Publication Date:
2014-03-21
Description:
Article The adipokine endotrophin promotes tumour inflammation and angiogenesis, but its effects on adipose tissue are unclear. Here, Sun et al. show that endotrophin promotes adipose tissue inflammation and fibrosis, and that injections of an anti-endotrophin antibody improve metabolic parameters of mice on a high-fat diet. Nature Communications doi: 10.1038/ncomms4485 Authors: Kai Sun, Jiyoung Park, Olga T. Gupta, William L. Holland, Pernille Auerbach, Ningyan Zhang, Roberta Goncalves Marangoni, Sarah M. Nicoloro, Michael P. Czech, John Varga, Thorkil Ploug, Zhiqiang An, Philipp E. Scherer
Electronic ISSN:
2041-1723
Topics:
Biology
,
Chemistry and Pharmacology
,
Natural Sciences in General
,
Physics
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