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  • Lunar and Planetary Science and Exploration  (7)
  • Organic Chemistry  (7)
  • 2010-2014  (7)
  • 2000-2004
  • 1980-1984  (6)
  • 1940-1944  (1)
  • 1930-1934
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  • 1
    ISSN: 0018-019X
    Keywords: Chemistry ; Organic Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Notes: An efficient and flexible method for the preparation of silyl nitronates is described (see 1-10). NMR. spectral investigations indicate a rapid 1,3-silyl migration process, with an activation energy of about 10 kcal mol-1. X-ray crystallographic studies on the silyl nitronates 3 and 8 show structures that lean towards an SN2 retention pathway at silicon.
    Additional Material: 5 Ill.
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  • 2
    Electronic Resource
    Electronic Resource
    New York, NY : Wiley-Blackwell
    Helvetica Chimica Acta 63 (1980), S. 728-732 
    ISSN: 0018-019X
    Keywords: Chemistry ; Organic Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Notes: Enhancement of Detection Sensitivity of Cyclosporin A by Derivatization with 2-NapthylselenylchlorideThe UV./HPLC. detection sensitivity of cyclosporine A 1, an immunosuppressive cyclic undecapeptide containing one D-aminoacid and seven N-methylated aminoacids, is enhanced by a factor of 3-4 (limit of detection 5 ng) by conversion of the characteristic side chain of amino-acid-1 to the β-naphthylseleno-substituted tetrahydrofuran derivative 4.
    Additional Material: 2 Ill.
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  • 3
    ISSN: 0018-019X
    Keywords: Chemistry ; Organic Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Notes: Preparation of 1,3-Diketones and of Nitro-diketones by (1:1)-Acylation of Lithium Enolates with Acyl ChloridesSlow addition of precooled solutions of lithium enolates in THF (Fig. 1) to solutions of equimolar amounts of acyl chlorides in the same solvent at temperatures between - 80 and - 100° furnishes 1, 3-diketones in acceptable to good yields (Tables 1-3). Even 3-nitropropionyl and 4-nitrobutyryl chloride can be employed for the (1:1)-acylation of enolates to give the synthetically useful 5- and 6-nitro-1, 3-diketones 13 and 25, respectively. The scope and the limitations of this method of preparing 1, 3-diketones are given and are compared with alternative methods.
    Additional Material: 1 Ill.
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  • 4
    ISSN: 0018-019X
    Keywords: Chemistry ; Organic Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Notes: Regioselective and flexible procedures are described for the preparation of a variety of protected vicinal nitroalcohols 1, 3 and 5 (see Scheme 5), as is an efficient method for their reduction to the corresponding vicinal aminoalcohols 2, 4 and 6.
    Additional Material: 1 Ill.
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  • 5
    ISSN: 0018-019X
    Keywords: Chemistry ; Organic Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Notes: Three methods are described by which diastereomerically enriched nitroaldols and their O-silylated derivatives can be prepared. threo-Nitroaldols prevail up to 10:1 over the erythro-isomers if doubly deprotonated nitroaldols 28 are quenched with acetic acid (THF/HMPT or DMPU, - 100°) (see Scheme 5 and Table 2). O-Trimethyl- or O-(t-butyl)dimethylsilylated (TBDMSi) erythro-nitroaldols can be obtained by protonation of the corresponding lithium nitronates (35, 39) in THF at low temperature (see Schemes 6 and 7). The erythro-O-TBDMSi-nitroaldol derivatives are also formed in the fluoride catalyzed addition of TBDMSi-nitronates (40-45) to aldehydes (see Schemes 8 and 9), In the latter reaction no 1,2-asymmetric induction is observed if a-branched silylnitronates or aldehydes are employed (see 48/49 and 50/51) - The stereochemical course of the reactions leading to erythro-O-TBDMSi-nitroaldols follows topological rules of broad applicability (see Scheme 10); possible mechnisms are discussed. - The configuration of diasteromerically 13C-NMR. Spectroscopy. - Some examples of the preparation of diastereimerically enriched 1,2-aminolcohols by reduction of the correspondence nitro compounds without loss of configurational purity are described (see Schemes 11 and 12).
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  • 6
    Electronic Resource
    Electronic Resource
    New York, NY : Wiley-Blackwell
    Journal für Praktische Chemie/Chemiker-Zeitung 156 (1940), S. 227-240 
    ISSN: 0021-8383
    Keywords: Chemistry ; Organic Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Notes: 1. Als Überspannung oder Hypertension der Moleküle wird ein Zustand bezeichnet, bei dem die Moleküle aus den Elementen unter starker Kontraktion, aber relativ geringer Energieabgabe entstanden sind. Die Valenzelektronen befinden sich daher in einem mehr oder weniger hochangeregten Zustand und suchen durch Eingehen neuer, komplexchemischer Reaktionen in einen stabileren Zustand überzugehen.
    Additional Material: 3 Ill.
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  • 7
    Electronic Resource
    Electronic Resource
    New York, NY : Wiley-Blackwell
    Journal für Praktische Chemie/Chemiker-Zeitung 325 (1983), S. 36-40 
    ISSN: 0021-8383
    Keywords: Chemistry ; Organic Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Notes: Studies on the Hydrolysis of Aromatic SulfochloridesThe hydrolysis of aromatic sulfochlorides can bei described by a second-order law. Due to the strength of the base the constants of velocity are between 10-6 (H2O) or 103 (OH-) 1 mol -1 s-1 respectively. The reaction of benzensulfochlorides proceeds according to an addition-elimination mechanism, whereas benzylic sulfochlorides, reacting with a strong base, proceed to an elimination-addition mechanism.
