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  • 1
    Publikationsdatum: 2024-04-20
    Beschreibung: Accurate long-term temperature and precipitation estimates at high spatial and temporal resolutions are vital for a wide variety of climatological studies. We have produced a new, publicly available, daily, gridded maximum temperature, minimum temperature, and precipitation dataset for China with a high spatial resolution of 1 km and over a long-term period (1961 to 2019). It has been named the HRLT. The daily gridded data were interpolated using comprehensive statistical analyses, which included machine learning, the generalized additive model, and thin plate splines. It is based on the 0.5° × 0.5° grid dataset from the China Meteorological Administration, together with covariates for elevation, aspect, slope, topographic wetness index, latitude, and longitude. The accuracy of the HRLT daily dataset was assessed using meteorological station observation data. The maximum and minimum temperature estimates were more accurate than the precipitation estimates. For maximum temperature, the mean absolute error (MAE), root mean square error (RMSE), Pearson's correlation coefficient (Cor), coefficient of determination after adjustment (R^2), and Nash-Sutcliffe modeling efficiency (NSE) were 1.07 ℃, 1.62 ℃, 0.99, 0.98, and 0.98, respectively. For minimum temperature, the MAE, RMSE, Cor, R^2, and NSE were 1.08 ℃, 1.53 ℃, 0.99, 0.99, and 0.99, respectively. For precipitation, the MAE, RMSE, Cor, R^2, and NSE were 1.30 mm, 4.78 mm, 0.84, 0.71, and 0.70, respectively. The accuracy of the HRLT was compared to those of the other two existing datasets and its accuracy was either greater than the others, especially for precipitation, or comparable in accuracy, but with higher spatial resolution and over a longer time period. In summary, the HRLT dataset, which has a high spatial resolution, covers a longer period of time and has reliable accuracy, is suitable for future environmental analyses, especially the effects of extreme weather.
    Schlagwort(e): Binary Object; Binary Object (File Size); Binary Object (Media Type); China; precipitation; Temperature
    Materialart: Dataset
    Format: text/tab-separated-values, 177 data points
    Standort Signatur Erwartet Verfügbarkeit
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  • 2
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    Springer Nature
    Publikationsdatum: 2024-04-05
    Beschreibung: Innovations in molecular biology are allowing neuroscientists to study the brain with unprecedented resolution, from the level of single molecules to integrated gene circuits. Chief among these innovations is the CRISPR-Cas genome editing technology, which has the precision and scalability to tackle the complexity of the brain. This Colloque Médecine et Recherche has brought together experts from around the world that are applying genome editing to address important challenges in neuroscience, including basic biology in model organisms that has the power to reveal systems-level insight into how the nervous system develops and functions as well as research focused on understanding and treating human neurological disorders.
    Schlagwort(e): RC321-571 ; QH426-470 ; CRISPR ; muscular dystrophy ; Parkinson's disease ; DNA ; Rett syndrome ; double-strand breaks ; Huntington's disease ; genetic engineering ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSA Life sciences: general issues::PSAN Neurosciences
    Sprache: Englisch
    Format: image/jpeg
    Standort Signatur Erwartet Verfügbarkeit
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