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  • Artikel  (105)
  • 2015-2019  (58)
  • 1990-1994  (47)
  • Informatik  (63)
  • Mathematik  (42)
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  • Artikel  (105)
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  • 11
    Digitale Medien
    Digitale Medien
    Springer
    Biological cybernetics 69 (1993), S. 183-193 
    ISSN: 1432-0770
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Biologie , Informatik , Physik
    Notizen: Abstract It is well known that the motor systems of animals are controlled by a hierarchy consisting of a brain, central pattern generator, and effector organs. An animal's walking patterns change depending on its walking velocities, even when it has been decerebrated, which indicates that the walking patterns may, in fact, be generated in the subregions of the neural systems of the central pattern generator and the effector organs. In order to explain the self-organization of the walking pattern in response to changing circumstances, our model incorporates the following ideas: (1) the brain sends only a few commands to the central pattern generator (CPG) which act as constraints to self-organize the walking patterns in the CPG; (2) the neural network of the CPG is composed of oscillating elements such as the KYS oscillator, which has been shown to simulate effectively the diversity of the neural activities; and (3) we have introduced a rule to coordinate leg movement, in which the excitatory and inhibitory interactions among the neurons act to optimize the efficiency of the energy transduction of the effector organs. We describe this mechanism as “the least dissatisfaction for the greatest number of elements”, which is a self-organization rule in the generation of walking patterns. By this rule, each leg tends to share the load as efficiently as possible under any circumstances. Using this self-organizing model, we discuss the control mechanism of walking patterns.
    Materialart: Digitale Medien
    Standort Signatur Erwartet Verfügbarkeit
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  • 12
    Digitale Medien
    Digitale Medien
    Springer
    Biological cybernetics 70 (1994), S. 505-512 
    ISSN: 1432-0770
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Biologie , Informatik , Physik
    Notizen: Abstract Insects generate walking patterns which depend upon external conditions. For example, when an insect is exposed to an additional load parallel to the direction in which it is walking, the walking pattern changes according to the magnitude of the load. Furthermore, even after some of its legs have been amputated, an insect will produce walking patterns with its remaining legs. These adaptations in insect walking could not previously be explained by a mathematical model, since the mathematical models were based upon the hypothesis that the relationship between walking velocity and walking patterns is fixed under all conditions. We have produced a mathematical model which describes self-organizing insect walking patterns in real-time by using feedback information regarding muscle load (Kimura et al. 1993). As part of this model, we introduced a new rule to coordinate leg movement, in which the information is circulated to optimize the efficiency of the energy transduction of each effector organ. We describe this mechanism as ‘the least dissatisfaction for the greatest number of elements’. In this paper, we introduce the following aspects of this model, which reflect adaptability to changing circumstances: (1) after one leg is exposed to a transient perturbation, the walking pattern recovers swiftly; (2) when the external load parallel to the walking direction is continuously increased or decreased, the pattern transition point is shifted according to the magnitude of the load increment or decrement. This model generates a walking pattern which optimizes energy consumption at a given walking velocity even under these conditions; and (3) when some of the legs are amputated, the model generates walking patterns which are consistent with experimental results. We also discuss the ability of a hierarchical self-organizing model to describe a swift and flexible information processing system.
    Materialart: Digitale Medien
    Standort Signatur Erwartet Verfügbarkeit
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  • 13
    Digitale Medien
    Digitale Medien
    Springer
    International journal of computer vision 9 (1992), S. 31-53 
    ISSN: 1573-1405
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Informatik
    Notizen: Abstract Integration of 21/2D sketches obtained at different observation stations into a consistent world (or object) representation is one of the central issues in computer vision and robotics. The resolution and accuracy of 21/2D sketches may be different from one view point to another, and inconsistent data between different observations may occur. This article presents an approach to building a spatiotemporal representation of dynamic scenes including moving objects from a sequence of range images taken by a moving observer. A range image is transformed into a height-map representation, which is segmented into the ground plane and objects on it. In order to capture the resolution and accuracy of the range information and the consistency of the height information between different height maps, we define a reliability measure of the height information for each bucket on the height map. Using this reliability, the system finds the correspondences of both static and moving objects between different observations, and successively refines the height information and its reliability with newly acquired data, dealing with inconsistent data. Final representation of the integrated height map consists of the time stamp of the last observation, region labels of static and moving objects and their spatiotemporal properties such as height information, its reliability, and the velocities of both the observer and independently moving objects. We applied the method to road scenes physically simulated by landscape toy models and show the experimental results.
    Materialart: Digitale Medien
    Standort Signatur Erwartet Verfügbarkeit
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  • 14
    facet.materialart.
