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  • *Cell Transformation, Viral  (2)
  • *Disasters  (1)
  • American Association for the Advancement of Science (AAAS)  (3)
  • Geological Society of America (GSA)
  • Periodicals Archive Online (PAO)
  • 2015-2019  (1)
  • 2000-2004
  • 1995-1999
  • 1980-1984  (2)
  • 1950-1954
Collection
Publisher
  • American Association for the Advancement of Science (AAAS)  (3)
  • Geological Society of America (GSA)
  • Periodicals Archive Online (PAO)
Years
  • 2015-2019  (1)
  • 2000-2004
  • 1995-1999
  • 1980-1984  (2)
  • 1950-1954
Year
  • 1
    Publication Date: 2015-08-22
    Description: Although disturbances such as fire and native insects can contribute to natural dynamics of forest health, exceptional droughts, directly and in combination with other disturbance factors, are pushing some temperate forests beyond thresholds of sustainability. Interactions from increasing temperatures, drought, native insects and pathogens, and uncharacteristically severe wildfire are resulting in forest mortality beyond the levels of 20th-century experience. Additional anthropogenic stressors, such as atmospheric pollution and invasive species, further weaken trees in some regions. Although continuing climate change will likely drive many areas of temperate forest toward large-scale transformations, management actions can help ease transitions and minimize losses of socially valued ecosystem services.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Millar, Constance I -- Stephenson, Nathan L -- New York, N.Y. -- Science. 2015 Aug 21;349(6250):823-6. doi: 10.1126/science.aaa9933.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉U.S. Department of Agriculture Forest Service, Pacific Southwest Research Station, Albany, CA 94710, USA. cmillar@fs.fed.us. ; U.S. Geological Survey, Western Ecological Research Center, Three Rivers, CA 93271, USA.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/26293954" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; *Climate Change ; *Disasters ; Droughts ; Environmental Restoration and Remediation ; Fires ; *Forests ; Insects ; *Trees
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 2
    Publication Date: 1982-05-21
    Description: Rat embryo fibroblasts transformed by Abelson murine leukemia virus (MuLV) produce and release a transforming growth factor (TGF). Production of this factor is correlated with a tyrosine-specific protein kinase that is functionally active and is associated with the major Abelson MuLV gene product, P120. Transformation-defective mutants of Abelson MuLV do not transform cells, do not have their virus coded transforming gene product phosphorylated in tyrosine, and do not induce TGF production. Abelson MuLV-induced TGF morphologically transforms cells in culture, competes with 125I-labeled epidermal growth factor (EGF) for binding to cell receptors, and induces phosphorylation of tyrosine acceptor sites in the 160,000-dalton EGF membrane receptor. After purification to homogeneity, Abelson virus-induced TGF migrates as a single polypeptide with an apparent size of 7400 daltons as determined by sodium dodecyl sulfate-polyacrylamide gel electrophoresis.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Twardzik, D R -- Todaro, G J -- Marquardt, H -- Reynolds, F H Jr -- Stephenson, J R -- New York, N.Y. -- Science. 1982 May 21;216(4548):894-7.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/6177040" target="_blank"〉PubMed〈/a〉
    Keywords: Abelson murine leukemia virus ; Animals ; *Cell Transformation, Neoplastic ; *Cell Transformation, Viral ; Molecular Weight ; Peptides/*metabolism ; Phosphotyrosine ; Rats ; Receptor, Epidermal Growth Factor ; Receptors, Cell Surface/metabolism ; Transforming Growth Factors ; Tyrosine/analogs & derivatives/metabolism
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 3
    Publication Date: 1982-06-04
    Description: To define the human homolog (or homologs) of transforming sequences (v-fes gene) common to Gardner (GA) and Snyder Theilen (ST) isolates of feline sarcoma virus (FeSV), a representative library of human lung carcinoma DNA in a cosmid vector system was constructed. Three cosmid clones were isolated containing GA/ST FeSV v-fes homologous cellular sequences, within 32- to 42-kilobase cellular inserts representing 56 kilobases of contiguous human cellular DNA. Sequences both homologous to, and colinear with, GA or ST FeSV v-fes are distributed discontinuously over a region of up to 9.5 kilobases and contain a minimum of three regions of nonhomology representing probable introns. A thymidine kinase selection system was used to show that, upon transfection to RAT-2 cells, the human c-fes sequence lacked detectable transforming activity.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Groffen, J -- Heisterkamp, N -- Grosveld, F -- Van de Ven, W -- Stephenson, J R -- N0I-CO-75380/CO/NCI NIH HHS/ -- New York, N.Y. -- Science. 1982 Jun 4;216(4550):1136-8.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/6281890" target="_blank"〉PubMed〈/a〉
    Keywords: Bacteriophage lambda/genetics ; *Cell Transformation, Viral ; Cloning, Molecular/methods ; DNA Restriction Enzymes ; DNA, Recombinant ; Escherichia coli/genetics ; *Genes, Viral ; Humans ; Retroviridae/*genetics
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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