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  • 1
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    Taylor & Francis | Oceanography and Marine Biology | Oceanography and Marine Biology | CRC Press
    Publication Date: 2024-01-30
    Description: The 100-year record of daily sea-surface temperature (SST) acquired at the Hopkins Marine Station (HMS) in Pacific Grove, California, is one of the longest oceanographic records in existence. It is exceeded in length by the record at Scripps Pier by only 3 years. The history of the record at HMS, the methods used to gather the data, the problems that were encountered, and finally, the scientific significance of this record are presented. Reconstructing a complete version of the 100-year time series record was not straightforward. Two major gaps had to be filled using data from another site, and variation in the time of day for sample collection was addressed to better standardise the SST values presented. The observations were first examined for their oceanographic content based on the relevant timescales involved that ranged from daily to the record length, i.e., centennial. The major sources of variability included the El Niño phenomenon, the Pacific Decadal Oscillation, and the Marine Heat Wave (MHW) that began in 2014. The impact of the MHW cannot be overstated, and it was well represented in the data from the HMS. The use of the historical temperature record for studies of long-term changes in species and communities in the biological literature is highlighted. Finally, a set of conclusions is presented highlighting the important contributions of the SST dataset that are only possible through dedicated long-term environmental monitoring programmes such as the one reported here.
    Keywords: Daily Sea-Surface Temperature ; Hopkins Marine Station ; Monterey Bay ; 100-Year Record ; Physical Oceanography ; Marine Biology ; North Pacific Marine Heat Wave ; Coastal Laurence C. Breaker and San Diego State University ; bic Book Industry Communication::R Earth sciences, geography, environment, planning::RN The environment::RNC Applied ecology ; bic Book Industry Communication::W Lifestyle, sport & leisure::WN Natural history::WNW The Earth: natural history general ; bic Book Industry Communication::R Earth sciences, geography, environment, planning::RB Earth sciences::RBK Hydrology & the hydrosphere::RBKC Oceanography (seas) ; bic Book Industry Communication::T Technology, engineering, agriculture::TQ Environmental science, engineering & technology ; bic Book Industry Communication::R Earth sciences, geography, environment, planning::RN The environment::RNP Pollution & threats to the environment::RNPG Climate change ; bic Book Industry Communication::P Mathematics & science::PS Biology, life sciences::PSP Hydrobiology::PSPM Marine biology ; bic Book Industry Communication::P Mathematics & science::PS Biology, life sciences::PSA Life sciences: general issues::PSAF Ecological science, the Biosphere ; bic Book Industry Communication::P Mathematics & science::PS Biology, life sciences::PSA Life sciences: general issues::PSAJ Evolution ; bic Book Industry Communication::P Mathematics & science::PS Biology, life sciences
    Language: English
    Format: image/jpeg
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  • 2
    Electronic Resource
    Electronic Resource
    [S.l.] : American Institute of Physics (AIP)
    Journal of Applied Physics 64 (1988), S. 6858-6860 
    ISSN: 1089-7550
    Source: AIP Digital Archive
    Topics: Physics
    Notes: A new approach to ionizing radiation detection is proposed. The amount of ionization produced in a detector medium is measured by the heat generated as the charged carriers are drifted across the device under an applied voltage. The amount of energy generated can be orders of magnitude larger than that deposited by the radiation itself. A dramatic increase in detector mass can be achieved compared to simple calorimetric particle detectors for equivalent energy thresholds. It is possible to obtain a sensitivity level sufficient for single-carrier detection. The principle of operation has been demonstrated with an experimental device operated at a temperature of 1.8 K, and improved performance is expected at lower temperatures.
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    [S.l.] : American Institute of Physics (AIP)
    Journal of Applied Physics 59 (1986), S. 3734-3736 
    ISSN: 1089-7550
    Source: AIP Digital Archive
    Topics: Physics
    Notes: A new isotope-specific and quantitative technique based on self-detection in a position-sensitive detector has been developed for the imaging of radio-carbon clusters in high-purity Ge. Using a novel position-sensitive detector concept, a one-dimensional spatial resolution of ∼200 μm FWHM and a sensitivity of ∼6×107 14C atoms per cluster has been obtained. This technique can be applied to other semiconductors which can be used to fabricate self-counting position-sensitive nuclear radiation detectors.
