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  • Fine structure  (9)
  • Prebiotic  (6)
  • Springer  (15)
  • 2020-2024
  • 2010-2014
  • 1970-1974  (15)
  • 1945-1949
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Keywords
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  • Springer  (15)
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Year
  • 1
    Electronic Resource
    Electronic Resource
    Further studies of urea-catalyzed phosphorylation reactions (1973)
    Springer
    Journal of molecular evolution 2 (1973), S. 231-234 
    Details
    ISSN: 1432-1432
    Keywords: Phosphorylation ; Nucleotides ; Nucleoside Polyphosphates ; Oligonucleotides ; Urea ; Prebiotic
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Summary We have analyzed the products formed when mixtures of a nucleoside and ammonium dihydrogen phosphate are heated with an excess of urea. If there is more phosphate than nucleoside in the mixture, compounds containing pyrophosphate bonds are obtained. If uridine, as nucleoside, is in excess over phosphate, di- and oligonucleotides are formed.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01654004
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  • 2
    Electronic Resource
    Electronic Resource
    Studies in prebiotic synthesis. VII (1972)
    Springer
    Journal of molecular evolution 1 (1972), S. 249-257 
    Details
    ISSN: 1432-1432
    Keywords: Prebiotic ; Nucleosides ; Dry-phase ; Seawater
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Summary The purine nucleosides (adenosine, guanosine, inosine, xanthosine) are formed when the corresponding purine bases and D-ribose are heated together in the presence of certain salts and minerals. The salts remaining after the evaporation of seawater are particularly effective in these syntheses. The relevance of these reactions for prebiological evolution is discussed.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01660244
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  • 3
    Electronic Resource
    Electronic Resource
    On the possible role of crystals in the origins of life (1974)
    Springer
    Journal of molecular evolution 3 (1974), S. 141-150 
    Details
    ISSN: 1432-1432
    Keywords: Adsorption ; Clay ; Montmorillonite ; Phosphoramidates ; Polymerization ; Prebiotic
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Summary Nucleoside phosphoramidates derived from polyamines containing at least three amine groups are strongly adsorbed by sodium and magnesium montmorillonite clays even from very dilute solutions. Heating the dried clay-phosphoramidate mixture results in the production of small amounts of the dinucleotides.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01796559
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  • 4
    Electronic Resource
    Electronic Resource
    Catalysts for the self-polymerization of adenosine cyclic 2′,3′-phosphate (1973)
    Springer
    Journal of molecular evolution 2 (1973), S. 303-316 
    Details
    ISSN: 1432-1432
    Keywords: Polymerization ; Phosphorylation ; Adenosine Cyclic 2′,3′-phosphate ; Oligonucleotides ; Amines ; 2-Aminoethanol ; Amino Acids ; Prebiotic
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Summary When adenosine cyclic 2′,3′-phosphate is evaporated from solution in the presence of simple catalysts such as aliphatic diamines at alkaline pH, and maintained in a dry state at moderate temperatures (25-85°C), self-polymerization to give oligonucleotides of chainlength up to at least 6 is observed. The products contain an excess of [3′→5′]-linkages over [2′→5′]-linkages. The effects of different catalysts and reaction conditions on the efficiency of the reaction are described. The prebiological relevance of these reactions is discussed.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01654098
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  • 5
    Electronic Resource
    Electronic Resource
    The possible role of inorganic thiophosphate as a prebiotic phosphorylating agent (1974)
    Springer
    Journal of molecular evolution 3 (1974), S. 317-321 
    Details
    ISSN: 1432-1432
    Keywords: Thiophosphate ; Thymidine ; Phosphorylation of Nucleosides ; Prebiotic
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Summary It is proposed that inorganic thiophosphate was a versatile and highly reactive constituent of the primitive earth. Some of the ramifications of this assumption with regard to prebiotic chemistry stem from the dual nature of thiophosphate as the most superior nucleophilic agent and an energy rich phosphate. The Michael addition of thiophosphate to acrylonitrile yieldsS-cyanoethylphosphorothioate in high yield. This compound in turn can be used to phosphorylate 2′-deoxythymidine in organic solvents and in the solid state. A mixture of 5′ and 3′-dTMP were identified via chromatography, elementary analysis and NMR spectroscopy.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01796047
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  • 6
    Electronic Resource
    Electronic Resource
    Polyphosphate and trimetaphosphate formation under potentially prebiotic conditions (1972)
    Springer
    Journal of molecular evolution 1 (1972), S. 241-248 
    Details
    ISSN: 1432-1432
    Keywords: Urea ; Ammonium Dihydrogen Phosphate ; Nucleoside ; Prebiotic ; Polyphosphate ; Trimetaphosphate
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Summary When ammonium dihydrogen phosphate is heated with urea to temperatures in the range 85–100°C, it polymerizes almost quantitatively to give polyphosphates containing, on the average, more than ten (PO3) residues. Similar experiments carried out at 72°C give polyphosphate in more than 60% yield. If a nucleoside (thymidine or 3′-deoxythymidine) is added to the reaction mixture, up to 23% of trimetaphosphate can be obtained at 100°C. The prebiotic significance of these reactions is discussed.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01660243
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  • 7
    Electronic Resource
    Electronic Resource
    The structure of the terminal sensilla on the maxillary palps of Locusta migratoria (L.), and changes associated with moulting (1971)
    Springer
    Cell & tissue research 121 (1971), S. 48-68 
    Details
    ISSN: 1432-0878
    Keywords: Chemoreceptor ; Locusta ; Fine structure ; Development ; Moulting
