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  • Biotechnology.  (4)
  • Cham :Springer International Publishing :  (4)
  • American Chemical Society (ACS)
  • American Meteorological Society
  • 2020-2024  (4)
  • 1975-1979
  • 1935-1939
Collection
Publisher
Language
Years
  • 2020-2024  (4)
  • 1975-1979
  • 1935-1939
Year
  • 1
    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Microbiology. ; Environmental engineering. ; Biotechnology. ; Bioremediation. ; Microbial ecology. ; Industrial microbiology. ; Microbiology. ; Environmental Engineering/Biotechnology. ; Microbial Ecology. ; Industrial Microbiology.
    Description / Table of Contents: 1. Sulfate-reducing prokaryotes: Changing paradigms -- 2. Characteristics and taxonomy -- 3. Reduction of sulfur and nitrogen compounds -- 4. Electron transport proteins and cytochromes -- 5. Systems contributing to the energetics of SRP -- 6. Cell biology and metabolism -- 7. Geomicrobiology, biotechnology, and industrial applications -- 8. Biocorrosion -- 9. Ecology of dissimilatory sulfate reducers: Life in extreme conditions and activities of SRB -- 10. Interactions of SRB with animals and plants.
    Abstract: The abundance of sulfate-reducing bacteria and archaea (SRBA) is impressive and new isolates are being reported continuously. A few decades ago, only two genera of dissimilatory sulfate reducers had been identified and as of 2018, 92 genera containing more than 420 species of SRB and several species of archaea have been isolated. This book addresses the historical background of SRBA research and reviews the current status of research examining the growth of these anaerobic microorganisms. Additionally, this book covers metabolic and genomic diversity, enzymatic processes, response to stress, biocorrosion of ferrous metals, biogeochemical processes and interactions with other microorganisms in the anaerobic biosphere. It highlights the unique cellular and molecular features of these microorganisms, discusses the production and consumption of gases and reviews genomic content influencing their metabolic capabilities. Examples are provided of detoxification reactions to alleviate pollution situations, growth in in hostile environments including low nutrient availability, and the effects of sulfate-reducing bacteria (SRB) on human and animal hosts.
    Type of Medium: Online Resource
    Pages: XI, 564 p. 62 illus., 38 illus. in color. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783030967031
    DDC: 579
    Language: English
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  • 2
    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Pharmacology. ; Pharmacovigilance. ; Pharmaceutical chemistry. ; Chemistry, Physical and theoretical. ; Biotechnology. ; Pharmacology. ; Drug Safety and Pharmacovigilance. ; Pharmaceutics. ; Theoretical Chemistry. ; Biotechnology.
    Description / Table of Contents: Introduction -- PART 1: How Drugs are Discovered and Developed in the Pharmaceutical Industry -- Introduction to Drugs and Drug Targets -- Background to chemistry of small and large molecules -- Laying the foundations- Drug discovery from antiquity to the twenty first century -- Part II-The drug development pipeline – discovery to testing in humans -- Drug discovery pipeline overview -- Target discovery -- Medicinal chemistry -- Biotherapeutics -- Screening for hits -- Process chemistry and formulation -- Preclinical development -- Part III-The drug development pipeline – clinical trials to marketing authorisation -- Clinical trials -- Regulatory affairs and marketing approval -- Diagnostics and personalized medicine -- Putting it All Together: a drug development case history -- Part IV- The Global Pharmaceuticals Business -- Commercial aspects of drug development -- Challenges and responses -- Part V - Professional Interactions with the Drug Discovery Industry.-Professional Interactions with the Drug Discovery Industry: Technology Transfer Executives -- Recruitment Executives -- Pharmaceutical translators and Interpreters.
    Abstract: The Science and Business of Drug Discovery is written for those who want to learn about the biopharmaceutical industry and its products whatever their level of technical knowledge. Its aim is to demystify the jargon used in drug development, but in a way that avoids over simplification and the resulting loss of key information. Each of the twenty chapters is illustrated with figures and tables which clarify some of the more technical points being made. Also included is a drug discovery case history which draws the relevant material together into a single chapter. In recognizing that it is difficult to navigate through the many external resources dealing with drug development, the book has been written to guide the reader towards the most appropriate information sources, including those listed in the two appendices. The following topics are covered: Different types of drugs: from small molecules to stem cells Background to chemistry of small and large molecules Historical background to drug discovery, pharmacology and biotechnology The drug discovery pipeline: from target discovery to marketed medicine Commercial aspects of drug discovery Challenges to the biopharmaceutical industry and its responses Material of specific interest to technology transfer executives, recruiters and pharmaceutical translators .
    Type of Medium: Online Resource
    Pages: XVII, 402 p. 102 illus., 20 illus. in color. , online resource.
    Edition: 2nd ed. 2020.
    ISBN: 9783030578145
    DDC: 615
    Language: English
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  • 3
    Keywords: Nanotechnology. ; Biomaterials. ; Biology Technique. ; Agriculture. ; Biotechnology. ; Molecular biology. ; Nanotechnology. ; Plant Materials. ; Biological Techniques. ; Agriculture. ; Biotechnology. ; Molecular Biology.
