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  • Articles  (236)
  • Elsevier  (113)
  • Wiley  (56)
  • Springer Nature  (33)
  • Molecular Diversity Preservation International  (16)
  • Wiley-Blackwell  (12)
  • Society of Economic Geologists  (6)
  • 2015-2019  (145)
  • 1995-1999  (45)
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  • 1
    Publication Date: 2019-10-04
    Description: Ovarian cancer is the leading cause of death among gynecological cancers, but is poorly amenable to preoperative diagnosis. In this study, we investigate the feasibility of “optical biopsy,” using high-optical-resolution photoacoustic microscopy (OR-PAM) to quantify the microvasculature of ovarian and fallopian tube tissue. The technique is demonstrated using excised human ovary and fallopian tube specimens imaged immediately after surgery. Quantitative parameters are derived using Amira software. The parameters include three-dimensional vascular segment count, total volume and length, which are associated with tumor angiogenesis. Qualitative results of OR-PAM demonstrate that malignant ovarian tissue has larger and more tortuous blood vessels as well as smaller vessels of different sizes, while benign and normal ovarian tissue has smaller vessels of uniform size. Quantitative analysis shows that malignant ovaries have greater tumor vessel volume, length and number of segments, as compared with benign and normal ovaries. The vascular pattern of benign fallopian tube is different than that of benign ovarian tissue. Our initial results demonstrate the potential of OR-PAM as an imaging tool for fast assessment of ovarian tissue and fallopian tube and could avoid unnecessary surgery if the risk of the examined ovary is extremely low.
    Electronic ISSN: 2045-2322
    Topics: Natural Sciences in General
    Published by Springer Nature
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  • 2
    Electronic Resource
    Electronic Resource
    New York, NY : Wiley-Blackwell
    Helvetica Chimica Acta 71 (1988), S. 992-999 
    ISSN: 0018-019X
    Keywords: Chemistry ; Organic Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Notes: The vibrational spectra of some 1,2,4-trioxanes present two characteristic bands at 790 and 880 cm-1. On the basis of 18O-isotopic substitution and comparison with analogous compounds, these bands have been assigned to coupled C—O and O—O stretching modes of the C—O—O element.
    Additional Material: 5 Ill.
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  • 3
    Electronic Resource
    Electronic Resource
    Weinheim : Wiley-Blackwell
    Materialwissenschaft und Werkstofftechnik 28 (1997), S. 287-292 
    ISSN: 0933-5137
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Description / Table of Contents: Investigations of initiation of intercrystalline fatigue cracks of interstitial free (IF-) steelsWhile investigation the fatigue strength of interstitial free steels, intercrystalline fatigue cracks have occurred as a damage which could reduce the application range of this material, being wellknown for its excellent depth drawing features. Through metallographic examination the known causes of the damage like formation of grain cover tertiary zementit of precipitations on the grain boundaries could be excluded. In this paper investigation results are represented which are received through high-resolution analyses techniques (TEM, AES).
    Notes: Bei Untersuchungen zur Ermüdungsfestigkeit interstitiell freier Stähle sind mit dem Auftreten interkristalliner Schwingungsrisse erstmals Schadensmechanismen aufgetreten, die den Einsatzbereich dieses für seine hervorragenden mechanischen Eigenschaften bekannten Werkstoffes erheblich begrenzen können. In metallographischen Untersuchungen konnten die für dieses Schadensbild bekannten Ursachen wie die Bildung von schalenförmigem Tertiärzementit oder die Schwächung der Korngrenzen durch Ausscheidungen ausgeschlossen werden. Im vorliegenden Beitrag werden Untersuchungsergebnisse mit hochauflösenden elektronenoptischen Analyseverfahren (TEN, AES) vorgestellt.
    Additional Material: 8 Ill.
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  • 4
    ISSN: 0003-3146
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology , Physics
    Description / Table of Contents: Homopolymers of 2-, 3- and 4-trifluoromethylstyrene, 4-perfluoroisopropylstyrene, 3,5-bis-trifluoromethyl-styrene and a 1 : 1 copolymer of 2,4- and 2,5-bis-trifluoromethyl-styrene have been synthesized and the refractive indices nD, Abbe-numbers νD and glass transition temperatures of the polymers have been determined.With regard to optical applications poly-2-trifluoromethyl-styrene is particularly interesting since its optical properties are in a region of the n-ν-diagram that has not been reached by thermoplastic polymers or inorganic glasses before.The most important mechanical and thermal properties of this polymer are reported. Reactivity ratios of the binary copolymerisation of 2-trifluoromethyl-styrene with styrene, methyl-methacrylate and n-butyl-acrylate are listed as well as optical data and glass transition temperatures of some copolymers of 2-trifluoromethyl-styrene.
