Publikationsdatum:
2011-07-27
Beschreibung:
Goldfeld et al. (1) presented modeling results on restoring 3D structures of the intra- and extracellular loops in bovine rhodopsin (bRh), human A2A adenosine receptor (A2Ar), turkey β1-adrenergic receptor (β1AR), and human β2-adrenergic receptor (β2AR). In all cases, the lowest energy conformers of the loops matched the corresponding X-ray structures with excellent rmsd values. The extracellular loops for the same receptors were modeled in our article previously (2) with the use of a much less sophisticated modeling procedure. Goldfeld et al. (1) emphasized substantially better accuracy of reproducing the X-ray structures of the loops, especially larger loops, in their study...
Schlagwort(e):
Letters
Print ISSN:
0027-8424
Digitale ISSN:
1091-6490
Thema:
Biologie
,
Medizin
,
Allgemeine Naturwissenschaft
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