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  • Wiley  (2)
  • National Academy of Sciences  (1)
  • 2015-2019  (3)
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  • 1
    Publication Date: 2016-01-27
    Description: The discovery of cancer stem cells (CSCs), which are responsible for self-renewal and tumor growth in heterogeneous cancer tissues, has stimulated interests in developing new cancer therapies and early diagnosis. However, the markers currently used for isolation of CSCs are often not selective enough to enrich CSCs for the study...
    Print ISSN: 0027-8424
    Electronic ISSN: 1091-6490
    Topics: Biology , Medicine , Natural Sciences in General
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  • 2
    Publication Date: 2017-08-01
    Description: All sky camera observations carried out over Taiwan showed intense equatorial plasma bubbles (EPB) in 630.0 nm airglow images on consecutive nights of 13-16 March, 2015, but was absent in the following night of 17 March when St. Patrick's Day magnetic storm occurred. Rate of total electron content (TEC) index by using Global Positioning System (GPS) network data also confirmed the absence of irregularities on the night 17 March. The results however revealed strong irregularities over Indian sector on the same night. Flux tube integrated Rayleigh-Taylor instability growth rates computed using the prior (forecast) state of Thermosphere-Ionosphere Electrodynamics General Circulation Model output after assimilating the GPS-TEC measurements also agree with the observations, showing smaller values over Taiwan and larger values over India on the night of 17 March. The ionospheric response to the storm over Taiwan that resulted in the apparent inhibition of EPB is investigated in this study by using the data assimilation output. Results indicate that on the night of the magnetic storm, pre-reversal enhancement of zonal electric field over Taiwan was weaker when compared to that over India. Further analysis suggests that the absence of enhancement in the zonal electric field could be due to westward penetration electric field in response to rapid northward turning of interplanetary magnetic field that occurred during the dusk period over Taiwan.
    Print ISSN: 1539-4964
    Electronic ISSN: 1542-7390
    Topics: Geosciences , Physics
    Published by Wiley on behalf of American Geophysical Union (AGU).
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  • 3
    Publication Date: 2017-03-16
    Description: Flux tube integrated Rayleigh-Taylor instability growth rates computed using the results of ionosphere data assimilation are used for the first time to investigate global plasma bubble occurrence. The study is carried out by assimilating total electron content measurements using ground based global positioning system (GPS) receivers into thermosphere ionosphere electrodynamic general circulation model, and the growth rates are calculated using standalone model run without assimilation (control run) as well as using prior (or forecast) state output of the assimilation run. The growth rates are compared with rate of change of total electron content index (ROTI), estimated from global network of GPS receivers, as well as all sky airglow observations carried out over Taiwan on the nights of 16, and 17 March 2015. In contrast to the growth rates using the control run, results using data assimilation show remarkable agreement with the ROTI. Further, the all sky images reveal intense plasma bubbles over Taiwan on the night of 16 March, when the corresponding assimilated growth rate is also pronounced. Similarly, absence of plasma bubbles in the all sky images on the night of 17 March (St. Patrick's day storm) is supported by smaller growth rates predicted by the assimilation model. Significant improvements in the calculated growth rates could be achieved because of the accurate updating of zonal electric field in the data assimilation forecast. The results suggest that realistic estimate or prediction of plasma bubble occurrence could be feasible by taking advantage of the data assimilation approach adopted in this work.
    Print ISSN: 0148-0227
    Topics: Geosciences , Physics
    Published by Wiley on behalf of American Geophysical Union (AGU).
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