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  • 2020-2024  (2,208)
  • 2005-2009  (36,848)
  • 1940-1944  (1,548)
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Year
  • 1
    Online Resource
    Online Resource
    Improving Potassium Recommendations for Agricultural Crops (2021)
    Cham :Springer International Publishing :
    Details
    Keywords: Agriculture. ; Botanical chemistry. ; Soil science. ; Applied ecology. ; Agriculture. ; Plant Biochemistry. ; Soil Science. ; Applied Ecology.
    Description / Table of Contents: The Potassium Cycle and Its Relationship to Recommendation Development -- Inputs: Potassium Sources for Agricultural Systems -- Outputs: Potassium Losses from Agricultural Systems -- Rhizosphere Processes and Root Traits Determining the Acquisition of Soil Potassium -- Potassium Use Efficiency of Plants -- Considerations for Unharvested Plant Potassium -- Considering Soil Potassium Pools with Dissimilar Plant Availability -- Using Soil Tests to Evaluate Plant Availability of Potassium in Soils -- Evaluating Plant Potassium Status -- How Closely is Potassium Mass Balance Related to Soil Test Changes -- Assessing Potassium Mass Balances in Different Countries and Scales -- Considerations for Selecting Potassium Placement Methods in Soil -- Timing Potassium Applications to Synchronize with Plant Demand -- Broadening the Objectives of Future Potassium Recommendations -- Improving Human Nutrition: A Critical Objective for Potassium Recommendations for Agricultural Crops.
    Abstract: This open access book highlights concepts discussed at two international conferences that brought together world-renowned scientists to advance the science of potassium (K) recommendations for crops. There was general agreement that the potassium recommendations currently in general use are oversimplified, outdated, and jeopardize soil, plant, and human health. Accordingly, this book puts forward a significantly expanded K cycle that more accurately depicts K inputs, losses and transformations in soils. This new cycle serves as both the conceptual basis for the scientific discussions in this book and a framework upon which to build future improvements. Previously used approaches are critically reviewed and assessed, not only for their relevance to future enhancements, but also for their use as metrics of sustainability. An initial effort is made to link K nutrition in crops and K nutrition in humans. The book offers an invaluable asset for graduate students, educators, industry scientists, data scientists, and advanced agronomists.
    Type of Medium: Online Resource
    Pages: XX, 455 p. 113 illus., 86 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030591977
    URL: https://doi.org/10.1007/978-3-030-59197-7
    DOI: 10.1007/978-3-030-59197-7
    DDC: 630
    Language: English
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  • 2
    Unknown
    The Nature and Origin of Compression in Passive Margins (2008)
    London : The Geological Society
    Details
    Description / Table of Contents: Increasingly, researchers have reported that passive margins do not show a simple uninterrupted thermal sag pattern of post-rift subsidence following continental separation. Rather, the structural and stratigraphic development of such margins may record evidence of complex phases of differential subsidence, exhumation and fold development. Some of the fold structures observed on passive continental margins appear to be related to regional stresses transmitted through basement rocks, whereas others are related to gravitational sliding and toe-thrusting. This special publication concentrates on the first of these categories. The morphology and distribution of such folds, together with potential mechanisms for generation of regional stress, are described in a series of papers by authorities in the field. As well as being an enigmatic feature of passive margin geology, the compressive folds have significance in the exploration for petroleum.
    Pages: Online-Ressource (VIII, 220 Seiten)
    ISBN: 9781862392618
    URL: http://sp.lyellcollection.org/content/vol306/issue1/
    Language: English
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  • 3
    Online Resource
    Online Resource
    Organotypic Models in Drug Development (2021)
    Cham :Springer International Publishing :
    Details
    Keywords: Pharmacology. ; Medical genetics. ; Pathology. ; Pharmacology. ; Clinical Genetics. ; Pathology.
