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  • Articles  (466)
  • American Geophysical Union  (236)
  • Molecular Diversity Preservation International  (181)
  • American Institute of Physics (AIP)
  • Cambridge University Press
  • 2015-2019  (466)
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  • Articles  (466)
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  • 1
    Publication Date: 2019-03-31
    Description: Soft, untethered microrobots composed of biocompatible materials for completing micromanipulation and drug delivery tasks in lab-on-a-chip and medical scenarios are currently being developed. Alginate holds significant potential in medical microrobotics due to its biocompatibility, biodegradability, and drug encapsulation capabilities. Here, we describe the synthesis of MANiACs—Magnetically Aligned Nanorods in Alginate Capsules—for use as untethered microrobotic surface tumblers, demonstrating magnetically guided lateral tumbling via rotating magnetic fields. MANiAC translation is demonstrated on tissue surfaces as well as inclined slopes. These alginate microrobots are capable of manipulating objects over millimeter-scale distances. Finally, we demonstrate payload release capabilities of MANiACs during translational tumbling motion.
    Electronic ISSN: 2072-666X
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
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  • 2
    Publication Date: 2017-04-04
    Description: Analysis of microgravity and surface displacement data collected at the summit of Kīlauea Volcano, Hawaii (USA), between December 2009 and November 2012 suggests a net mass accumulation at ~1.5 km depth beneath the northeast margin of Halema‘uma‘u Crater, within Kīlauea Caldera. Although residual gravity increases and decreases are accompanied by periods of uplift and subsidence of the surface, respectively, the volume change inferred from the modeling of interferometric synthetic aperture radar deformation data can account for only a small portion (as low as 8%) of the mass addition responsible for the gravity increase. We propose that since the opening of a new eruptive vent at the summit of Kīlauea in 2008, magma rising to the surface of the lava lake outgasses, becomes denser, and sinks to deeper levels, replacing less dense gas-rich magma stored in the Halema‘uma‘u magma reservoir. In fact, a relatively small density increase (〈200 kgm_3) of a portion of the reservoir can produce the positive residual gravity change measured during the period with the largest mass increase, between March 2011 and November 2012. Other mechanisms may also play a role in the gravity increase without producing significant uplift of the surface, including compressibility of magma, formation of olivine cumulates, and filling of void space by magma. The rate of gravity increase, higher than during previous decades, varies through time and seems to be directly correlated with the volcanic activity occurring at both the summit and the east rift zone of the volcano.
    Description: Published
    Description: 7288–7305
    Description: 2V. Dinamiche di unrest e scenari pre-eruttivi
    Description: JCR Journal
    Description: restricted
    Keywords: Mass accumulation ; Magma outgassing ; Gravity changes ; Ground deformation ; 04. Solid Earth::04.03. Geodesy::04.03.05. Gravity variations
    Repository Name: Istituto Nazionale di Geofisica e Vulcanologia (INGV)
    Type: article
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  • 3
    Publication Date: 2015-09-11
    Description: Pigment-protein complexes (PPCs) play a central role in facilitating excitation energy transfer (EET) from light-harvesting antenna complexes to reaction centres in photosynthetic systems; understanding molecular organisation in these biological networks is key to developing better artificial light-harvesting systems. In this article, we combine quantum-mechanical simulations and a network-based picture of transport to investigate how chromophore organization and protein environment in PPCs impacts on EET efficiency and robustness. In a prototypical PPC model, the Fenna-Matthews-Olson (FMO) complex, we consider the impact on EET efficiency of both disrupting the chromophore network and changing the influence of (local and global) environmental dephasing. Surprisingly, we find a large degree of resilience to changes in both chromophore network and protein environmental dephasing, the extent of which is greater than previously observed; for example, FMO maintains EET when 50% of the constituent chromophores are removed, or when environmental dephasing fluctuations vary over two orders-of-magnitude relative to the in vivo system. We also highlight the fact that the influence of local dephasing can be strongly dependent on the characteristics of the EET network and the initial excitation; for example, initial excitations resulting in rapid coherent decay are generally insensitive to the environment, whereas the incoherent population decay observed following excitation at weakly coupled chromophores demonstrates a more pronounced dependence on dephasing rate as a result of the greater possibility of local exciton trapping. Finally, we show that the FMO electronic Hamiltonian is not particularly optimised for EET; instead, it is just one of many possible chromophore organisations which demonstrate a good level of EET transport efficiency following excitation at different chromophores. Overall, these robustness and efficiency characteristics are attributed to the highly connected nature of the chromophore network and the presence of multiple EET pathways, features which might easily be built into artificial photosynthetic systems.