    Notes: Homopolymerisate aus 2-, 3- und 4-Trifluormethylstyrol, 4-Perfluorisopropylstyrol, 3,5-Bis-trifluormethylstyrol und ein 1 : 1 Copolymerisat aus 2,4- und 2,5-Bis-trifluormethylstyrol wurden hergestellt und Brechungsindices, Abbe-Zahlen sowie Glasübergangstemperaturen der Polymerisate bestimmt.Von diesen Thermoplasten ist das Poly-2-trifluormethylstyrol im Hinblick auf optische Anwendungen besonders interessant, da es in einem weder von anorganischen Gläsern noch von bekannten thermoplastischen Kunststoffen bisher erreichten Gebiet des n-v-Diagrammes liegt.Die wichtigsten mechanischen und thermischen Eigenschaften dieses Polymeren und die Copolymerisationsparameter für die binäre Copolymerisation von 2-Trifluormethylstyrol mit Styrol, Methylmethacrylat und n-Butylacrylat wurden bestimmt. Optische Daten und Glastemperaturen einiger Copolymerisate des 2-Trifluormethylstyrols werden mitgeteilt.
    Additional Material: 2 Ill.
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  • 5
    Electronic Resource
    Electronic Resource
    New York, N.Y. : Wiley-Blackwell
    Journal of Cellular Biochemistry 68 (1998), S. 259-268 
    ISSN: 0730-2312
    Keywords: multifunctional Ca2+/calmodulin-dependent protein kinase ; cardiac isoforms ; muscle differentiation ; cell line Hgc2 ; adult rat heart ; Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Chemistry and Pharmacology , Medicine
    Notes: Despite their important role in controlling the cardiac Ca2+ homeostasis, presence and functions of individual isoforms of the multifunctional Ca2+/calmodulin-dependent protein kinase in the heart are not well studied. Here we report on expression of isoforms of the δ class in two differentiation states of the embryonic rat heart-derived cell line H9c2 compared to adult rat heart. Reverse transcription coupled polymerase chain reaction analysis revealed specific expression patterns of four variants of the δ class (δB, δC, δ4, δ9) in adult rat heart, H9c2 myoblasts, and skeletal muscle-like H9c2 myotubes. δC was identified as a common isoform with higher amounts in H9c2 cells and the prominent one in myoblasts. In contrast, expression of δ9 accompanied cardiac as well as skeletal muscle differentiation. Expression of δB, however, was representative for differentiated cardiac muscle, whereas δ4 expression coincided with differentiation into the skeletal muscle-like state. Our results demonstrate differentiation-dependent isoform expression of the δ class of the multifunctional Ca2+/calmodulin-dependent protein kinase of muscle. The identification of cardiac target proteins for this kinase, e.g. the α1-subunit of the L-type Ca2+ channel, the sarcoplasmic reticulum Ca2+-ATPase, phospholamban and the ryanodine receptor define H9c2 myoblasts as a suitable model system for further functional characterization of the identified cardiac δ isoforms. J. Cell. Biochem. 68:259-268, 1998. © 1998 Wiley-Liss, Inc.
    Additional Material: 4 Ill.
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  • 6
    Electronic Resource
    Electronic Resource
    New York, NY : Wiley-Blackwell
    Gamete Research 22 (1989), S. 233-247 
    ISSN: 0148-7280
    Keywords: chimera ; transgenics ; embryos ; ES cells ; Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology
    Notes: The preimplantation embryo is highly resilient to experimental manipulations. A specific manipulation that has revealed many clues to the developmental process is chimera production. Chimeras have been used to describe the importance of developmental characteristics of embryonic cells and how these characteristics are involved with developmental fate. These characteristics have been monopolized in the production of interspecific chimeras and the production of transgenic animals. This review attempts to discuss the major factors affecting preimplantation mammalian embryo chimera production.
    Type of Medium: Electronic Resource
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  • 7
    Electronic Resource
    Electronic Resource
    Chichester : Wiley-Blackwell
    Biological Mass Spectrometry 10 (1983), S. 559-566 
    ISSN: 0306-042X
    Keywords: Chemistry ; Analytical Chemistry and Spectroscopy
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Notes: The positive ion and negative ion pyrolysis mass spectra of the herring sperm DNA have been studied using desorption chemical ionization. The positive ion desorption chemical ionization spectra have been produced with CH4, i-C4H10, NH3, HCl and Cl2; the negative ones with N2O/CH4, N2O/i-C4H10, Cl2, CCl4, HCI and via electron capture. These spectra have been compared with the electron impact ionization spectra. We have observed an important increase of sensitivity when negative ionization has replaced the positive ionization mode. The series of diagnostic ions resulting from direct chemical ionization belong to the family of base + reagent ion X [BH + X] and base + X-HX ion [B]. Their abundance has increased considerably compared to the electron impact spectra. The application of these new diagnostic ions in nucleic acid studies is interesting especially for the much higher abundance of the usually weak dG fragment ion obtained in the negative ionization mode. The dG-base segment of the DNA is the most nucleophilic centre of the whole nucleic acid and is implicated in numerous important biochemical reactions involving, for example, proteins.
    Additional Material: 13 Ill.