    Description / Table of Contents: Inflammatory skin disease models in vitro and in animals – predictability for drug development -- Neural In Vitro Models for Studying Substances Acting on the Central Nervous System -- Quality of commercial tissues Standardised Reconstructed Skin Models in Toxicology and Pharmacology: State of the Art and Future Development -- Human-Derived In Vitro Models Used for Skin Toxicity Testing Under REACh -- Disease Models: Lung models for testing drugs against inflammation and infection -- In Vitro Models of the Blood-Brain Barrier -- How Qualification of 3D Disease Models Cuts the Gordian Knot in Preclinical Drug Development -- The CAM Assay as an Alternative In Vivo Model for Drug Testing -- Organotypic Models in Drug Development “Tumor Models and Cancer Systems Biology for the Investigation of Anticancer Drugs and Resistance Development -- Tissue Engineering for Musculoskeletal Regeneration and Disease Modeling -- Immunocompetent human intestinal models in preclinical drug development -- Engineered Heart Muscle Models in Phenotypic Drug Screens.
    Abstract: This book provides latest findings in organotypic models in drug development and provides the scientific resonance needed in an emerging field of research in disciplines, such as molecular medicine, physiology, and pathophysiology. Today the research on human-based test systems has gained major interest and funding in the EU and the US has increased over the last years. Moreover, so-called 3R (reduce, replace, refine animal experiments) centres have been established worldwide.
    Type of Medium: Online Resource
    Pages: VIII, 323 p. 70 illus., 37 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030700638
    Series Statement: Handbook of Experimental Pharmacology, 265
    URL: https://doi.org/10.1007/978-3-030-70063-8
    DOI: 10.1007/978-3-030-70063-8
    DDC: 615
    Language: English
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  • 4
    Online Resource
    Online Resource
    Mexican Fauna in the Anthropocene (2023)
    Cham :Springer International Publishing :
    Details
    Keywords: Biodiversity. ; Biotic communities. ; Conservation biology. ; Ecology . ; Vertebrates. ; Invertebrates. ; Biodiversity. ; Ecosystems. ; Conservation Biology. ; Vertebrate Zoology. ; Invertebrate Zoology.
    Description / Table of Contents: 1.1 General Introduction Principal -- 2. Zoloogical Groups -- 2.1 Arachnids -- 2.2 Insects: Migrants, endemics, and old to new pests -- 2.3 Freshwater decapod crustaceans: the challenges of documenting and preserving a very diverse fauna -- 2.4 Mexican molluscs: In the process of a 'silent extinction' -- 2.5 Amphibians and reptiles -- 2.6 Anthropocene impacts on the Mexican freshwater fish fauna -- 2.7 Mexican avifaunas of the Anthropocene -- 2.8 Marine birds -- 2.9 Terrestrial mammals -- 2.10 Marine mammals -- 2.11Mexican bats: conservation challenges in the Anthropocene -- 3. Ecosytems -- 3.1 The impact of the growth of urban environments on Mexican fauna -- 3.2 Anchialine fauna of the Yucatan Peninsula -- 3.3 Semi-terrestrial and aquatic invertebrates and fish in mangroves in México -- 3.4 Defaunation of Mexican tropical forests3.5 Mezcal boom and extinction debts in Mexican arid ecosystems -- 3.6 Deep sea life -- 3.7 The importance of agroecosystems for the Mexican fauna -- 3.8 The salamanders of the Mexican cloud forest -- 3.9 Human effects on caves in Mexico -- 3.10 Fauna of lakes and rivers -- 3.11 Coral reef faunal assemblages in the Mexican Caribbean: assessing the cryptic biodiversity -- 4 Processes -- 4.1 Contemporary climate change impacts on Mexican fauna -- 4.2 Invasive alien species of invertebrates and fishes introduced to Mexican freshwater systems -- 4.3 Are marine fisheries sustainable? -- 4.4 Pest dynamics in Mexican forests -- 4.5 Pollination by wild and managed animal vectors -- 4.6 Social participation strategies for the conservation of Mexican fauna -- 4.7 Citizen science for deep ocean biodiversity: a crowdsourcing tool in support of conservation -- 4.8 Legal actions for the conservation of fauna.
