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  • 1
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    HST imaging of the dusty filaments and nucleus swirl in NGC4696 at the centre of the Centaurus Cluster (2016)
    Oxford University Press
    Details
    Publikationsdatum: 2016-07-02
    Beschreibung: Narrow-band HST imaging has resolved the detailed internal structure of the 10 kpc diameter H α+[N  ii ] emission line nebulosity in NGC4696, the central galaxy in the nearby Centaurus cluster, showing that the dusty, molecular, filaments have a width of about 60 pc. Optical morphology and velocity measurements indicate that the filaments are dragged out by the bubbling action of the radio source as part of the active galactic nucleus feedback cycle. Using the drag force we find that the magnetic field in the filaments is in approximate pressure equipartition with the hot gas. The filamentary nature of the cold gas continues inwards, swirling around and within the Bondi accretion radius of the central black hole, revealing the magnetic nature of the gas flows in massive elliptical galaxies. HST imaging resolves the magnetic, dusty, molecular filaments at the centre of the Centaurus cluster to a swirl around and within the Bondi radius.
    Print ISSN: 0035-8711
    Digitale ISSN: 1365-2966
    Thema: Physik
    Publiziert von Oxford University Press
    Standort Signatur Erwartet Verfügbarkeit
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  • 2
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    Congenital poisoning by polychlorinated biphenyls and their contaminants in Taiwan (1988)
    American Association for the Advancement of Science (AAAS)
    Details
    Publikationsdatum: 1988-07-15
    Beschreibung: In 1979, a mass poisoning occurred in Taiwan from cooking oil contaminated by thermally degraded polychlorinated biphenyls. Because these chemicals persist in human tissue, children born to female patients after the outbreak were exposed in utero. In 1985, 117 children born to affected women and 108 unexposed controls were examined and evaluated. The exposed children were shorter and lighter than controls; they had abnormalities of gingiva, skin, nails, teeth, and lungs more frequently than did controls. The exposed children showed delay of developmental milestones, deficits on formal developmental testing, and abnormalities on behavioral assessment. These findings are most consistent with a generalized disorder of ectodermal tissue. This syndrome is one of very few documented to result from transplacental exposure to pollutant chemicals.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Rogan, W J -- Gladen, B C -- Hung, K L -- Koong, S L -- Shih, L Y -- Taylor, J S -- Wu, Y C -- Yang, D -- Ragan, N B -- Hsu, C C -- New York, N.Y. -- Science. 1988 Jul 15;241(4863):334-6.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉National Institute of Environmental Health Sciences, Research Triangle Park, NC 27709.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/3133768" target="_blank"〉PubMed〈/a〉
    Schlagwort(e): Conjunctivitis/chemically induced/congenital ; Female ; Growth Disorders/chemically induced ; Humans ; Lactation ; Maternal-Fetal Exchange ; Nails, Malformed ; Oils/*adverse effects ; Pigmentation Disorders/chemically induced/congenital ; Polychlorinated Biphenyls/*poisoning ; Pregnancy ; Taiwan
    Print ISSN: 0036-8075
    Digitale ISSN: 1095-9203
    Thema: Biologie , Chemie und Pharmazie , Informatik , Medizin , Allgemeine Naturwissenschaft , Physik
    Publiziert von American Association for the Advancement of Science (AAAS)
    Standort Signatur Erwartet Verfügbarkeit
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  • 3
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    Biomolecules. The dark side of sunlight and melanoma (2015)
    American Association for the Advancement of Science (AAAS)
    Details
    Publikationsdatum: 2015-02-24
    Beschreibung: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Taylor, John-Stephen -- New York, N.Y. -- Science. 2015 Feb 20;347(6224):824. doi: 10.1126/science.aaa6578.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Department of Chemistry, Washington University, St. Louis, MO 63130, USA. taylor@wustl.edu.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/25700500" target="_blank"〉PubMed〈/a〉
    Schlagwort(e): Animals ; DNA/*radiation effects ; DNA Damage/*genetics ; Humans ; Melanins/*metabolism ; Melanocytes/*radiation effects ; Melanoma/*genetics ; Neoplasms, Radiation-Induced/*genetics ; Pyrimidine Dimers/*metabolism ; Skin Neoplasms/*genetics
    Print ISSN: 0036-8075
    Digitale ISSN: 1095-9203
    Thema: Biologie , Chemie und Pharmazie , Informatik , Medizin , Allgemeine Naturwissenschaft , Physik
    Publiziert von American Association for the Advancement of Science (AAAS)
    Standort Signatur Erwartet Verfügbarkeit
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  • 4
    Digitale Medien
    Digitale Medien
    The role of plant hormones and carbohydrates in the growth and survival of coppiced Eucalyptus seedlings (1982)
    Oxford, UK : Blackwell Publishing Ltd
    Physiologia plantarum 55 (1982), S. 0 
    Details
    ISSN: 1399-3054
    Quelle: Blackwell Publishing Journal Backfiles 1879-2005
    Thema: Biologie
