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  • 1
    Electronic Resource
    Electronic Resource
    Evidence for an additional cattle DQB locus (1999)
    Springer
    Immunogenetics 49 (1999), S. 879-885 
    Details
    ISSN: 1432-1211
    Keywords: Key words MHC ; Cattle ; DQB ; BoLA-DQB5 ; Haplotype
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Abstract  Studying the genetic polymorphism of the major histocompatibility complex class II genes in cattle, we identified a sequence (KUH1) which resembles those encoding class II β chains. The gene was shown to be transcribed in peripheral blood leukocytes. Sequence comparisons, Southern blot, and phylogenetic analyses indicate that (1) KUH1 represents a distinct DQB locus, which we propose to designate BoLA-DQB5, (2) DQB5 constitutes an ancient DQB locus which diverged from a common ancestor gene prior to the duplication resulting in DQB1 and DQB2, (3) DQB5 is associated with haplotypes which contain DQA5 and a duplicated DQ region.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s002510050568
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  • 2
    Electronic Resource
    Electronic Resource
    Evidence for an additional cattle DQA locus, BoLA-DQA5 (1999)
    Springer
    Immunogenetics 49 (1999), S. 321-327 
    Details
    ISSN: 1432-1211
    Keywords: Key words MHC ; Haplotype ; Cattle ; DQA ; BoLA-DQA4
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Abstract  Studying the genetic polymorphism of the major histocompatibility complex class II genes in cattle, we identified an allele (BNI13) which encodes a typical class II α chain. Its transcription was confirmed by RNA analysis. Sequence comparisons, Southern blot, and phylogenetic analyses indicate that (1) BNI13 represents a distinct DQA locus which we propose to designate BoLA-DQA5, (2) BoLA-DQA1 and BoLA-DQA5 separated after the divergence of BoLA-DQA1 and BoLA-DQA2, but prior to the separation of sheep DQA1 and cattle DQA1, and (3) DQA5 is distributed among various cattle breeds but is confined to certain haplotypes.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s002510050499
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    Paper (German National Licenses)
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