    Abstract: This contributed volume presents an analysis of the current conservation status of major faunal groups in Mexico. The chapters describe a prognosis of future challenges, and also explore the expanding threats inherent in the Anthropocene within the context of the unique physical, biological and cultural aspects of the nation. Covering 27 chapters, and written by Mexican and international authors, this book analyzes a wide range of vertebrate and invertebrate animal taxa, their ecosystems and the critical processes related to their present conservation status. This volume is an important reference material for researchers, conservationists and students interested in the biological and ecological processes shaping the Mexican fauna.
    Type of Medium: Online Resource
    Pages: XVII, 597 p. 50 illus. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031172779
    URL: https://doi.org/10.1007/978-3-031-17277-9
    DOI: 10.1007/978-3-031-17277-9
    DDC: 333.95
    Language: English
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  • 5
    Online Resource
    Online Resource
    Pigments, Pigment Cells and Pigment Patterns (2021)
    Singapore :Springer Nature Singapore :
    Details
    Keywords: Cytology. ; Developmental biology. ; Zoology. ; Biochemistry. ; Evolution (Biology). ; Psychobiology. ; Human behavior. ; Cell Biology. ; Developmental Biology and Stem Cells. ; Zoology. ; Chemical Biology. ; Evolutionary Biology. ; Behavioral Neuroscience.
    Description / Table of Contents: Part 1 Pigments and pigment organelles -- 1 Pigments in insects -- 2 Melanins in vertebrates -- 3 Body color expression in birds -- 4 Pigments in teleosts and their biosynthesis -- 5 Bioluminescence and Pigments -- Part 2 Pigment cell and patterned pigmentation -- 6 Development of melanin-bearing pigment cells in birds and mammals -- 7 Pigment cell development in teleosts -- 8 Pigment patterning in teleosts -- 9 Theoretical studies of pigment pattern formation -- 10 Evolution of Pigment Pattern Formation in Teleosts -- 11 Mechanisms of feather structural coloration and pattern formation in birds -- 12 Mechanism of color pattern formation in insects -- Part 3 Color changes -- 13 Physiological and Morphological Color Changes in Teleosts and in Reptiles -- 14 Color change in cephalopods -- 15 Physiological and biochemical mechanisms of insect color change towards understanding molecular links.
    Abstract: This book comprehensively summarizes the biological mechanisms of coloration and pattern formation of animals at molecular and cellular level, offering up-to-date knowledge derived from remarkable progress in the last 10 years. The brilliant coloration, conspicuous patterns and spectacular color changes displayed by some vertebrates and invertebrates are generally their strategies of the utmost importance for survival. Consists of mainly three parts, starts with introductory chapter, such as Pigments and Pigment Organelles, Developmental Genetics of Pigment Cell Formation, Adult Pigment Patterns, and Color Changes, this book introduces new pigment compounds in addition to classically known pigments and organelles, explains how the generation of multiple types of pigment cell is genetically controlled, describes the mechanisms underlying the zebrafish stripe formation as well as other animals and also summarizes the mechanism of physiological and morphological color changes of teleost, amphibian and cephalopod. Written by experts in the field, this book will be essential reading for graduate students and researchers in biological fields who are interested in pigmentation mechanisms of animals.
    Type of Medium: Online Resource
    Pages: XII, 472 p. 192 illus., 153 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9789811614903
    URL: https://doi.org/10.1007/978-981-16-1490-3
    DOI: 10.1007/978-981-16-1490-3
    DDC: 571.6
    Language: English
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  • 6
    Online Resource
    Online Resource
    Formulating Poorly Water Soluble Drugs (2022)
    Cham :Springer International Publishing :
    Details
    Keywords: Pharmaceutical chemistry. ; Pharmacology. ; Clinical biochemistry. ; Pharmaceutics. ; Pharmacology. ; Medical Biochemistry.