    Unbekannt
    Oxford University Press
    Publikationsdatum: 2015-05-12
    Beschreibung: Motivation: Sequence-variation analysis is conventionally performed on mapping results that are highly redundant and occasionally contain undesirable heuristic biases. A straightforward approach to single-nucleotide polymorphism (SNP) analysis, using the Burrows–Wheeler transform (BWT) of short-read data, is proposed. Results: The BWT makes it possible to simultaneously process collections of read fragments of the same sequences; accordingly, SNPs were found from the BWT much faster than from the mapping results. It took only a few minutes to find SNPs from the BWT (with a supplementary data, fragment depth of coverage [FDC]) using a desktop workstation in the case of human exome or transcriptome sequencing data and 20 min using a dual-CPU server in the case of human genome sequencing data. The SNPs found with the proposed method almost agreed with those found by a time-consuming state-of-the-art tool, except for the cases in which the use of fragments of reads led to sensitivity loss or sequencing depth was not sufficient. These exceptions were predictable in advance on the basis of minimum length for uniqueness (MLU) and FDC defined on the reference genome. Moreover, BWT and FDC were computed in less time than it took to get the mapping results, provided that the data were large enough. Availability and implementation: A proof-of-concept binary code for a Linux platform is available on request to the corresponding author. Contact: kouichi.kimura.hh@hitachi.com Supplementary information: Supplementary data are available at Bioinformatics online.
    Print ISSN: 1367-4803
    Digitale ISSN: 1460-2059
    Thema: Biologie , Informatik , Medizin
    Publiziert von Oxford University Press
    Standort Signatur Erwartet Verfügbarkeit
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  • 15
    Publikationsdatum: 2019
    Beschreibung: We propose an extended scheme for selecting related stocks for themed mutual funds. This scheme was designed to support fund managers who are building themed mutual funds. In our preliminary experiments, building a themed mutual fund was found to be quite difficult. Our scheme is a type of natural language processing method and based on words extracted according to their similarity to a theme using word2vec and our unique similarity based on co-occurrence in company information. We used data including investor relations and official websites as company information data. We also conducted several other experiments, including hyperparameter tuning, in our scheme. The scheme achieved a 172% higher F1 score and 21% higher accuracy than a standard method. Our research also showed the possibility that official websites are not necessary for our scheme, contrary to our preliminary experiments for assessing data collaboration.
    Digitale ISSN: 2078-2489
    Thema: Informatik
    Publiziert von MDPI
    Standort Signatur Erwartet Verfügbarkeit
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  • 16
    Publikationsdatum: 1991-01-01
    Print ISSN: 0031-3203
    Digitale ISSN: 1873-5142
    Thema: Informatik
    Publiziert von Elsevier
    Standort Signatur Erwartet Verfügbarkeit
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  • 17
    Publikationsdatum: 1990-03-16
    Beschreibung: Prothoracicotropic hormone (PTTH), a brain secretory polypeptide of insects, stimulates the prothoracic glands to produce and release ecdysone, the steroid essential to insect development. The complementary DNAs encoding PTTH of the silkmoth Bombyx mori were cloned and characterized, and the complete amino acid sequence was deduced. The data indicated that PTTH is first synthesized as a 224-amino acid polypeptide precursor containing three proteolytic cleavage signals. The carboxyl-terminal component (109 amino acids) that follows the last cleavage signal represents one PTTH subunit. Two PTTH subunits are linked together by disulfide bonds, before or after cleavage from prepro-PTTH, to form a homodimeric PTTH. When introduced into Escherichia coli cells, the complementary DNA directed the expression of an active substance that was functionally indistinguishable from natural PTTH. In situ hybridization showed the localization of the prepro-PTTH mRNA to two dorsolateral neurosecretory cells of the Bombyx brain.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Kawakami, A -- Kataoka, H -- Oka, T -- Mizoguchi, A -- Kimura-Kawakami, M -- Adachi, T -- Iwami, M -- Nagasawa, H -- Suzuki, A -- Ishizaki, H -- New York, N.Y. -- Science. 1990 Mar 16;247(4948):1333-5.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Department of Biology, School of Science, Nagoya University, Japan.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/2315701" target="_blank"〉PubMed〈/a〉
