantes. Après destruction de la matière organique les concentrés obtenus sont dissouts dans un acide. Ces solutions sont amenées de façon continue sur un disque en carbone pur et analysées par spectrographie d'étincelles. La détermination se fait par comparaison avec des solutions étalons suivant la méthode classique.
    Notes: Zusammenfassung Es wird eine Methode zur Bestimmung der Spurenelemente in Böden, Pflanzen, Futter- und Düngemitteln beschrieben. Die Spurenelemente werden von den Hauptbestandteilen getrennt, durch Ausschüttelung mit komplexbildenden Verbindungen angereichert, nach Zerstörung der organischen Substanz die erhaltenen Konzentrate in Säure gelöst. Diese Lösungen werden auf einer Scheibe aus spektralreiner Kohle kontinuierlich aufgebracht und gleichzeitig im Funken spektrographiert. Die Auswertung erfolgt durch Vergleich mit Lösungen bekannten Gehaltes in üblicher Weise.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01216624
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