    Description / Table of Contents: Route-Specific Challenges in the Delivery of Poorly Water-Soluble Drugs -- Optimizing the Formulation of Poorly Water-Soluble Drugs -- Solid-State Techniques for Improving Solubility -- Mechanical Particle-Size Reduction Techniques -- Co-solvent and Complexation Systems -- Injectable Formulations of Poorly Water-Soluble Drugs -- Lipid-Based Formulations -- Structured Development Approach for Amorphous Systems -- Melt Extrusion -- Spray-Drying Technology -- Pharmaceutical Cryogenic Technologies -- Precipitation Technologies for Nanoparticle Production -- Emerging Technologies to Increase the Bioavailability of Poorly Water-Soluble Drugs -- Scientific and Regulatory Considerations for Development and Commercialization of Poorly Water-Soluble Drugs.
    Abstract: The objective of this third edition is to consolidate within a single text the most current knowledge, practical methods, and regulatory considerations pertaining to formulations development with poorly water-soluble molecules. A pharmaceutical scientist’s approach toward solubility enhancement of a poorly water-soluble molecule typically includes detailed characterization of the compound’s physiochemical properties, solid-state modifications, advanced formulation design, non-conventional process technologies, advanced analytical characterization, and specialized product performance analysis techniques. The scientist must also be aware of the unique regulatory considerations pertaining to the non-conventional approaches often utilized for poorly water-soluble drugs. One faced with the challenge of developing a drug product from a poorly soluble compound must possess at a minimum a working knowledge of each of the above mentioned facets and detailed knowledge of most. In light of the magnitude of the growing solubility problem to drug development, this is a significant burden especially when considering that knowledge in most of these areas is relatively new and continues to develop. Highlights the most recent advancements reported in the literature on technologies to improve the dissolution and bioavailability of poorly water soluble drugs Provides a comprehensive discussion of new technologies developed and recently over 40% updated new content Essential read for scientists and researchers in pharmaceutical, chemical, and agricultural industries since over 80% of newly discovered drugs are poorly water soluble.
    Type of Medium: Online Resource
    Pages: XII, 693 p. 280 illus., 138 illus. in color. , online resource.
    Edition: 3rd ed. 2022.
    ISBN: 9783030887193
    Series Statement: AAPS Advances in the Pharmaceutical Sciences Series, 50
    URL: https://doi.org/10.1007/978-3-030-88719-3
    DOI: 10.1007/978-3-030-88719-3
    DDC: 615.19
    Language: English
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  • 7
    Online Resource
    Online Resource
    Managing Landscapes for Change (2020)
    Cham :Springer International Publishing :
    Details
    Keywords: Human geography. ; Environmental management. ; Agriculture. ; Physical geography. ; Energy policy. ; Energy and state. ; Human Geography. ; Environmental Management. ; Agriculture. ; Physical Geography. ; Energy Policy, Economics and Management.
    Description / Table of Contents: Chapter 1. Introduction -- Chapter 2. What is a Landscape? -- Chapter 3. Drivers of Landscape Change -- Chapter 4. Landscape Trajectories -- Chapter 5. Options for Managing Landscape for Change -- Chapter 6. Barriers to Managing for Change -- Chapter 7. Social and Institutional Innovations -- Chapter 8. Technologies for Innovating Forward -- Chapter 9. Conclusions and Recommendation.
    Abstract: This book discusses how future landscapes will be shaped by pervasive change and where, when, and how society should manage landscapes for change. Readers will learn about the major anthropogenic drivers of landscape change, including climate change and human induced disturbance regimes, and the unique consequences that multiple and simultaneously occurring change agents can have on landscapes. The author uses landscape trajectories as a guide to selecting the appropriate course of action, and considers how landscape position, inertia, and direction will determine landscape futures. The author introduces the concept of landscapes as socio-technical-ecological systems (STES), which combines ecological and technological influences on future landscape change and the need for society to acknowledge both when considering landscape management. Thinking beyond solutions, the author identifies barriers to managing landscapes for change including the cost, cultural identity of local populations, and the fear of taking action under uncertain conditions. Nevertheless, processes, tools, and technologies exist for overcoming social and ecological barriers to managing landscapes for change, and continued investment in social and scientific infrastructure holds out hope for maintaining our landscape values even as we enter an era of unprecedented change and disruption.