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  • 8
    Publication Date: 2019-07-19
    Description: Following successful science operations at Vesta, the Dawn spacecraft is headed for an encounter with Ceres in 2015. What have we learned at Vesta? And, what do we expect to learn by comparing Vesta and Ceres? We will address these questions from the standpoint of geochemistry. Dawn's Gamma Ray and Neutron Detector (GRaND) is sensitive to the elemental composition of surface materials to depths of a few decimeters [1]. Gamma rays and neutrons, produced by the steady bombardment of galactic cosmic rays and by the decay of naturally ]occurring radioisotopes (K, Th, U), provide a chemical fingerprint of the regolith. Analysis of planetary radiation emissions enables mapping of specific elements (such as Fe, Mg, Si, Cl, and H) and compositional parameters (such as average atomic mass), which provide information about processes that shaped the planet1s surface and interior. Dawn has exceeded operational goals for GRaND at Vesta, accumulating an abundance of nadir-pointed data during five months in a 210 km, low altitude mapping orbit around Vesta (265-km mean radius). Chemical information from gamma ray and neutron measurements was used to test the connection between Vesta and the howardite, eucrite, and diogenite (HED) meteorites [2]. Additionally, GRaND searched for evolved, igneous lithologies [3], mantle and upper crustal materials exposed in large impact basins, mesosiderite compositions, and hydrogen in Vesta1s bulk regolith. Results of our analyses and their implications for thermal evolution and regolith-processes will be presented. The possibility of a subcrustal ocean [4, 5] and lack of cerean meteorites makes water-rich Ceres a compelling target of exploration [6]. If Ceres underwent aqueous differentiation, then crustal overturn or gas driven volcanism may have significantly modified its primitive surface; and products of aqueous alteration (e.g. [7]) would detectable by GRaND [1]. For example, the presence of Cl in salts, associated with liquid-water-processes, would have a profound effect on the thermal neutron leakage flux. GRaND is sensitive to H and H-layering, which may be in the form of endogenic water ice or hydrous minerals on Ceres. Ammonia ice (e.g., from recent cryovolcanism) would produce a distinctly different neutron signature than water ice [1]. Prospective results for GRaND at Ceres will be presented in the context of what we have learned about Vesta.
    Keywords: Lunar and Planetary Science and Exploration
    Type: JSC-CN-27224 , American Geophysical Union Fall Meeting; Dec 03, 2012 - Dec 07, 2012; San Francisco, CA; United States
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  • 9
    Publication Date: 2019-07-13
    Description: NASA's Dawn spacecraft entered orbit around asteroid (4) Vesta in July 2011 for a yearlong mapping orbit. The surface of Vesta as imaged by the Dawn Framing Camera (FC) revealed a surface that is unlike any asteroid we have visited so far with a spacecraft. Albedo and color variations on Vesta are the most diverse in the asteroid belt with a majority of these linked to distinct compositional units on the asteroid s surface. FC discovered dark material on Vesta. These low albedo surface features were first observed during Rotational Characterization 3 phase at a resolution of approx. 487 m/pixel. Here we explore the composition and possible meteoritical analogs for the dark material on Vesta.
    Keywords: Lunar and Planetary Science and Exploration
    Type: JSC-CN-26602 , 75th Annual Meeting of the Meteorical Society; Aug 12, 2012 - Aug 17, 2012; Cairns; Australia
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  • 10
    Publication Date: 2019-07-13
    Description: On 12-Dec-2011, the Dawn spacecraft commenced low altitude mapping of the giant asteroid, 4 Vesta (264-km mean radius). Dawn's roughly circular, polar, low altitude mapping orbit (LAMO) has a mean radius of 470 km, placing the spacecraft within about 210 km of Vesta's surface. At these altitudes, Dawn s Gamma Ray and Neutron Detector (GRaND) is sensitive to Vesta's elemental com-position (Fig. 1). GRaND will acquire data in LAMO for up to 16 weeks, which is sufficient to map the elemental composition of the entire surface of Vesta. The timing of LAMO enables us to report the first results of our geochemistry investigation at this conference. In this abstract, we present an overview of our initial observations, based on data acquired at high altitude and during the first weeks of LAMO. GRaND overview. A detailed description of the GRaND instrument, science objectives and prospective results is given in [1]. At low altitudes, GRaND is sensitive to gamma rays and neutrons produced by cosmogenic nuclear reactions and radioactive decay occurring within the top few decimeters of the surface and on a spatial scale of a few hundred kilometers. From these nuclear emissions, the abundance of several major- and minor-elements, such as Fe, Mg, Si, K, and Th can be determined. Assuming the howardite, eucrite, and diogenite (HED) meteorites are representative of Vesta s crustal composition [2], then GRaND will be able to map the mixing ratios of whole-rock HED end-members, enabling the determination of the relative proportions of basaltic eucrite, cumulate eucrite, and diogenite as well as the proportions of mafic and plagioclase minerals [1,3]. GRaND will also search for compositions not well-represented in the meteorite collection, such as evolved, K-rich lithologies [4], and outcrops of olivine from Vesta s mantle or igneous intrusions in major impact basins [5]. The search for a possible mesosiderite source region is described in [6]. GRaND will globally map the abundance of H, providing constraints on the delivery of H by solar wind and the infall of carbonaceous chondrite materials.
    Keywords: Lunar and Planetary Science and Exploration
    Type: JSC-CN-25720 , 43rd Lunar and Planetary Science Conference; Mar 19, 2012 - Mar 23, 2012; The Woodlands, TX; United States
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