Publikationsdatum:
2015-07-11
Beschreibung:
Article G-quadruplexes formed by four guanine bases in a square planar arrangement in telomeres may prevent extension of this region by telomerase. Here, the authors show that telomerase can localize to and partially unwind and extend G-quadruplexes, suggesting an important biological role for G-quadruplexes. Nature Communications doi: 10.1038/ncomms8643 Authors: Aaron L. Moye, Karina C. Porter, Scott B. Cohen, Tram Phan, Katherine G. Zyner, Natsuki Sasaki, George O. Lovrecz, Jennifer L. Beck, Tracy M. Bryan
Digitale ISSN:
2041-1723
Thema:
Biologie
,
Chemie und Pharmazie
,
Allgemeine Naturwissenschaft
,
Physik
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