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  • Articles  (40)
  • Wiley  (36)
  • American Society of Hematology
  • 2015-2019  (26)
  • 1985-1989  (14)
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  • Articles  (40)
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  • 1
    Publication Date: 2016-11-01
    Print ISSN: 0361-5995
    Electronic ISSN: 1435-0661
    Topics: Geosciences , Agriculture, Forestry, Horticulture, Fishery, Domestic Science, Nutrition
    Published by Wiley
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  • 2
    Publication Date: 2015-12-29
    Description: Remnants of ancient retroviral infections during evolution litter all mammalian genomes. In modern humans, such endogenous retroviral (ERV) sequences comprise at least 8% of the genome. While ERVs and other types of transposable elements undoubtedly contribute to the genomic “junk yard”, functions for some ERV sequences have been demonstrated, with growing evidence that ERVs can be important players in gene regulatory processes. Here we focus on one particular large family of human ERVs, termed HERVH, which several recent studies suggest has a key regulatory role in human pluripotent stem cells. Remarkably, this is not the first instance of an ERV controlling pluripotency. We speculate as to why this convergent evolution might have come about, suggesting that it may reflect selection on the virus to extend the time available for transposition. Alternatively it may reflect serendipity alone. Our genome harbors ∼2000 copies of the retroviral element HERVH, which have accumulated by infections and retrotranspositions over time. This endogenization process resulted in some HERVH copies acquiring a domesticated cellular function. In primates, HERVH drives a regulatory network modulating pluripotency. We ask why similar events occur repeatedly during evolution.
    Print ISSN: 0265-9247
    Electronic ISSN: 1521-1878
    Topics: Biology , Medicine
    Published by Wiley
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  • 3
    Publication Date: 2015-04-17
    Description: Quarter-wave modes are standing shear Alfvén waves supported along geomagnetic field lines in space. They are predicted to be generated when the ionosphere has very different conductance between the north compared with the south ionosphere. Our previous observation reported that the resonant frequency is sometimes very low around the dawn terminator and suggested these were due to quarter-wave modes. In this paper, we examine the resonance structure that provides further evidence of the presence of quarter-wave modes. Data from three magnetometers in New Zealand were analyzed. Four events are discussed which show extraordinarily low eigenfrequencies, wide resonance widths, and strong damping when the ionosphere above New Zealand was in darkness while the conjugate northern hemisphere ionosphere was sunlit. Later in the morning the eigenfrequencies and resonance widths changed to normal daytime values. The wide resonance width and the strong damping of the quarter-wave modes arise from strong energy dissipation in the dark side ionosphere. One event exhibited field line resonance structure continuously through a transition from very low frequency to the normal daytime values. The frequency change began when the dawn terminator passed over New Zealand and finished one hour later when the ratio of the inter-hemispheric ionospheric conductances decreased and reached ~5. These observations are strong evidence of the presence of quarter-wave modes and mode conversion from quarter to half wave resonances. These experimental results were compared with the ULF wave fields obtained from a 2.5-dimensional simulation model.
    Print ISSN: 0148-0227
    Topics: Geosciences , Physics
    Published by Wiley on behalf of American Geophysical Union (AGU).
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  • 4
    Publication Date: 2015-05-21
    Description: ABSTRACT The ridgelines of mountain ranges are a source of geomorphic information unadulterated by the arrival of sediment from upslope. Studies along ridgecrests, therefore, can help identify and isolate the controls on important regolith properties such as thickness and texture. A 1.5-km section of ridgeline in the Sierra Nevada (CA) with a tenfold decrease in erosion rate (inferred from ridgetop convexity) provided an opportunity to conduct a high-resolution survey of regolith properties and investigate their controls. We found that regolith along the most quickly eroding section of the ridge was the rockiest and had the lowest clay concentrations. Furthermore, a general increase in regolith thickness with a slowing of erosion rate was accompanied by an increase in biomass, changes in vegetation community, broader ridgeline profiles, and an apparent increase in total available moisture. The greatest source of variation in regolith thickness at the 10–100-m scale, however, was the local topography along the ridgeline, with the deepest regolith in the saddles and the thinnest on the knobs. Because regolith in the saddles had higher surface soil moisture than the knobs, we conclude that the hydrological conditions primarily driven by local topography (i.e., rapid vs. slow drainage and water-storage potential) provide the fundamental controls on regolith thickness through feedbacks incorporating physical weathering by the biota and chemical weathering. Moreover, because the ridgeline saddles are the uppermost extensions of 1 st -order valleys, we propose that the fluvial network affects regolith properties in the furthest reaches of the watershed. This article is protected by copyright. All rights reserved.
