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  • Wiley  (34)
  • American Society of Hematology  (8)
  • Oxford University Press  (5)
  • Heidelberg: Springer
  • Nature Publishing Group
  • 2015-2019  (33)
  • 2000-2004  (14)
  • 1975-1979  (2)
  • 1925-1929  (2)
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  • 1
    Publication Date: 2000-11-01
    Print ISSN: 0024-3590
    Electronic ISSN: 1939-5590
    Topics: Biology , Geosciences , Physics
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  • 2
    Electronic Resource
    Electronic Resource
    [s.l.] : Nature Publishing Group
    Nature 278 (1979), S. 551-553 
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] The ABC-1 cells are large, vacuolated, undifferentiated blast cells. Immunofluorescence and cytotoxicity tests indicated that no cells had cell surface immunoglobulin (Smlg) or expressed detectable levels of Thy-1.2, suggesting that there were no mature B or T lymphocytes present. Additional ...
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  • 3
    Electronic Resource
    Electronic Resource
    [s.l.] : Nature Publishing Group
    Nature 416 (2002), S. 847-850 
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] The transition from vegetative to reproductive growth is an essential process in the life cycle of plants. Plant floral induction pathways respond to both environmental and endogenous cues and much has been learnt about these genetic pathways by studying mutants of Arabidopsis. ...
    Type of Medium: Electronic Resource
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  • 4
    Electronic Resource
    Electronic Resource
    [s.l.] : Nature Publishing Group
    Nature 409 (2001), S. 462-463 
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] Planet hunters keep discovering yet more weird objects around nearby Sun-like stars that resemble nothing found in our own Solar System. The latest discoveries, announced at a meeting earlier this month*, include a three-body system that appears to be composed of a central star orbited by ...
    Type of Medium: Electronic Resource
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  • 5
    Electronic Resource
    Electronic Resource
    [s.l.] : Nature Publishing Group
    Nature 432 (2004), S. 957-958 
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] The meteorites and comets that were formed in the solar nebula, the planet-forming disk of gas and dust that became our Solar System, have been largely unaltered over time, and their structure provides clues about the physical and chemical processes that occurred in the nebula. One group of early ...
    Type of Medium: Electronic Resource
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  • 6
    Publication Date: 2019
    Description: Abstract Two Bio‐Argo floats measured the concentration of chlorophyll‐a, the backscattering coefficient, the fluorescence of humic‐like dissolved organic matter, dissolved oxygen, and temperature and salinity in the northern and central basins of the South China Sea for over 2 years. Temporal evolutions of bio‐optical properties were analyzed at surface, subsurface, and in the whole water column, respectively. It was found that (1) The seasonal variability of the surface chlorophyll‐a was highly controlled by photoacclimation, especially in the central basin; (2) backscattering in the upper 150 m was nearly constant, exhibiting no distinct seasonality; (3) with vertical mixing, particles from the deep chlorophyll maxima were entrained into the mixed layer resulting in enhanced surface chlorophyll during the early winter. This phenomenon may mislead a study based on satellite data which is likely to interpret it as blooming rather than a redistribution of phytoplankton within the water column; (4) analysis of a winter bloom and an anticyclonic eddy reveal that physical entrainment and biological photoacclimation modulated the vertical distributions of chlorophyll‐a and particles and potentially also changes of phytoplankton community composition; and (5) fluorescent dissolved organic matter was found to be highly coupled to phytoplankton dynamics in both basins, with a maximum (after removing the contribution of physical convective mixing) located at the depth of chlorophyll‐a subsurface maximum.
    Print ISSN: 2169-9275
    Electronic ISSN: 2169-9291
    Topics: Geosciences , Physics
    Published by Wiley on behalf of American Geophysical Union (AGU).
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  • 7
    Publication Date: 2015-04-02
    Description: The class II transactivator (CIITA) is essential for the expression of major histocompatibility complex class II (MHC-II) genes; however, the role of CIITA in gene regulation outside of MHC-II biology is not fully understood. To comprehensively map CIITA-bound loci, ChIP-seq was performed in the human B lymphoblastoma cell line Raji. CIITA bound 480 sites, and was significantly enriched at active promoters and enhancers. The complexity of CIITA transcriptional regulation of target genes was analyzed using a combination of CIITA -null cells, including a novel cell line created using CRISPR/Cas9 tools. MHC-II genes and a few novel genes were regulated by CIITA; however, most other genes demonstrated either diminished or no changes in the absence of CIITA. Nearly all CIITA-bound sites were within regions containing accessible chromatin, and CIITA's presence at these sites was associated with increased histone H3K27 acetylation, suggesting that CIITA's role at these non-regulated loci may be to poise the region for subsequent regulation. Computational genome-wide modeling of the CIITA bound XY box motifs provided constraints for sequences associated with CIITA-mediated gene regulation versus binding. These data therefore define the CIITA regulome in B cells and establish sequence specificities that predict activity for an essential regulator of the adaptive immune response.