    Print ISSN: 0021-9606
    Electronic ISSN: 1089-7690
    Topics: Chemistry and Pharmacology , Physics
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  • 4
    Publication Date: 2016-05-06
    Description: The motion of cells and molecules through biological environments is often hindered by the presence of other cells and molecules. A common approach to modeling this kind of hindered transport is to examine the mean squared displacement (MSD) of a motile tracer particle in a lattice-based stochastic random walk in which some lattice sites are occupied by obstacles. Unfortunately, stochastic models can be computationally expensive to analyze because we must average over a large ensemble of identically prepared realizations to obtain meaningful results. To overcome this limitation we describe an exact method for analyzing a lattice-based model of the motion of an agent moving through a crowded environment. Using our approach we calculate the exact MSD of the motile agent. Our analysis confirms the existence of a transition period where, at first, the MSD does not follow a power law with time. However, after a sufficiently long period of time, the MSD increases in proportion to time. This latter phase corresponds to Fickian diffusion with a reduced diffusivity owing to the presence of the obstacles. Our main result is to provide a mathematically motivated, reproducible, and objective estimate of the amount of time required for the transport to become Fickian. Our new method to calculate this crossover time does not rely on stochastic simulations.
    Print ISSN: 0021-9606
    Electronic ISSN: 1089-7690
    Topics: Chemistry and Pharmacology , Physics
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  • 5
    Publication Date: 2015-05-06
    Description: Adiabat-shaping techniques were investigated in indirect drive inertial confinement fusion experiments on the National Ignition Facility as a means to improve implosion stability, while still maintaining a low adiabat in the fuel. Adiabat-shaping was accomplished in these indirect drive experiments by altering the ratio of the picket and trough energies in the laser pulse shape, thus driving a decaying first shock in the ablator. This decaying first shock is designed to place the ablation front on a high adiabat while keeping the fuel on a low adiabat. These experiments were conducted using the keyhole experimental platform for both three and four shock laser pulses. This platform enabled direct measurement of the shock velocities driven in the glow-discharge polymer capsule and in the liquid deuterium, the surrogate fuel for a DT ignition target. The measured shock velocities and radiation drive histories are compared to previous three and four shock laser pulses. This comparison indicates that in the case of adiabat shaping the ablation front initially drives a high shock velocity, and therefore, a high shock pressure and adiabat. The shock then decays as it travels through the ablator to pressures similar to the original low-adiabat pulses when it reaches the fuel. This approach takes advantage of initial high ablation velocity, which favors stability, and high-compression, which favors high stagnation pressures.
    Print ISSN: 1070-664X
    Electronic ISSN: 1089-7674
    Topics: Physics
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  • 6
    Publication Date: 2015-04-14
    Description: We present a miniaturized molecular beam epitaxy (miniMBE) system with an outer diameter of 206 mm, optimized for flexible and high-throughput operation. The three-chamber system, used here for oxide growth, consists of a sample loading chamber, a storage chamber, and a growth chamber. The growth chamber is equipped with eight identical effusion cell ports with linear shutters, one larger port for either a multi-pocket electron beam evaporator or an oxygen plasma source, an integrated cryoshroud, retractable beam-flux monitor or quartz-crystal microbalance, reflection high energy electron diffraction, substrate manipulator, main shutter, and quadrupole mass spectrometer. The system can be combined with ultrahigh vacuum (UHV) end stations on synchrotron and neutron beamlines, or equivalently with other complex surface analysis systems, including low-temperature scanning probe microscopy systems. Substrate handling is compatible with most UHV surface characterization systems, as the miniMBE can accommodate standard surface science sample holders. We introduce the design of the system, and its specific capabilities and operational parameters, and we demonstrate the epitaxial thin film growth of magnetoelectric Cr 2 O 3 on c -plane sapphire and ferrimagnetic Fe 3 O 4 on MgO (001).
    Print ISSN: 0034-6748
    Electronic ISSN: 1089-7623
    Topics: Electrical Engineering, Measurement and Control Technology , Physics
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  • 7
    Publication Date: 2016-03-25
    Description: We outline a modeling study of an extrinsic semiconductor interface formed from the interaction of nanostructured metal oxide decorated porous silicon and used for sensing gas phase analytes. We consider simple conductometric sensors that operate at room temperature and atmospheric pressure. Nanostructured metal oxide deposition provides a matrix of responses to various analytes, facilitating the extraction of ambient gas concentrations from sensor responses. The sensors are simulated in four stages with an emphasis to the continual improvement of the modeling effort. Stage 1 focuses solely on the diffusion mechanics of an analyte gas into and out of a micro/nanoporous interface and the observed linear response at low concentrations. Stage 2 focuses on the non-linearity resulting primarily from the quenching of sensor response at higher concentrations and introduces an absorption response mechanism. Here, stage 3 demonstrates how the consideration of charge carrier density leads to the development of a new Fermi-distribution based response mechanism. Stage 4 establishes a combined absorption-Fermi-distribution response mechanism.