    Print ISSN: 0197-9337
    Electronic ISSN: 1096-9837
    Topics: Geography , Geosciences
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  • 5
    Publication Date: 2015-12-12
    Description: ABSTRACT Hillslope length is a fundamental attribute of landscapes, intrinsically linked to drainage density, landslide hazard, biogeochemical cycling and hillslope sediment transport. Existing methods to estimate catchment average hillslope lengths include inversion of drainage density or identification of a break in slope-area scaling, where the hillslope domain transitions into the fluvial domain. Here we implement a technique which models flow from point sources on hilltops across pixels in a digital elevation model (DEM), based on flow directions calculated using pixel aspect, until reaching the channel network, defined using recently developed channel extraction algorithms. Through comparisons between these measurement techniques, we show that estimating hillslope length from plots of topographic slope versus drainage area, or by inverting measures of drainage density, systematically underestimates hillslope length. In addition, hillslope lengths estimated by slope-area scaling breaks show large variations between catchments of similar morphology and area. We then use hillslope length – relief structure of landscapes to explore nature of sediment flux operating on a landscape. Distinct topographic forms are predicted for end-member sediment flux laws which constrain sediment transport on hillslopes as being linearly or nonlinearly dependent on hillslope gradient. Because our method extracts hillslope profiles originating from every ridgetop pixel in a DEM, we show that the resulting population of hillslope length – relief measurements can be used to differentiate between linear and nonlinear sediment transport laws in soil mantled landscapes. We find that across a broad range of sites across the continental United States, topography is consistent with a sediment flux law in which transport is nonlinearly proportional to topographic gradient. This article is protected by copyright. All rights reserved.
    Print ISSN: 0197-9337
    Electronic ISSN: 1096-9837
    Topics: Geography , Geosciences
    Published by Wiley
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  • 6
    Publication Date: 2019
    Description: Abstract Loessite present in a borehole into the Smith Bank Formation (early Triassic age, Central North Sea) differentiates five coeval source terranes for aerosol dust, three long distance sources and two local sources. All were active immediately following the end Permian mass extinction. Long distance sources are sedimentary, basic magmatic and acid–intermediate volcanic. Although predominantly silt‐sized and dominated by quartz with subordinate feldspars, muscovite and illite, evidence of basic and acid–intermediate magmatic/volcanic sources are pervasive. Baddeleyite is diagnostic of basic magmatism, an origin supported by enrichment of plagioclase relative to potassium feldspar. Deduction of acid–intermediate volcanism comes from the collective occurrence of irregular geometry quartz, volcanic shards, Ti‐mineralization, euhedral biotite, sanidine, the co‐occurrence of apatite and zircon, and the common occurrence of a tosuditic clay mineral. The tosuditic phase occurs as an unusual diagenetic dioctahedral chlorite/smectite formed at low temperature (〈45°C), during very shallow burial by the decomposition of unstable rhyo‐dacitic and andesitic grains in alkaline pore water from an adjacent lake that yielded pore fluids with a high Al:Si ratio. The Siberian Traps large igneous province is the likely source terrane for the magmatic and volcanic silt. Locally sourced clay pellets and kaolinite booklets formed from aeolian erosion of an adjacent, periodically desiccated lake‐floor and a kaolinitic regolith, respectively. Inference of a prolonged harsh, arid climate leaves no evidence of any periods of sustained humidity or climatic fluctuation, such as pedogenesis. The association between the end Permian mass extinction, emplacement and aeolian erosion of the Siberian Traps large igneous province, and location of the Smith Bank Formation in a large lacustrine endorheic basin, combine to preserve a record of prolonged harsh climate in the early Triassic. This article is protected by copyright. All rights reserved.
    Print ISSN: 0037-0746
    Electronic ISSN: 1365-3091
    Topics: Geosciences
    Published by Wiley
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  • 7
    Publication Date: 2016-11-08
    Description: Hexagonal BN is an unusual material in that it is both highly thermally conductive as well as an electrical insulator. Additionally, hBN is also thermally stable in air. This unusual combination of properties makes hBN of significant interest for thermal management. Unfortunately, hBN is not easily consolidated into substrates without the addition of second phases which generally result in poorer thermal performance. This research investigates the potential to utilize this material to dissipate heat from high-voltage, high-power electrical devices. Specifically, a process to coat individual platelets of commercial hexagonal BN powder with a layer of amorphous aluminum oxide was developed. The coated hexagonal BN was then hot-pressed to form a highly thermally conductive substrate. The process to coat hexagonal BN platelets with aluminum oxide was accomplished by mixing hexagonal BN with AlCl 3 containing some water, then evaporation of excess AlCl 3 to form a Al, Cl, and O layer on hexagonal BN. This product was then heated in air to convert the surface layer into aluminum oxide. Following hot pressing to-+50°C and 10 ksi, the consolidated composite has through-plane and in-plane thermal conductivity of 14 and 157 W·(m·K) −1 , respectively, at room temperature.