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  • 8
    Electronic Resource
    Electronic Resource
    Weinheim : Wiley-Blackwell
    Zeitschrift für die chemische Industrie 93 (1981), S. 813-814 
    ISSN: 0044-8249
    Keywords: Chemistry ; General Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
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  • 9
    Electronic Resource
    Electronic Resource
    Weinheim : Wiley-Blackwell
    Zeitschrift für anorganische Chemie 622 (1996), S. 1374-1380 
    ISSN: 0044-2313
    Keywords: Mixed barium halides ; crystal growth ; X-ray diffraction ; Raman spectroscopy ; Chemistry ; Inorganic Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Description / Table of Contents: Synthese und Struktur von Ba12F19ClδBr5-δ-MischkristallenIn der Struktur Ba12F19Cl5 [hexagonale Raumgruppe P62m] kann Chlorid auf den Positionen Cl(1) und Cl(2) teilweise durch Bromidionen ersetzt werden. Einkristalle des Typs Ba12F19ClδBr5-δ mit einem Chlorid zu Bromid Verhältnis von maximal 2 : 3 wurden aus einer Schmelze von 75 mol% BaF2 und 25 mol% BaX2 (X = Cl, Br) erhalten. Die Kristallqualität nimmt mit zunehmendem Bromidgehalt ab. Strukturdaten von fünf ausgewählten Einkristallen mit unterschiedlichem Chlorid zu Bromid Verhältnis wurden mit Hilfe von Röntgen-Einkristallbeugungsmethoden bestimmt. Die verfeinerten Besetzungswerte der Halogene stimmen gut mit dem Cl zu Br Verhältnis der Schmelze überein. Die Gitterparameter und interatomaren Abstände ändern sich, wenn Cl- durch das größere Br- ersetzt wird. Die Verfeinerungen zeigen eine statistische Verteilung der Halogene auf beiden Gitterplätzen, wobei allerdings Cl- auf der Position Cl(1) bevorzugt durch Br- ersetzt wird.
    Notes: In the structure Ba12F19Cl5 [hexagonal space group P62m] the two chlorides on the sites Cl(1) and Cl(2) can partially be replaced by bromide ions. Single crystals of the type Ba12F19ClδBr5-δ with a chloride to bromide ratio up to 2 : 3 could be obtained by cooling a flux of 75 mol% BaF2 and 25 mol% BaX2 with X = Cl, Br. The crystal quality decreases with increasing bromide concentration. Structural parameters of five selected single crystals with different chloride/bromide ratio were studied by single crystal X-ray diffraction methods. The refined total Cl-/Br- population ratio in the crystals is close to the one of the flux. The lattice parameters and interatomic distances change in various ways, when the smaller chloride ion is replaced by the bigger bromide ion. The refinements show a statistical disorder on the halide sites with preferential bromide substitution on site Cl(1).
    Additional Material: 9 Ill.
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  • 10
    Electronic Resource
    Electronic Resource
    Weinheim : Wiley-Blackwell
    Zeitschrift für anorganische Chemie 623 (1997), S. 573-578 
    ISSN: 0044-2313
    Keywords: Barium magnesium fluorides ; X-ray crystallography, Raman spectroscopy ; Chemistry ; Inorganic Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Description / Table of Contents: Synthese und Struktur von Ba6Mg7F26Eine neue Verbindung des binären Phasendiagramms von BaF2 und MgF2 wurde synthetisiert. Nach Czrochalsky-Kristallzucht von BaMgF4 wurden nadelförmige Kristalle an der Oberfläche der verbleibenden Schmelze gefunden. Ba6Mg7F26 kristallisiert in der orthorhombischen Raumgruppe Immm mit den Gitterparametern von a = 585.35(4), b = 1214.95(7) und c = 1511.09(9) pm.Die Struktur wird aufgebaut von perowskit- und rutilähnlichen Bausteinen. Alle Mg2+ haben eine oktaedrische Umgebung von F mit minimalen (maximalen) Bindungslängen von 192,1(2) (227.4(3)) pm.Ba1 und Ba2 haben verschiedene Koordinationspolyeder mit den Koordinationszahlen (CN) von 12 + 1 und 12. Die verschiedenen Anionen haben CN von 6, 4 bzw. 3 zu den benachbarten Metallatomen.Vorläufige Raman Messungen zeigen deutliche Unterschiede zwischen den Spektren von BaMgF4 und Ba6Mg7F26.
    Notes: A new compound in the binary phase diagram of BaF2 and MgF2 was synthesized. After Czrochalsky growth of BaMgF4, needle shaped crystals were found on the surface of the cooled residual mass. The compound Ba6Mg7F26 crystallizes in the orthorhombic space group Immm with lattice parameters of a = 585.35(4), b = 1214.95(7), and c = 1511.09(9) pm.The global structure can be described as build up of perovskite like blocks and rutile related parts. Magnesium ions have an octahedral fluoride environment with minimum (maximum) bond distances of 192.1(2) (227.4(3)) pm.Two different barium environments with coordination number (C.N.) of 12 + 1 (Ba1) and 12 (Ba2) were found. The different fluoride ions can have C.N. of 6, 4 or 3 with the nearest metal atoms.Preliminary Raman spectra show significant differences between BaMgF4 and Ba6Mg7F26.
    Additional Material: 5 Ill.
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