    Notizen: Depending on the species, coppicing (decapitation) may promote vigorous growth (Eucalyptus camaldulensis Dehn), or cause rapid senescence and death (Eucalyptus obliqua L'Herit). In seedlings of the latter species, the presence of a small upwardly directed shoot on the decapitated stump prevents or delays decline. Coppiced seedlings of E. camaldulensis and E. obliqua, with and without a remaining shoot, were analyzed for starch and soluble sugars (with the anthrone method), gibberellin-like substances (GAs) and cytokinin-like substances (by bioassay), and ethylene (by gas-liquid chromatography) before and after decapitation.Levels of soluble sugars declined similarly in both varieties of eucalypts, and starch reserves appeared adequate for sprouting, and did not diminish following decapitation of the susceptible species.Decapitation did not markedly alter the relatively high amounts of GAs in roots and shoots of E. obliqua, the susceptible species, although increased levels of Gas were observed in the stumps of seedlings left with 1 shoot after decapitation. The overall levels of GaS were relatively low in the roots and stems of the resistant E. camaldulensis, but higher in the shoots. Marked qualitative changes in GAs with decapitation were apparent in the shoots of E. camaldulensis. A single major GA peak occurred prior to decapitation but afer decapitation several additional peaks of GA-like activity appeared.Cytokinin-like activity was initially low in all tissues, but increased dramatically in stump and shoot tissue following decapitation. Increases ranged from approximately 5-fold (stump tissue of either species, minus-shoot treatment) to approximately 40-fold (shoot tissue of the resistant E. camaldulensis seedlings left with 1 shoot). In both E. camaldulensis and E. obliqua ethylene production increased to a peak 7 days after decapitation provided a shoot had been retained. This ethylene peak precedes a marked upturning of the retained shoot, and was not present in the stumps of totally decapitated seedlings. For totally decapitated seedlings ethylene evolution in E. obliqua (the susceptible species), but not E. camaldulensis (the resistant species), had ceased by 15 days.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1111/j.1399-3054.1982.tb04522.x
    Standort Signatur Erwartet Verfügbarkeit
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  • 5
    Digitale Medien
    Digitale Medien
    Changes in endogenous hormones in apple during bud burst induced by defoliation (1984)
    Springer
    Plant growth regulation 2 (1984), S. 117-134 
    Details
    ISSN: 1573-5087
    Schlagwort(e): Abscisic acid ; apple ; bud burst ; cytokinins ; defoliation ; gibberellins ; tropical horticulture
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Land- und Forstwirtschaft, Gartenbau, Fischereiwirtschaft, Hauswirtschaft
    Notizen: Abstract Under the tropical conditions of East Java, terminal buds of apple burst at any time of the year in response to removal of the subtending leaves. Following two such defoliations, two weeks apart on separate trees, there was a decrease in abscisic acid (ABA), a three-fold increase in gibberellin-like substances (GAs) and only a slight increase in cytokinin-like substances (CKs) in the apex tissue of closed buds. These changes preceded bud opening and the associated increases in fresh and dry weight, and may be causally related to bud burst. In open buds (i.e. young expanding leaves) the concentration of CKs was greater, and the concentrations of ABA and GAs less, than the concentrations in closed buds. As the leaves expanded, ABA increased and GAs and CKs decreased in concentration. The decrease in concentration of GAs and CKs, however, was due to the rise in dry weight of the expanding tissue; the amounts of all three hormones (per apex) increased. During bud burst there was a concurrent decrease in the CKs of subtending stems, suggesting a transfer into the expanding bud tissues. Removal of the old leaves by defoliation may remove the source of ABA and allow the amount of GAs in the apex to rise, bud burst following. Stem CKs may be utilized in the expansion of the new leaves in the bursting buds.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1007/BF00024860
    Standort Signatur Erwartet Verfügbarkeit
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  • 6
    Digitale Medien
    Digitale Medien
    The effect of drought on levels of abscisic acid, cytokinins, gibberellins and ethylene in aeroponically-grown sunflower plants (1986)
    Springer
    Plant growth regulation 4 (1986), S. 139-151 
    Details
    ISSN: 1573-5087
    Schlagwort(e): Abscisic acid ; cytokinins ; drought ; ethylene ; gibberellins ; sunflower ; water stress ; aeroponics ; roots ; shoots
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Land- und Forstwirtschaft, Gartenbau, Fischereiwirtschaft, Hauswirtschaft
    Notizen: Abstract Abscisic acid (ABA), cytokinins and gibberellin-like substances (GAs) were extracted from the roots and shoots of 17-day-old sunflower seedlings which had been droughted or were unstressed. Plants were grown in an aeroponic chamber which allowed for good control over degree of water stress and easy access to roots. Following methanolic extraction of lyophilized material, cytokinins were separated from the acidic growth-regulators on a cellulose PO4 cationic exchange column. The cytokinins were analysed by paper chromatography and HPLC and the soybean hypocotyl section assay. Semipurified acidic regulators were chromatographed on SiO2 columns and HPLC and aliquots assayed with the dwarf rice cv. Tan-ginbozu bioassay for GAs. Fractions known to contain ABA were purified by sequential reverse-phase HPLC of the acid and then of the methyl ester forms followed by quantitation as Me-ABA on GLC-EC. ABA losses were measured by using an internal standard [3H]-ABA). Ethylene production was also monitored in stressed and unstressed seedlings. The effect of drought on GAs and ethylene was minimal. The ABA levels were markedly higher in droughted plants. Stressed roots had 32 times more ABA than controls. The levels of cytokinins in the shoots of droughted plants were about half those in unstressed shoots, and qualitative differences occurred in the roots. Under stress a large peak of activity was present similar to zeatin glucoside which was not present in the unstressed condition. The results are discussed in relation to drought-effects on metabolism.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1007/BF00025195