    Print ISSN: 0305-1048
    Electronic ISSN: 1362-4962
    Topics: Biology
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  • 8
    Publication Date: 2019
    Description: Abstract Biogeochemical Argo floats, profiling to 2,000‐m depth, are being deployed throughout the Southern Ocean by the Southern Ocean Carbon and Climate Observations and Modeling program (SOCCOM). The goal is 200 floats by 2020, to provide the first full set of annual cycles of carbon, oxygen, nitrate, and optical properties across multiple oceanographic regimes. Building from no prior coverage to a sparse array, deployments are based on prior knowledge of water mass properties, mean frontal locations, mean circulation and eddy variability, winds, air‐sea heat/freshwater/carbon exchange, prior Argo trajectories, and float simulations in the Southern Ocean State Estimate and Hybrid Coordinate Ocean Model (HYCOM). Twelve floats deployed from the 2014–2015 Polarstern cruise from South Africa to Antarctica are used as a test case to evaluate the deployment strategy adopted for SOCCOM's 20 deployment cruises and 126 floats to date. After several years, these floats continue to represent the deployment zones targeted in advance: (1) Weddell Gyre sea ice zone, observing the Antarctic Slope Front, and a decadally‐rare polynya over Maud Rise; (2) Antarctic Circumpolar Current (ACC) including the topographically steered Southern Zone chimney where upwelling carbon/nutrient‐rich deep waters produce surprisingly large carbon dioxide outgassing; (3) Subantarctic and Subtropical zones between the ACC and Africa; and (4) Cape Basin. Argo floats and eddy‐resolving HYCOM simulations were the best predictors of individual SOCCOM float pathways, with uncertainty after 2 years of order 1,000 km in the sea ice zone and more than double that in and north of the ACC.
    Print ISSN: 2169-9275
    Electronic ISSN: 2169-9291
    Topics: Geosciences , Physics
    Published by Wiley on behalf of American Geophysical Union (AGU).
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  • 9
    Publication Date: 2017-08-10
    Description: Phytoplankton blooms are elements in repeating annual cycles of phytoplankton biomass and they have significant ecological and biogeochemical consequences. Temporal changes in phytoplankton biomass are governed by complex predator-prey interactions and physically-driven variations in upper water-column the growth conditions (light, nutrient, temperature). Understanding these dependencies is fundamental to assessing future change in bloom frequency, duration, and magnitude and thus represents a quintessential challenge in global change biology. A variety of contrasting hypotheses have emerged in the literature to explain phytoplankton blooms, but over time the basic tenets of these hypotheses have become unclear. Here, we provide a ‘tutorial’ on the development of these concepts and the fundamental elements distinguishing each hypothesis. The intent of this tutorial is to provide a useful background and set of tools for reading the bloom literature and to give some suggestions for future studies. Our tutorial is written for ‘students’ at all stages of their career. We hope it is equally useful and interesting to those with only a cursory interest in blooms as those deeply immersed in the challenge of understanding the temporal dynamics of phytoplankton biomass and predicting its future change. This article is protected by copyright. All rights reserved.
    Print ISSN: 1354-1013
    Electronic ISSN: 1365-2486
    Topics: Biology , Energy, Environment Protection, Nuclear Power Engineering , Geography
    Published by Wiley
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  • 10
    Publication Date: 2017-11-22
    Description: Phytoplankton community composition in the ocean is complex and highly variable over a wide range of space and time scales. Able to cover these scales, remote-sensing reflectance spectra can be measured both by satellite and by in situ radiometers. The spectral shape of reflectance in the open ocean is influenced by the particles in the water, mainly phytoplankton and co-varying non-algal particles. We investigate the utility of in situ hyperspectral remote-sensing reflectance measurements to detect phytoplankton pigments by using an inversion algorithm that defines phytoplankton pigment absorption as a sum of Gaussian functions. The inverted amplitudes of the Gaussian functions representing pigment absorption are compared to coincident High Performance Liquid Chromatography measurements of pigment concentration. We determined strong predictive capability for chlorophylls a, b, c 1 + c 2 , and the photoprotective carotenoids. We also tested the estimation of pigment concentrations from reflectance-derived chlorophyll a using global relationships of co-variation between chlorophyll a and the accessory pigments. We found similar errors in pigment estimation based on the relationships of co-variation versus the inversion algorithm. An investigation of spectral residuals in reflectance data after removal of chlorophyll-based average absorption spectra showed no strong relationship between spectral residuals and pigments. Ultimately, we are able to estimate concentrations of three chlorophylls and the photoprotective carotenoid pigments, noting that further work is necessary to address the challenge of extracting information from hyperspectral reflectance beyond the information that can be determined from chlorophyll a and its co-variation with other pigments.
    Print ISSN: 0148-0227
    Topics: Geosciences , Physics
    Published by Wiley on behalf of American Geophysical Union (AGU).
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