    Type of Medium: Electronic Resource
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  • 4
    Electronic Resource
    Electronic Resource
    [S.l.] : American Institute of Physics (AIP)
    Journal of Applied Physics 59 (1986), S. 2213-2215 
    ISSN: 1089-7550
    Source: AIP Digital Archive
    Topics: Physics
    Notes: We have directly measured the excitation of electron-hole pairs at a crystal surface by ground-state neutral atoms. Utilizing seeded molecular beam techniques we have scattered hyperthermal (1–6 eV) Xe atoms from the (100) face of a Ge p-i-n diode and recorded the current transient induced due to the scattering process. We find the product of the excitation and collection probability to be ∼10−4 over a range of kinetic energies 2〈EXe(eV)〈6. The excitation of electron-hole pairs constitutes a small portion of the massive energy loss (ΔE/E∼70%) of the Xe atom to the crystal.
    Type of Medium: Electronic Resource
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  • 5
    Publication Date: 2018-11-19
    Description: The type VI secretion system (T6SS) is a supramolecular complex involved in the delivery of potent toxins during bacterial competition. Pseudomonas aeruginosa possesses three T6SS gene clusters and several hcp and vgrG gene islands, the latter encoding the spike at the T6SS tip. The vgrG1b cluster encompasses seven genes whose organization and sequences are highly conserved in P. aeruginosa genomes, except for two genes that we called tse7 and tsi7. We show that Tse7 is a Tox-GHH2 domain nuclease which is distinct from other T6SS nucleases identified thus far. Expression of this toxin induces the SOS response, causes growth arrest and ultimately results in DNA degradation. The cytotoxic domain of Tse7 lies at its C terminus, while the N terminus is a predicted PAAR domain. We find that Tse7 sits on the tip of the VgrG1b spike and that specific residues at the PAAR–VgrG1b interface are essential for VgrG1b-dependent delivery of Tse7 into bacterial prey. We also show that the delivery of Tse7 is dependent on the H1-T6SS cluster, and injection of the nuclease into bacterial competitors is deployed for interbacterial competition. Tsi7, the cognate immunity protein, protects the producer from the deleterious effect of Tse7 through a direct protein–protein interaction so specific that toxin/immunity pairs are effective only if they originate from the same P. aeruginosa isolate. Overall, our study highlights the diversity of T6SS effectors, the exquisite fitting of toxins on the tip of the T6SS, and the specificity in Tsi7-dependent protection, suggesting a role in interstrain competition.
    Print ISSN: 0027-8424
    Electronic ISSN: 1091-6490
    Topics: Biology , Medicine , Natural Sciences in General
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  • 6
    Publication Date: 2016-12-12
    Description: Circulating tumor cells (CTCs) are established cancer biomarkers for the “liquid biopsy” of tumors. Molecular analysis of single CTCs, which recapitulate primary and metastatic tumor biology, remains challenging because current platforms have limited throughput, are expensive, and are not easily translatable to the clinic. Here, we report a massively parallel, multigene-profiling nanoplatform to compartmentalize and analyze hundreds of single CTCs. After high-efficiency magnetic collection of CTC from blood, a single-cell nanowell array performs CTC mutation profiling using modular gene panels. Using this approach, we demonstrated multigene expression profiling of individual CTCs from non–small-cell lung cancer (NSCLC) patients with remarkable sensitivity. Thus, we report a high-throughput, multiplexed strategy for single-cell mutation profiling of individual lung cancer CTCs toward minimally invasive cancer therapy prediction and disease monitoring.