    Type of Medium: Online Resource
    Pages: XI, 111 p. 36 illus., 25 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030620417
    Series Statement: Landscape Series, 27
    URL: https://doi.org/10.1007/978-3-030-62041-7
    DOI: 10.1007/978-3-030-62041-7
    DDC: 304.2
    Language: English
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  • 8
    Online Resource
    Online Resource
    Glycobiology of the Nervous System (2023)
    Cham :Springer International Publishing :
    Details
    Keywords: Neurosciences. ; Zoology. ; Neurochemistry. ; Neuroscience. ; Zoology. ; Neurochemistry.
    Description / Table of Contents: 1. Introduction to the complexity of cell surface and tissue matrix glycoconjugates. -- 2. Introduction to cells comprising the nervous system. -- 3. Synthesis -- processing -- and function of N-glycans in N-glycoproteins. -- 4. Synthesis of O-linked glycoconjugates in the nervous system. -- 5. Chemistry and function of glycosaminoglycans in the nervous system. -- 6. Use of glycan-targeted antibodies/lectins to study the expression/function of glycosyltransferases in the nervous system. -- 7. Capillary electrophoresis and mass spectrometry-based glycosylation analysis in glycomics and glycoproteomics. -- 8. Structural analysis of oligosaccharides and glycoconjugates using NMR. -- 9. Glycolipid and glycoprotein expression during neural development. -- 10. Gangliosides and cell surface ganglioside glycohydrolases in the nervous system (request them to include gal-cer and sulfatide). -- 11. Role of myelin-associated glycoproteins in the peripheral nervous system. -- 12. Glycosignaling: a general review. -- 13. Glycosphingolipids in the regulation of the nervous system. -- 14. O-GlcNAcylation of neuronal proteins: Roles in neuronal functions and in neurodegeneration. -- 15. Glycoconjugates in nuclear membranes. -- 16. N-glycosylation in regulation of the nervous system. -- 17. Role of carbohydrates in the interaction of pathogens with neural cells. -- 18. Glycoconjugate changes in aging and age-related diseases. -- 19. Gangliosides and glycolipids in neurodegenerative disorders. -- 20. Inborn errors of glycosphingolipid catabolism and potential treatment. -- 21. Neurological aspects of human glycosylation disorders. -- 22. Glycoconjugates and neural tumors. -- 23. Galectins and neuroinflammation . -- 24. Glycoconjugates and neuroimmunological diseases. -- 25. Targeting nanoparticle drug carriers to the brain. -- 26. Use of quantum dots to treat inherited lysosomal storage diseases. -- 27. MALDI-FTICR MS imaging of nervous system glycoconjugates.
    Abstract: This new edition provides comprehensive coverage of the variety and complexity of the roles that glycoconjugates play in the cells of the nervous system. Basic fundamental principles as well as the latest developments in neural glycobiology are discussed. Topics covered range from the structure and metabolism of the saccharide chains and current approaches used in their study, to changes glycoconjugates undergo during development and aging of the nervous system and the roles they have in neurological disease. New topics include a detailed discussion of cells found within the nervous system, an extensive listing of congenital disorders of glycosylation of both proteins and lipids, the roles of glycans in neuronal axon growth/guidance and voltage-gated channels, the role of intra-lysosomal luminal vesicles in lysosomal storage disorders, and, in the time of the COVID-19 pandemic, the role of carbohydrates in infection by SARS-CoV-2. The breadth and depth of topics covered make this an essential reference for those new to the field as well as for more experienced investigators.
    Type of Medium: Online Resource
    Pages: XII, 501 p. 96 illus., 73 illus. in color. , online resource.
    Edition: 2nd ed. 2023.