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary The basic structure of the terminal sensilla of Locusta migratoria resembles that of Schistocerca gregaria. There are commonly six or ten neurons whose dendrites extend almost to the opening of the peg. Proximally the dendrites are clothed by a neurilemma cell which also encloses a basal cavity through which their ciliary region passes. The tormogen cell encloses the receptor-lymph cavity and actively secretes material into it. The receptor-lymph cavity and the basal cavity are quite separate. The development of new pegs at a moult is described. After apolysis the scolopale extends across the subcuticular space and protects the dendrites, which remain in a functional condition until shortly before ecdysis. As the trichogen cell grows out to form a new peg the tip is surrounded by a mass of electron-dense material, probably derived from the receptorlymph cavity. The function of this material is unknown. Regeneration of the dendrites is considered. The possible mechanism by which the tip of the peg opens and closes is considered and the general structure of the organule is discussed in relation to functioning.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00330916
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  • 8
    Electronic Resource
    Electronic Resource
    Sensory innervation of the tentacles of the polychaete, Sabella pavonina (1971)
    Springer
    Cell & tissue research 122 (1971), S. 160-171 
    Details
    ISSN: 1432-0878
    Keywords: Tentacles ; Polychaetes ; Sensory cells ; Sensory innervation ; Cilia ; Fine structure
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary Following observation of conical groups of stiff, but motile cilia on the tentacles of the branchial crown of Sabella pavonina, these were examined with the electron microscope. The bundles consist of about 40 unenclosed “standard” cilia supported by one or two primary sense cells with centrally directed axons of 0.1–0.2 μ diameter. Axons in the distal portions of the branchial crown occur in small bundles surrounded by a basement membrane. More centrally, glial elements appear and the nerves are surrounded by a collagenous sheath. The branchial nerve trunk shows similarities in organisation to other previously investigated annelid central nervous tissue in that the whole nerve is surrounded by a fibrous sheath central to which there is a layer of glial cells with processes penetrating a central neuropile. The 0.1–0.2 μ axons commonly occur in glial-enveloped groups of 〈 40 whilst other axons of larger and mixed diameter are found together. Each tentacle has two branchial nerves on the oral side, and each nerve gives rise to two small 75-axon branches running to each pinnule. The branchial nerves fuse to form the branchial nerve trunk running to the supra-oesophageal ganglia. Sections of the branchial nerves of the branchial crown at progressively more central levels show that the branchial nerve trunk contains enough axons of 0.1–0.2 μ diameter to account for all the sensory cells on the tentacles. This is taken as evidence for the sensory cells having axons terminating within the central nervous system and that there is no peripheral confluence or fusion of these afferent axons.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00337627
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  • 9
    Electronic Resource
    Electronic Resource
    The ultrastructural effects of triparanol on rat atrial muscle (1972)
    Springer
    Cell & tissue research 131 (1972), S. 27-30 
    Details
    ISSN: 1432-0878
    Keywords: Atrial muscle ; Fine structure ; Triparanol
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary The atrial musculature of rats given the cholesterol inhibitor triparanol (MER/29) (250 mg/kg daily) for 8 days was examined under the electron microscope and compared with that from untreated animals. The sarcoplasmic core of muscle fibers from animals given triparanol exhibited a new formation of sarcoplasmic granules which displayed a crystalline latticework with opaque lines approximately 40–60 Å separated by clear spaces 50–70 Å. They were partially or completely surrounded by a membrane. The crystalline bodies in cardiac muscle fibers were not as numerous as those observed in adrenocortical, testicular interstitial, or luteal cells as reported earlier by the investigators.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00307198
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  • 10
    Electronic Resource
    Electronic Resource
    Ultrastructural and histochemical studies on the innervation of the heart of a teleost, pleuronectes platessa L. (1972)
    Springer
    Cell & tissue research 131 (1972), S. 519-528 
    Details
    ISSN: 1432-0878
    Keywords: Cardiac innervation ; Teleosts ; Acetylcholinesterase ; Fine structure ; Histochemistry
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary The innervation of the heart of the plaice has been studied ultrastructurally and histochemically in order to describe the anatomy, and the nature of the neuro-transmitters involved in the regulation of the heart. A single cardiac branch of the vagus runs over the Duct of Cuvier and sinus venosus where it forms a plexus extending into the sinoatrial region. Many ganglion cells are scattered throughout this plexus upon which are seen cholinergic-type terminals at which AChE can be localised. It is therefore concluded that this is the parasympathetic cardiac ganglion. The innervation of the atrium is dense at the sinoatrial end but decreases towards the ventricle. The ventricle is probably aneural, possibly a consequence of the lack of a coronary blood supply to act as a pathway for an innervation of this chamber. Most of the intramural axon profiles contain large numbers of small agranular vesicles and are cholinergic, AChE being localised at their membranes. Other profiles contain small numbers of larger granular vesicles amongst the agranular vesicles but these are not adrenergic since these vesicles are not depleted by reserpine, do not load with 6-OHDA, and AChE can be localised at the membranes of the profiles. No adrenergic-type profiles were seen in any part of the heart, nor were any fluorescent, catecholamine-containing fibres observed.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00306968
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