    Print ISSN: 0021-8979
    Electronic ISSN: 1089-7550
    Topics: Physics
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  • 8
    Publication Date: 2015-12-11
    Description: Experimental results from indirectly driven ignition implosions during the National Ignition Campaign (NIC) [M. J. Edwards et al ., Phys. Plasmas 20 , 070501 (2013)] achieved a record compression of the central deuterium-tritium fuel layer with measured areal densities up to 1.2 g/cm 2 , but with significantly lower total neutron yields (between 1.5 × 10 14 and 5.5 × 10 14 ) than predicted, approximately 10% of the 2D simulated yield. An order of magnitude improvement in the neutron yield was subsequently obtained in the “high-foot” experiments [O. A. Hurricane et al ., Nature 506 , 343 (2014)]. However, this yield was obtained at the expense of fuel compression due to deliberately higher fuel adiabat. In this paper, the design of an adiabat-shaped implosion is presented, in which the laser pulse is tailored to achieve similar resistance to ablation-front instability growth, but with a low fuel adiabat to achieve high compression. Comparison with measured performance shows a factor of 3–10× improvement in the neutron yield (〉40% of predicted simulated yield) over similar NIC implosions, while maintaining a reasonable fuel compression of 〉1 g/cm 2 . Extension of these designs to higher laser power and energy is discussed to further explore the trade-off between increased implosion velocity and the deleterious effects of hydrodynamic instabilities.
    Print ISSN: 1070-664X
    Electronic ISSN: 1089-7674
    Topics: Physics
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  • 9
    Publication Date: 2016-04-02
    Description: A series of indirectly driven capsule implosions has been performed on the National Ignition Facility to assess the relative contributions of ablation-front instability growth vs. fuel compression on implosion performance. Laser pulse shapes for both low and high-foot pulses were modified to vary ablation-front growth and fuel adiabat, separately and controllably. Three principal conclusions are drawn from this study: (1) It is shown that reducing ablation-front instability growth in low-foot implosions results in a substantial (3-10X) increase in neutron yield with no loss of fuel compression. (2) It is shown that reducing the fuel adiabat in high-foot implosions results in a significant (36%) increase in fuel compression together with a small (10%) increase in neutron yield. (3) Increased electron preheat at higher laser power in high-foot implosions, however, appears to offset the gain in compression achieved by adiabat-shaping at lower power. These results taken collectively bridge the space between the higher compression low-foot results and the higher yield high-foot results.
    Print ISSN: 1070-664X
    Electronic ISSN: 1089-7674
    Topics: Physics
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  • 10
    Publication Date: 2019
    Description: 〈div data-abstract-type="normal"〉〈p〉We experimentally investigate the two-phase interplay in an open-channel turbulent boundary layer laden with finite-size particles at global volume fractions between 4 and 25 %. The working fluid (water) and the dispersed phase (hydrogel spheres) have closely matched refractive indices, allowing us to measure the properties of both phases using particle image velocimetry and particle tracking velocimetry, respectively. The particles have a diameter of approximately 9 % of the channel depth and are slightly denser than the fluid. The negative buoyancy causes a strong vertical concentration gradient, characterized by discrete and closely spaced particle layers parallel to the wall. Even at the lowest considered volume fractions, the near-wall fluid velocity and velocity gradients are strongly reduced, with large mean shear throughout most of the channel height. This indicates that the local effective viscosity of the suspension is greatly increased due to the friction between particle layers sliding over one another. The particles consistently lag the fluid and leave their footprint on its mean and fluctuating velocity profiles. The turbulent activity is damped near the wall, where the nearly packed particles disrupt and suppress large-scale turbulent fluctuations and redistribute some of the kinetic energy to smaller scales. On the other hand, in the outer region of the flow where the local particle concentration is low, the mean shear produces strong Reynolds stresses, with enhanced sweeps and ejections and frequent swirling events.〈/p〉〈/div〉
    Print ISSN: 0022-1120
    Electronic ISSN: 1469-7645
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics , Physics
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