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  • 1
    Electronic Resource
    Electronic Resource
    Direct analysis of metal halides by electron-impact mass spectrometry (1971)
    s.l. : American Chemical Society
    Analytical chemistry 43 (1971), S. 1691-1692 
    Details
    ISSN: 1520-6882
    Source: ACS Legacy Archives
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1021/ac60306a032
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  • 2
    Electronic Resource
    Electronic Resource
    Direct determination of mercury halides by electron impact mass spectrometry (1972)
    s.l. : American Chemical Society
    Analytical chemistry 44 (1972), S. 2246-2247 
    Details
    ISSN: 1520-6882
    Source: ACS Legacy Archives
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1021/ac60321a031
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  • 3
    Electronic Resource
    Electronic Resource
    Living Anionic Ring-Opening Polymerization of 1,1-Dimethylsilacyclobutane (1995)
    s.l. : American Chemical Society
    Macromolecules 28 (1995), S. 7029-7031 
    Details
    ISSN: 1520-5835
    Source: ACS Legacy Archives
    Topics: Chemistry and Pharmacology , Physics
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1021/ma00124a048
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  • 4
    Electronic Resource
    Electronic Resource
    Digestion of staphylococcal enterotoxin by Bacillus natto (1997)
    Springer
    Antonie van Leeuwenhoek 71 (1997), S. 307-311 
    Details
    ISSN: 1572-9699
    Keywords: staphylococcal enterotoxins ; "natto' ; Bacillus natto ; subtilisin ; cooked rice
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Abstract Cooked rice contaminated with staphylococcal enterotoxin A (SEA) was mixed with 'natto', a Bacillus natto fermented soybean food, and the mixture was incubated at 37 °C for 1 h. Reversed passive latex agglutination (RPLA) tests performed on the mixture revealed that the RPLA titer against SEA was significantly reduced after incubation. Subsequent analytical tests showed that the SEA protein molecule was fragmented to small peptides by an extracellular protease, subtilisin, produced by B. natto. The proteolytic activity of B. natto was also found to be effective against ohter types of staphylococcal enterotoxins.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1023/A:1000131908089
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  • 5
    Electronic Resource
    Electronic Resource
    Anionic ring-opening polymerization of silacyclobutane derivatives (1997)
    Bognor Regis [u.a.] : Wiley-Blackwell
    Journal of Polymer Science Part A: Polymer Chemistry 35 (1997), S. 3207-3216 
    Details
    ISSN: 0887-624X
    Keywords: silacyclobutane ; poly(1,1-dimethylsilabutane) ; poly(1,1-diethylsilabutane) ; living polymerization ; block copolymer ; poly(1-methyl-1-phenylsilabutane) ; Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Notes: Anionic polymerizations of 1,1-dimethylsilacyclobutane, 1,1-diethylsilacyclobutane and 1-methyl-1-phenylsilacyclobutane were investigated. Addition of 5 mol % of butyllithium to a solution of 1,1-dimethylsilacyclobutane in THF-hexane (1 : 1) at -48°C provided poly(1,1-dimethylsilabutane) in 99% yield. Mn and Mw/Mn of the obtained polymer were 2400 and 1.10. This polymerization proceeded with a living nature. Mn increased in proportion as the yield of polymer increased. Addition of the second fresh feed of the monomer to the reaction mixture restarted polymerization of the second monomer at the same rate as in the initial stage. Addition of styrene to the living poly(1,1-dimethylsilabutane) provided a poly(1,1-dimethylsilabutane-b-styrene) block copolymer. It was also found that a polymerization of 1,1-diethylsilacyclobutane in THF-hexane at -48°C showed a living nature. In contrast, a polymerization of 1-methyl-1-phenylsilacyclobutane in THF at -78°C did not show a living nature. © 1997 John Wiley & Sons, Inc. J Polym Sci A: Polym Chem 35: 3207-3216, 1997
    Additional Material: 7 Ill.
