Publication Date:
2022-05-26
Description:
© The Author(s), 2016. This is the author's version of the work. It is posted here under a nonexclusive, irrevocable, paid-up, worldwide license granted to WHOI. It is made available for personal use, not for redistribution. The definitive version was published in Marine Pollution Bulletin 115 (2017): 352-361, doi:10.1016/j.marpolbul.2016.12.012.
Description:
Pterygoplichthys is a genus of related suckermouth armoured catfish native to
South America that has invaded tropical and subtropical regions worldwide.
Physiological features, including an augmented resistance to organic xenobiotics,
may have aided their settlement in foreign habitats. The liver transcriptome of
Pterygoplichthys anisitsi was sequenced and used to characterize the diversity of
mRNAs potentially involved in the responses to natural and anthropogenic
chemicals. In total, 66,642 transcripts were assembled. Among the identified
defensome genes, cytochromes P450 (CYP) were the most abundant, followed by
nuclear receptors (NR), sulfotransferases (SULT) and ATP binding cassette
transporters (ABC). A novel expansion in the CYP2Y subfamily was identified, as
well as an independent expansion of the CYP2AAs. Two expansions were also
observed among SULT1. Thirty-nine transcripts were classified into twelve
subfamilies of NR, while 21 encoded ABC transporters. The diversity of defensome
transcripts sequenced herein could contribute to this species resistance to organic
xenobiotics.
Description:
This study was supported by a PEER grant from USAID (PGA-2000003446 and
PGA-2000004790) associated with NSF grant DEB-1120263. T.E.P, D.A.M, and
M.G.P.M receives independent fellowships from the Brazilian funding agency
CAPES.
Keywords:
RNA-Seq
;
P450
;
SULT
;
ABC transporters
;
Nuclear Receptors
Repository Name:
Woods Hole Open Access Server
Type:
Preprint
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