Publication Date:
2015-12-06
Description:
Article The mechanosensitive proteins talin and vinculin mediate the linkage between integrin-bound extracellular matrix and the actin cytoskeleton. Here the authors dissect distinct roles for two actin-binding sites within talin on adhesion complex assembly and maturation, which are regulated by vinculin binding to talin. Nature Communications doi: 10.1038/ncomms10038 Authors: Paul Atherton, Ben Stutchbury, De-Yao Wang, Devina Jethwa, Ricky Tsang, Eugenia Meiler-Rodriguez, Pengbo Wang, Neil Bate, Roy Zent, Igor L. Barsukov, Benjamin T. Goult, David R. Critchley, Christoph Ballestrem
Electronic ISSN:
2041-1723
Topics:
Biology
,
Chemistry and Pharmacology
,
Natural Sciences in General
,
Physics
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