    Type of Medium: Electronic Resource
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  • 6
    Electronic Resource
    Electronic Resource
    Synthesis of carbosilane block copolymers by means of a living anionic polymerization of 1,1-diethylsilacyclobutane (1998)
    Bognor Regis [u.a.] : Wiley-Blackwell
    Journal of Polymer Science Part A: Polymer Chemistry 36 (1998), S. 2699-2706 
    Details
    ISSN: 0887-624X
    Keywords: poly(1,1-diethylsilabutane) ; block copolymer ; polystyrene ; poly(4-hydroxystyrene) ; poly(methyl methacrylate) ; poly(2-hydroxyethyl methacrylate) ; Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Notes: Block polymerization of 1,1-diethylsilacyclobutane with styrene derivatives and methacrylate derivatives was investigated. Sequential addition of styrene to a living poly(1,1-diethylsilabutane), which was prepared from phenyllithium and 1,1-diethylsilacyclobutane in THF-hexane at -48°C, gave poly(1,1-diethylsilabutane)-b-polystyrene. Similarly, addition of 4-(tert-butyldimethylsiloxy)styrene to the living poly(1,1-diethylsilabutane) provided poly(1,1-diethylsilabutane)-b-poly(4-(tert-butyldimethylsiloxy)styrene). Poly(1,1-diethylsilabutane)-b-poly(methyl methacrylate) was obtained by treatment of living poly(1,1-diethylsilabutane) with 1,1-diphenylethylene followed by an addition of methyl methacrylate. Poly(1,1-diethylsilabutane)-b-poly(2-(tert-butyldimethylsiloxy)ethyl methacrylate) was also synthesized by adding 2-(tert-butyldimethylsiloxy)ethyl methacrylate to the living poly(1,1-diethylsilabutane) which was end-capped with 1,1-diphenylethylene in the presence of lithium chloride. © 1998 John Wiley & Sons, Inc. J Polym Sci A: Polym Chem 36: 2699-2706, 1998
    Additional Material: 5 Ill.
    Type of Medium: Electronic Resource
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  • 7
    Electronic Resource
    Electronic Resource
    Synthesis and characterization of polysilabutane having oligo(oxyethylene)phenyl groups on the silicon atom (1998)
    Bognor Regis [u.a.] : Wiley-Blackwell
    Journal of Polymer Science Part A: Polymer Chemistry 36 (1998), S. 225-231 
    Details
    ISSN: 0887-624X
    Keywords: silacyclobutane ; polysilabutane ; oligooxyethylene ; polycarbosilane ; anionic polymerization ; Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Notes: A new class of polar polysilabutanes with mono- or tri-(oxyethylene)phenyl groups on the silicon atom have been synthesized by anionic polymerization of silacyclobutanes having ω-(t-butyldimethylsilyl-protected) mono- or tri-(oxyethylene)phenyl groups and subsequent deprotection of the silyl groups. The monomers were synthesized by treatment of 1,1-dichlorosilacyclobutane with ω-(t-butyldimethylsilyl-protected) mono- or tri-(oxyethylene)phenyl Grignard reagents. Anionic polymerization of silacyclobutane was performed with butyllithium initiator in THF. t-Butyldimethylsilyl-protecting groups at polymer pendant groups were hydrolyzed with tetrabutyl ammonium fluoride in water-containing THF. The obtained polysilabutanes were soluble in a polar organic solvent such as methanol, and their mass distributions were analysed by matrix-assisted laser-desorption-ionization mass spectrometry (MALDI TOF MS). © 1998 John Wiley & Sons, Inc. J Polym Sci A: Polym Chem 36: 225-231, 1998
    Additional Material: 2 Ill.