    Print ISSN: 0027-8424
    Electronic ISSN: 1091-6490
    Topics: Biology , Medicine , Natural Sciences in General
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  • 7
  • 8
    Publication Date: 2016-07-10
    Description: The challenge of characterizing subsurface fluid flow has motivated extensive laboratory studies, yet fluid-flow through rock specimens in which fractures are created and maintained at high-stress conditions remains under-investigated at this time. The studies of this type that do exist do not include in situ fracture geometry measurements acquired at stressed conditions, which would be beneficial for interpreting the flow behavior. Therefore, this study investigates the apparent permeability induced by direct-shear fracture stimulation through Utica shale (a shale gas resource and potential caprock material) at high triaxial-stress confinement and for the first time relates these values to simultaneously acquired in situ X-ray radiography and microtomography images. Change in fracture geometry and apparent permeability was also investigated at additional reduced stress states. Finite element and combined finite discrete element modeling were used to evaluate the in situ observed fracturing process. Results from this study indicate that the increase in apparent permeability through fractures created at high-stress (22.2 MPa) was minimal relative to the intact rock (less than 1 order of magnitude increase) while fractures created at low stress (3.4 MPa) were significantly more permeable (2 to 4 orders of magnitude increase). This study demonstrates the benefit of in situ X-ray observation coupled with apparent permeability measurement to analyze fracture creation in the subsurface. Our results show that the permeability induced by fractures through shale at high stress can be minor and therefore favorable in application to CO 2 sequestration caprock integrity but unfavorable for hydrocarbon recovery from unconventional reservoirs.
    Print ISSN: 0148-0227
    Topics: Geosciences , Physics
    Published by Wiley on behalf of American Geophysical Union (AGU).
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  • 9
    Publication Date: 2016-05-06
    Description: This paper provides a detailed analysis of momentum, angular momentum, vorticity, and energy budgets of a submesoscale front undergoing frontogenesis driven by an upper-ocean, submesoscale eddy field in a Large Eddy Simulation (LES). The LES solves the wave-averaged, or Craik-Leibovich, equations in order to account for the Stokes forces that result from interactions between nonbreaking surface waves and currents, and resolves both submesoscale eddies and boundary layer turbulence down to 4.9m × 4.9m × 1.25m grid scales. It is found that submesoscale frontogenesis differs from traditional frontogenesis theory due to four effects: Stokes forces, momentum and kinetic energy transfer from submesoscale eddies to frontal secondary circulations, resolved turbulent stresses, and unbalanced torque. In the energy, momentum, angular momentum, and vorticity budgets for the frontal overturning circulation, the Stokes shear force is a leading-order contributor, typically either the second or third largest source of frontal overturning. These effects violate hydrostatic and thermal wind balances during submesoscale frontogenesis. The effect of the Stokes shear force becomes stronger with increasing alignment of the front and Stokes shear and with a nondimensional scaling. The Stokes shear force and momentum transfer from submesoscale eddies significantly energize the frontal secondary circulation along with the buoyancy. This article is protected by copyright. All rights reserved.
    Print ISSN: 0148-0227
    Topics: Geosciences , Physics
    Published by Wiley on behalf of American Geophysical Union (AGU).
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  • 10
    Publication Date: 2016-11-07
    Description: Two degrees of global warming above the preindustrial level is widely suggested as an appropriate threshold beyond which climate change risks become unacceptably high. This “2 °C” threshold is likely to be reached between 2040 and 2050 for both Representative Concentration Pathway (RCP) 8.5 and 4.5. Resulting sea level rises will not be globally uniform, due to ocean dynamical processes and changes in gravity associated with water mass redistribution. Here we provide probabilistic sea level rise projections for the global coastline with warming above the 2 °C goal. By 2040, with a 2 °C warming under the RCP8.5 scenario, more than 90% of coastal areas will experience sea level rise exceeding the global estimate of 0.2 m, with up to 0.4 m expected along the Atlantic coast of North America and Norway. With a 5 °C rise by 2100, sea level will rise rapidly, reaching 0.9 m (median), and 80% of the coastline will exceed the global sea level rise at the 95th percentile upper limit of 1.8 m. Under RCP8.5, by 2100, New York may expect rises of 1.09 m, Guangzhou may expect rises of 0.91 m, and Lagos may expect rises of 0.90 m, with the 95th percentile upper limit of 2.24 m, 1.93 m, and 1.92 m, respectively. The coastal communities of rapidly expanding cities in the developing world, and vulnerable tropical coastal ecosystems, will have a very limited time after midcentury to adapt to sea level rises unprecedented since the dawn of the Bronze Age.
    Print ISSN: 0027-8424
    Electronic ISSN: 1091-6490
    Topics: Biology , Medicine , Natural Sciences in General
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