    Schlagwort(e): Amino Acid Sequence ; Animals ; Base Sequence ; Bombyx/*genetics/physiology ; Cloning, Molecular ; DNA/genetics ; Gene Expression ; Insect Hormones/*genetics ; Molecular Sequence Data ; Neurosecretory Systems/physiology ; Nucleic Acid Hybridization ; Protein Precursors/genetics
    Print ISSN: 0036-8075
    Digitale ISSN: 1095-9203
    Thema: Biologie , Chemie und Pharmazie , Informatik , Medizin , Allgemeine Naturwissenschaft , Physik
    Standort Signatur Erwartet Verfügbarkeit
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  • 18
    Publikationsdatum: 1990-01-26
    Beschreibung: Endothelin (ET), originally characterized as a 21-residue vasoconstrictor peptide from endothelial cells, is present in the porcine spinal cord and may act as a neuropeptide. Endothelin-like immunoreactivity has now been demonstrated by immunohistochemistry in the paraventricular and supraoptic nuclear neurons and their terminals in the posterior pituitary of the pig and the rat. The presence of ET in the porcine hypothalamus was confirmed by reversed-phase high-pressure liquid chromatography and radioimmunoassay. Moreover, in situ hybridization demonstrated ET messenger RNA in porcine paraventricular nuclear neurons. Endothelin-like immunoreactive products in the posterior pituitary of the rat were depleted by water deprivation, suggesting a release of ET under physiological conditions. These findings indicate that ET is synthesized in the posterior pituitary system and may be involved in neurosecretory functions.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Yoshizawa, T -- Shinmi, O -- Giaid, A -- Yanagisawa, M -- Gibson, S J -- Kimura, S -- Uchiyama, Y -- Polak, J M -- Masaki, T -- Kanazawa, I -- New York, N.Y. -- Science. 1990 Jan 26;247(4941):462-4.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Department of Neurology, University of Tsukuba, Japan.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/2405487" target="_blank"〉PubMed〈/a〉
    Schlagwort(e): Animals ; Chromatography, High Pressure Liquid ; Endothelins ; Endothelium, Vascular ; Immunohistochemistry ; Male ; Neurons/analysis ; Nucleic Acid Hybridization ; Paraventricular Hypothalamic Nucleus/analysis ; Peptides/*analysis/genetics/metabolism ; Pituitary Gland/*analysis/metabolism ; RNA Probes ; RNA, Messenger/analysis ; Radioimmunoassay ; Rats ; Rats, Inbred Strains ; Supraoptic Nucleus/analysis ; Swine ; Tissue Distribution ; Water Deprivation
    Print ISSN: 0036-8075
    Digitale ISSN: 1095-9203
    Thema: Biologie , Chemie und Pharmazie , Informatik , Medizin , Allgemeine Naturwissenschaft , Physik
    Standort Signatur Erwartet Verfügbarkeit
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  • 19
    Publikationsdatum: 2016-03-17
    Beschreibung: This work is devoted to analyzing the feasibility study of a Moudafi viscosity projection method with a weak contraction for a finite family of quasinonexpansive mappings in a Hadamard space. To this end, we n...
    Print ISSN: 1687-1820
    Digitale ISSN: 1687-1812
    Thema: Mathematik
    Publiziert von Springer
    Standort Signatur Erwartet Verfügbarkeit
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  • 20
    Publikationsdatum: 1994-07-15
    Beschreibung: Dysfunction of the nigrostriatal dopamine system results in marked disorders of movement such as occur in Parkinson's disease. Functions of this dopamine-containing projection system were examined in monkeys trained in a classical conditioning task, and the effects of striatal dopamine depletion were tested. Unilateral dopamine loss substantially reduced the acquired sensory responsiveness of striatal neurons monitored electrophysiologically. This effect was ipsilateral and selective, and could be reversed by apomorphine. These results suggest that the primate nigrostriatal system modulates expression of neuronal response plasticity in the striatum during sensorimotor learning.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Aosaki, T -- Graybiel, A M -- Kimura, M -- R01 NS25529/NS/NINDS NIH HHS/ -- New York, N.Y. -- Science. 1994 Jul 15;265(5170):412-5.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Department of Brain and Cognitive Sciences, Massachusetts Institute of Technology, Cambridge 02139.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/8023166" target="_blank"〉PubMed〈/a〉
    Schlagwort(e): 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine/pharmacology ; Action Potentials/drug effects ; Animals ; Apomorphine/pharmacology ; *Behavior, Animal/drug effects ; *Conditioning, Classical ; Corpus Striatum/cytology/*physiology ; Dopamine/*physiology ; Haloperidol/pharmacology ; Macaca ; Male ; Neuronal Plasticity ; Neurons/drug effects/*physiology ; Substantia Nigra/cytology/physiology
    Print ISSN: 0036-8075
    Digitale ISSN: 1095-9203
    Thema: Biologie , Chemie und Pharmazie , Informatik , Medizin , Allgemeine Naturwissenschaft , Physik
    Standort Signatur Erwartet Verfügbarkeit
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