    Type of Medium: Electronic Resource
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  • 8
    Electronic Resource
    Electronic Resource
    An integrated genetic map of the rat with 562 markers from different sources (1998)
    Springer
    Mammalian genome 9 (1998), S. 1002-1007 
    Details
    ISSN: 1432-1777
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Abstract. Genetic maps are the primary resources for genetic study. Genetic map construction was quite difficult in the past decade for lack of polymorphic markers. This situation has been changed since the development of microsatellite markers or simple sequence length polymorphisms (SSLPs) because they are abundant and more polymorphic. Here we report the construction of an integrated genetic map of the rat derived from two F2 intercrosses. A map of 376 markers from 160 (OLETF × F344)F2 progenies and a map of 333 markers from 71 (F344 × LEC)F2 animals are integrated by use of common set of 120 anchor markers chosen to be spaced at an average of 15 cM in the genome. The resulting integrated map with 194 newly developed rat markers from WIBR/MIT CGR, 269 Mit/Mgh markers, 94 Wox markers, and 5 markers of various origins covers the majority of 21 chromosomes of the rat with a total genetic distance of 1797 cM and an average marker spacing of 3.2 cM. The current map provides detailed information for markers from different sources and, therefore, should be helpful to the research community.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s003359900915
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  • 9
    Electronic Resource
    Electronic Resource
    Identification of novel non-insulin-dependent diabetes mellitus susceptibility loci in the Otsuka Long-Evans Tokushima Fatty rat by MQM-mapping method (1999)
    Springer
    Mammalian genome 10 (1999), S. 1126-1131 
    Details
    ISSN: 1432-1777
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Abstract. The Otsuka Long-Evans Tokushima Fatty (OLETF) rat is an animal model for obese-type, non-insulin-dependent diabetes mellitus (NIDDM) in humans. We have previously identified 11 quantitative trait loci (QTLs) responsible for NIDDM susceptibility on Chromosomes (Chrs) 1, 5, 7, 8, 9, 11, 12, 14, and 16 (Nidd1–11/of for Non-insulin-dependent diabetes1–11/oletf) by using the interval mapping method in 160 F2 progenies obtained by mating the OLETF and the Fischer-344 (F344) rats. MQM-mapping, which was applied for QTL analysis based on multiple-QTL models, is reported to be more powerful than interval mapping, because in the process of mapping one QTL the genetic background, which contains the other QTLs, is controlled. Application of MQM-mapping in the F2 intercrosses has led to a revelation of three novel QTLs on rat Chrs 5 (Nidd12/of), 7 (Nidd13/of), and 17 (Nidd14/of), in addition to Nidd1–11/of loci. The three QTLs, together with the Nidd1–11/of, account for a total of ∼70% and ∼85% of the genetic variance of the fasting and postprandial glucose levels, respectively, in the F2. While the OLETF allele corresponds with increased glucose levels as expected for Nidd12 and 14/of, the Nidd13/of exhibits heterosis: heterozygotes showing significantly higher glucose levels than OLETF or F344 homozygotes. There is epistatic interaction between Nidd2 and 14/of. Additionally, our results indicated that the novel QTLs could show no linkage with body weight, but Nidd12/of has an interaction with body weight.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s003359901177
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  • 10
    Electronic Resource
    Electronic Resource
    A major quantitative trait locus co-localizing with cholecystokinin type A receptor gene influences poor pancreatic proliferation in a spontaneously diabetogenic rat (1998)
    Springer
    Mammalian genome 9 (1998), S. 794-798 
    Details
    ISSN: 1432-1777
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Abstract. The Otsuka Long-Evans Tokushima Fatty (OLETF) rat is an animal model for obese-type, non-insulin-dependent diabetes mellitus (NIDDM) in humans. The OLETF rat has poor capacity for pancreatic proliferation, which may be the critical pathogenetic event in NIDDM development. Our investigation was designed to identify quantitative trait loci (QTLs) responsible for poor pancreatic proliferation by examining compensatory proliferation of the pancreatic remnant after partial pancreatectomy and performing a genome-wide scan in an F2 intercross obtained by mating the OLETF and the Fischer-344 (F344) rats. We identified a highly significant QTL on rat Chromosome 14 with a maximum lod score of 16.7, which accounts for 55% of the total variance. The QTL co-localizes with the gene encoding cholecystokinin type A receptor (CCKAR) which is likely to mediate the trophic effect of cholecystokinin on pancreas and is defective in the OLETF rat.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s003359900869
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