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  • Aerospace Medicine; Statistics and Probability; Computer Programming and Software  (1)
  • Computer Programming and Software; Statistics and Probability; Aerospace Medicine  (1)
  • 2015-2019  (2)
  • 1960-1964
  • 1935-1939
  • 1910-1914
  • 1
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    Integrated Medical Model (IMM) Optimization Version 4.0 Functional Improvements (2016)
    In:  CASI
    Details
    Publication Date: 2019-07-13
    Description: The IMMs ability to assess mission outcome risk levels relative to available resources provides a unique capability to provide guidance on optimal operational medical kit and vehicle resources. Post-processing optimization allows IMM to optimize essential resources to improve a specific model outcome such as maximization of the Crew Health Index (CHI), or minimization of the probability of evacuation (EVAC) or the loss of crew life (LOCL). Mass and or volume constrain the optimized resource set. The IMMs probabilistic simulation uses input data on one hundred medical conditions to simulate medical events that may occur in spaceflight, the resources required to treat those events, and the resulting impact to the mission based on specific crew and mission characteristics. Because IMM version 4.0 provides for partial treatment for medical events, IMM Optimization 4.0 scores resources at the individual resource unit increment level as opposed to the full condition-specific treatment set level, as done in version 3.0. This allows the inclusion of as many resources as possible in the event that an entire set of resources called out for treatment cannot satisfy the constraints. IMM Optimization version 4.0 adds capabilities that increase efficiency by creating multiple resource sets based on differing constraints and priorities, CHI, EVAC, or LOCL. It also provides sets of resources that improve mission-related IMM v4.0 outputs with improved performance compared to the prior optimization. The new optimization represents much improved fidelity that will improve the utility of the IMM 4.0 for decision support.
    Keywords: Aerospace Medicine; Statistics and Probability; Computer Programming and Software
    Type: GRC-E-DAA-TN29567 , 2016 NASA Human Research Program Investigators'' Workshop (HRP IWS 2016); Feb 08, 2016 - Feb 11, 2016; Galveston, TX; United States
    Format: application/pdf
    Location Call Number Expected Availability
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  • 2
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    Integrated Medical Model (IMM) 4.0 Enhanced Functionalities (2015)
    In:  CASI
    Details
    Publication Date: 2019-07-13
    Description: The Integrated Medical Model is a probabilistic simulation model that uses input data on 100 medical conditions to simulate expected medical events, the resources required to treat, and the resulting impact to the mission for specific crew and mission characteristics. The newest development version of IMM, IMM v4.0, adds capabilities that remove some of the conservative assumptions that underlie the current operational version, IMM v3. While IMM v3 provides the framework to simulate whether a medical event occurred, IMMv4 also simulates when the event occurred during a mission timeline. This allows for more accurate estimation of mission time lost and resource utilization. In addition to the mission timeline, IMMv4.0 features two enhancements that address IMM v3 assumptions regarding medical event treatment. Medical events in IMMv3 are assigned the untreated outcome if any resource required to treat the event was unavailable. IMMv4 allows for partially treated outcomes that are proportional to the amount of required resources available, thus removing the dichotomous treatment assumption. An additional capability IMMv4 is to use an alternative medical resource when the primary resource assigned to the condition is depleted, more accurately reflecting the real-world system. The additional capabilities defining IMM v4.0the mission timeline, partial treatment, and alternate drug result in more realistic predicted mission outcomes. The primary model outcomes of IMM v4.0 for the ISS6 mission, including mission time lost, probability of evacuation, and probability of loss of crew life, are be compared to those produced by the current operational version of IMM to showcase enhanced prediction capabilities.
    Keywords: Computer Programming and Software; Statistics and Probability; Aerospace Medicine
    Type: GRC-E-DAA-TN20329 , Space Radiation Investigators'' Workshop and Behavioral Health and Performance Working Group; Jan 12, 2015 - Jan 15, 2015; Galveston, TX; United States|NASA Human Research Program Investigators'' Workshop: Integrated Pathways to Mars; Jan 13, 2015 - Jan 15, 2015; Galveston, TX; United States
    Format: application/pdf
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    NASA TECHNICAL REPORTS
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