    ISBN: 9783031123900
    Series Statement: Advances in Neurobiology, 29
    URL: https://doi.org/10.1007/978-3-031-12390-0
    DOI: 10.1007/978-3-031-12390-0
    DDC: 612.8
    Language: English
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  • 9
    Online Resource
    Online Resource
    Agricultural Ethics - An Invitation (2020)
    Cham :Springer International Publishing :
    Details
    Keywords: Agriculture. ; Applied ethics. ; Soil science. ; Environment. ; Agriculture. ; Agricultural Ethics. ; Soil Science. ; Environmental Sciences.
    Description / Table of Contents: 1. Introduction -- 2. From Weed Control To Ethics -- 3. Agriculture- A Brief History -- 4. World Population - Three Views -- 5. Agricultures Moral Dilemmas -- 6. Ethics in Agriculture and Other Disciplines -- 7. Seeking Common Ground -- 8. Ethical Puzzles.
    Abstract: I write because I am concerned that I and my agricultural colleagues have avoided addressing the moral dimension of the environmental and social problems we have contributed to. I hope for an exchange of ideas about agriculture's moral dilemmas. I encourage my readers to engage in a collective conversation about the dilemmas and avoid remaining in what Merton calls "the collective arrogance and despair of his own herd." If those engaged in agriculture continue to ignore and fail to realize our common difficulties they will be addressed and resolved by societal pressure and political action, which may not yield the resolution we favor. The book's goal is not to resolve the moral dilemmas raised. It is to raise them and encourage thought and discussion. It will ask but not answer why nearly all involved in agriculture have not addressed the moral concerns voiced by the general public. The agricultural enterprise is committed to the benefits and future success of the present, very productive, chemical, capital, and energy intensive system, which is, in the minds of many, not sustainable. The internal justification invokes the moral claim that they feed the world's population. The question remains whether or not the prevailing moral justification of feeding the world is adequate given all the issues modern, developed country agriculture faces: pesticides in soil, water, and food, cruelty to animals, Biotech/GMO's, corporate agriculture, pollution by animal factory waste, exploitation of and cruelty to migrant labor.
    Type of Medium: Online Resource
    Pages: XI, 173 p. 2 illus., 1 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030489359
    URL: https://doi.org/10.1007/978-3-030-48935-9
    DOI: 10.1007/978-3-030-48935-9
    DDC: 630
    Language: English
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  • 10
    Online Resource
    Online Resource
    Research for Medical Imaging and Radiation Sciences (2021)
    Cham :Springer International Publishing :
    Details
    Keywords: Biotechnology. ; Radiology. ; Biomedical engineering. ; Biotechnology. ; Radiology. ; Biomedical Engineering and Bioengineering. ; Radiology.
    Description / Table of Contents: 1. The Nature and Scope of Research -- 2. Quantitative and Qualitative Approaches to Research-An Overview of Approaches -- 3. Planning Your Research -- 4. The Literature Review -- 5. Quantitative Research Methods -- 6. Qualitative Research Methods -- 7. Data Collection, Analysis and Interpretation -- 8. Communicating Research Findings -- 9. Research Examples in Medical Imaging-A Selected Review.
    Abstract: This book addresses essential principles of research according to the scientific method for medical imaging technology research. The scope of this book covers the nature of scientific research; quantitative and qualitative approaches essentials; research planning; literature review fundamentals; research methods; data collection, analysis, and interpretation; and communicating research findings. The book meets the educational requirements on Research Principles and Concepts (for entry to practice) of the following professional radiologic technology associations: the American Society of Radiologic Technologists (ASRT), the Canadian Association of Medical Radiation Technologists (CAMRT), the College of Radiographers in the United Kingdom, and radiography societies and associations in Asia, Australia, Europe, and Africa. This is an ideal book for radiologic technologists, nuclear medicine technologists, and radiation therapists seeking to get started in research in their profession. Additionally, biomedical imaging engineering technologists, radiologists, and medical imaging physicists may use this as a “guiding principles” textbook.
    Type of Medium: Online Resource
    Pages: XVII, 215 p. 53 illus., 38 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030799564
    URL: https://doi.org/10.1007/978-3-030-79956-4
    DOI: 10.1007/978-3-030-79956-4
    DDC: 660.6
    Language: English
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