    Print ISSN: 0002-7820
    Electronic ISSN: 1551-2916
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
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  • 8
    Publication Date: 2017-04-25
    Description: Predominantly fine-grained strata were deposited in the Smith Bank Formation (Early Triassic) in the Central North Sea area of the Northern Permian Basin. Previously regarded as monotonous red claystone, examination of continuous core reveals abundant stratification, significant variation in colour, siltstone as the prevalent average grain size, and claystone is rare. Loessite occurs beyond the north-western lacustrine margin and aerosol dust has inundated clay pellets derived from aeolian reworking of the desiccated lake floor. The loessite has limited evidence of pluvial reworking but rare fossil roots testify to sufficient moisture to sustain plants. Loessite has not previously been successfully differentiated from other fine-grained strata in the subsurface but this study defines the presence of random grain-fabric orientation as an intrinsic unequivocal characteristic of loessite that formed during air-fall deposition of aerosol dust. Comparison with outcrop data verifies the utility of grain fabric to differentiate loessite. Tosudite, an aluminous di-octahedral regularly ordered mixed-layer chlorite/smectite, which is rare in sedimentary rock, forms a significant proportion (10 to 21%) of the clay mineral fraction of loessite along with a similar quantity of kaolinite. In all other samples, only illite and chlorite are identified, which is typical of fine-grained Triassic strata. In a location, close to the southern lake margin, lacustrine strata are characterised by fining-upward couplets of very-fine grained sandstone into siltstone and mudstone, with occasional desiccated surfaces. Small sand injections and associated sand extrusions are common and indicate periodic fluidisation of sand. Precise stratigraphic location of the Smith Bank Formation is problematic because of extremely sparse fossil preservation however there is no sedimentological evidence for a period of hyper-aridity known from the early Olenekian in continental Europe, which may mean that the North Permian Basin was never hyper-arid or that the Smith Bank Formation is restricted to the Induan. This article is protected by copyright. All rights reserved.
    Print ISSN: 0037-0746
    Electronic ISSN: 1365-3091
    Topics: Geosciences
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  • 9
    Publication Date: 2016-12-21
    Description: Fish and wildlife harvest management at large spatial scales often involves making complex decisions with multiple objectives and difficult tradeoffs, population demographics that vary spatially, competing stakeholder values, and uncertainties that might affect management decisions. Structured decision making (SDM) provides a formal decision analytic framework for evaluating difficult decisions by breaking decisions into component parts and separating the values of stakeholders from the scientific evaluation of management actions and uncertainty. The result is a rigorous, transparent, and values-driven process. This decision-aiding process provides the decision maker with a more complete understanding of the problem and the effects of potential management actions on stakeholder values, as well as how key uncertainties can affect the decision. We use a case study to illustrate how SDM can be used as a decision-aiding tool for management decision making at large scales. We evaluated alternative white-tailed deer ( Odocoileus virginianus ) buck-harvest regulations in New York designed to reduce harvest of yearling bucks, taking into consideration the values of the state wildlife agency responsible for managing deer, as well as deer hunters. We incorporated tradeoffs about social, ecological, and economic management concerns throughout the state. Based on the outcomes of predictive models, expert elicitation, and hunter surveys, the SDM process identified management alternatives that optimized competing objectives. The SDM process provided biologists and managers insight about aspects of the buck-harvest decision that helped them adopt a management strategy most compatible with diverse hunter values and management concerns.
    Electronic ISSN: 2150-8925
    Topics: Energy, Environment Protection, Nuclear Power Engineering
    Published by Wiley on behalf of The Ecological Society of America (ESA).
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  • 10
    Publication Date: 2015-11-14
    Description: We use a new exploratory model that simulates the evolution of sandy coastlines over decadal to centennial timescales to examine the behavior of crenulate-shaped bays forced by differing directional wave climates. The model represents the coastline as a vector in a Cartesian reference frame, and the shoreface evolves relative to its local orientation, allowing simulation of coasts with high planform-curvature. Shoreline change is driven by gradients in alongshore transport following newly developed algorithms that facilitate dealing with high planform-curvature coastlines. We simulated the evolution (over 100 years) of bays from a straight coast between two fixed headlands (2 km apart) with no external sediment inputs, to an equilibrium condition (zero net alongshore sediment flux) under an ensemble of directional wave climate conditions. We find that planform bay relief increases with obliquity of the mean wave direction, and decreases with the spread of wave directions. Varying bay size over two orders of magnitude (0.1-16 km), the model predicts bay shape to be independent of bay size. The time taken for modeled bays to attain equilibrium was found to scale with the square of the distance between headlands, so that, all else being equal, small bays are likely to respond to and recover from perturbations more rapidly (over just a few years) compared to large bays (hundreds of years). Empirical expressions predicting bay shape may be misleading if used to predict their behavior over planning timescales.
    Print ISSN: 0148-0227
    Topics: Geosciences , Physics
    Published by Wiley on behalf of American Geophysical Union (AGU).
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