    Standort Signatur Erwartet Verfügbarkeit
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  • 7
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    Mapping visual symbols onto spoken language along the ventral visual stream (2019)
    National Academy of Sciences
    Details
    Publikationsdatum: 2019-08-19
    Beschreibung: Reading involves transforming arbitrary visual symbols into sounds and meanings. This study interrogated the neural representations in ventral occipitotemporal cortex (vOT) that support this transformation process. Twenty-four adults learned to read 2 sets of 24 novel words that shared phonemes and semantic categories but were written in different artificial orthographies. Following 2 wk of training, participants read the trained words while neural activity was measured with functional MRI. Representational similarity analysis on item pairs from the same orthography revealed that right vOT and posterior regions of left vOT were sensitive to basic visual similarity. Left vOT encoded letter identity and representations became more invariant to position along a posterior-to-anterior hierarchy. Item pairs that shared sounds or meanings, but were written in different orthographies with no letters in common, evoked similar neural patterns in anterior left vOT. These results reveal a hierarchical, posterior-to-anterior gradient in vOT, in which representations of letters become increasingly invariant to position and are transformed to convey spoken language information.
    Print ISSN: 0027-8424
    Digitale ISSN: 1091-6490
    Thema: Biologie , Medizin , Allgemeine Naturwissenschaft
    Publiziert von National Academy of Sciences
    Standort Signatur Erwartet Verfügbarkeit
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  • 8
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    Regulation of intracellular pH by human peripheral blood lymphocytes as measured by 19F NMR. (1982)
    National Academy of Sciences
    Details
    Publikationsdatum: 1982-12-01
    Print ISSN: 0027-8424
    Digitale ISSN: 1091-6490
    Thema: Biologie , Medizin , Allgemeine Naturwissenschaft
    Publiziert von National Academy of Sciences
    Standort Signatur Erwartet Verfügbarkeit
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  • 9
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    Measuring the mechanical properties of molecular conformers (2015)
    Springer Nature
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    Publikationsdatum: 2015-09-23
    Beschreibung: Article Manipulation of single molecules can be achieved using scanning probe microscopy but the influence of molecular conformation on this process has, until now, been unclear. Here, the authors probe two different types of porphyrin conformer on a surface and see strong differences in their mechanochemical response. Nature Communications doi: 10.1038/ncomms9338 Authors: S. P. Jarvis, S. Taylor, J. D. Baran, N. R. Champness, J. A. Larsson, P. Moriarty
    Digitale ISSN: 2041-1723
    Thema: Biologie , Chemie und Pharmazie , Allgemeine Naturwissenschaft , Physik
    Publiziert von Springer Nature
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  • 10
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    Thyroid hormone signaling specifies cone subtypes in human retinal organoids (2018)
    American Association for the Advancement of Science (AAAS)
    In: Science
    Details
    Publikationsdatum: 2018-10-12
    Beschreibung: The mechanisms underlying specification of neuronal subtypes within the human nervous system are largely unknown. The blue (S), green (M), and red (L) cones of the retina enable high-acuity daytime and color vision. To determine the mechanism that controls S versus L/M fates, we studied the differentiation of human retinal organoids. Organoids and retinas have similar distributions, expression profiles, and morphologies of cone subtypes. S cones are specified first, followed by L/M cones, and thyroid hormone signaling controls this temporal switch. Dynamic expression of thyroid hormone–degrading and –activating proteins within the retina ensures low signaling early to specify S cones and high signaling late to produce L/M cones. This work establishes organoids as a model for determining mechanisms of human development with promising utility for therapeutics and vision repair.
    Schlagwort(e): Development, Online Only
    Print ISSN: 0036-8075
    Digitale ISSN: 1095-9203
    Thema: Biologie , Chemie und Pharmazie , Geologie und Paläontologie , Informatik , Medizin , Allgemeine Naturwissenschaft , Physik
    Publiziert von American Association for the Advancement of Science (AAAS)
    Standort Signatur Erwartet Verfügbarkeit
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