    Description / Table of Contents: Preface -- 1. Nano-Biofortification: Finding an Alternative Approach -- 2. Soil ecosystem services and environmental health -- 3. Malnutrition and human health -- 4. Nano-Biofortification: an environmental health overview -- 5. Phytomedicine and medicinal plants -- 6. Role of phytomedicines and medicinal plants in bacterial and viral diseases -- 7. Plant-based diets and cardiovascular health -- 8. Nano-Biofortified crop plants with selenium for human health -- 9. Biofortified crop plants with iodine for human health -- 10. Nano-Biofortified crop plants with copper for human health -- 11. Nano-Biofortified crop plants with zinc for human health -- 12. Nano-Biofortified crop plants with iron for human health -- 13. Plant leaf protein concentrate for human health -- 14. Plant secondary metabolites and human health -- 15. Plant nano-remediation and human health -- 16. Plant nano-nutrition management for human health -- 17. Physiological functions of plant nano-nutrients in human health -- 18. Nanofertilizers in Agriculture -- 19. Biofortification to Improve Micronutrient-Dense Plants -- 20. Nano-Biofortification of vegetables for nutritive values and qualitative traits -- Bibliography -- Index.
    Abstract: Nanotechnology has shown great potential to alleviate increasing pressure to meet food needs for our increasing human population, Novel agricultural innovations are required to enhance the health of edible crops and per unit area yield without impacting the associated environment in a negative way. Recent advancements in nanotechnology-based agricultural solutions have proven to help overcome the problems in agriculture that are associated with run-off of essential fertilizers from agricultural soils, low nutrient accumulation by crops, as well as to control insects, pests, and seasonal biotic factors, treatment of wastewater used for irrigation, plant uptake of xenobiotics (heavy metals, pesticides, industrial chemicals, drugs, and so on) that may be present in contaminated soils. Additionally, the consumption of such food crops may result in malnourishment and plant-mediated transfer of toxic substances among humans especially in underprivileged and rural populations. Agents to stimulate plant growth include various types of nanomaterials such as carbon nanotubes, metal, and metal-oxide nanoparticles. Applications of particular nutrients or elements in crop plants can be shown to aid human nourishment (either by directly inducing its uptake or indirectly through enhancing the intracellular levels of other associated elements that ultimately boost the synthesis of the desired nutrient in plants). It is also important to consider the competence and fate of nanomaterials in soil ecosystems. The entry route of nanomaterials into the environment includes both natural and anthropogenic sources. In order to achieve sustainable and safe use of nanotechnological products in agriculture, similar environmental conditions must be simulated on lab scale with the careful selection of organisms related to agriculture. Thus, emphasis should be placed on the judicial use of nano-enabled products without compromising the sustainability of the environment and human health. This comprehensive book highlights recent field research as well as contributions from academicians in the lab. This book addresses the major aspects related to nanotechnology, biofortification of crops, and human and environmental health.
    Type of Medium: Online Resource
    Pages: XII, 349 p. 57 illus., 54 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031351471
    Series Statement: Sustainable Plant Nutrition in a Changing World,
    DDC: 620.5
    Language: English
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  • 4
    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Neurosciences. ; Biotechnology. ; Pharmacology. ; Neuroscience. ; Biotechnology. ; Pharmacology.
    Description / Table of Contents: Epidemiology of tinnitus -- Genetics and tinnitus -- Pharmacological modelling of tinnitus in animals -- Animal models of sensory and brain stimulation effects on tinnitus -- Cochlear damage and the mechanisms of tinnitus - implications for treatments -- Functional neuroanatomy of tinnitus -- Neuroinflammation and tinnitus -- Using big data to guide therapy development -- Pharmacoltherapy for tinnitus -- Sound therapy devices and mechanisms -- Cochlear electrical stimulation -- Brain stimulation -- Biomodal stimulation -- Effect of tinnitus on attention and cognition -- Neurobiology of stress induced tinnitus -- Behavioral correlates of tinnitus -- Psychological aprroaches to tinnitus management -- Momentary evaluation -- Questionnaires -- Psychoacoustic evaluation of tinnitus.
    Abstract: The origins of tinnitus and the development of effective treatments to treat tinnitus have puzzled scientists and clinicians for centuries. Now ground breaking research is beginning to unlock its secrets. The Behavioral Neuroscience of Tinnitus provides critical and comprehensive discussions of the most recent developments in behavioral neuroscience research of tinnitus. Each chapter represents the most important contemporary account of the subject, with an emphasis on preclinical and clinical trials for the development of new diagnostics and therapeutics. New and emerging innovative approaches are covered whenever possible. Six topics are discussed in detail in this volume, which provide new insights in the etiology and mechanisms of tinnitus, new biomarkers towards objective and reliable diagnosis of tinnitus, pharmacological approaches towards curing tinnitus, bioengineering advances towards developing effective medical devices, as well as the latest in psychotherapy methods. The reviews in the volume expose researchers and clinicians, both new and experienced, to exciting advancements and state-of-the-art developments from preeminent researchers in the field of tinnitus.
    Type of Medium: Online Resource
    Pages: XI, 487 p. 100 illus., 30 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030855031
    Series Statement: Current Topics in Behavioral Neurosciences, 51
    DDC: 612.8
    Language: English
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