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  • Neurosecretion  (9)
  • Springer  (9)
  • 2020-2024
  • 2020-2023
  • 1975-1979  (9)
  • 1955-1959
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Keywords
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  • Springer  (9)
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Year
  • 1
    Electronic Resource
    Electronic Resource
    The hypothalamo-hypophysial system in acipenseridae (1976)
    Springer
    Cell & tissue research 170 (1976), S. 113-128 
    Details
    ISSN: 1432-0878
    Keywords: Neurohypophysis ; Neurosecretion ; Acipenseridae ; Spawning ; Stress
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary Neurohypophyses from sexually mature female sturgeons, Acipenser güldenstädti Brandt, killed before, soon after spawning, and during down-stream migration were studied light and electron microscopically. Ovaries were examined only under a light microscope. A large amount of neurosecretory material (3.5–4.5 arbitrary units) is found in the neurohypophysial “roots” during up-stream migration to spawning grounds. Neurosecretory fibres and their terminals are replete with elementary neurosecretory granules. Side by side with the latter some terminals contain single residual granules and few “synaptic” vesicles. Soon after spawning the amount of neurosecretory material decreases markedly in most individuals (content up to 1–3 units), and elementary granules are few in the fibres and their terminals. The number of residual granules increases, and “synaptic” vesicles are especially numerous. Granulated, disintegrating neurosecretory granules and granule-shadows occur in the preterminal parts of the fibres. The number of pituicytes increases because some “light” tanycytes seem to migrate from the ependymal into the subependymal layer. The restoration of neurosecretory material (reaching again up to 3.5–4.5 units) occurs within a month after spawning. The number of elementary granules increases in fibres and terminals while that of residual granules and “synaptic” vesicles decreases. These changes in the neurohypophysis of females after spawning are due to discharge of great amounts of peptide neurohormones into the general circulation after spawning. Spawning is regarded as a “physiological” stress for these females.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00220114
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  • 2
    Electronic Resource
    Electronic Resource
    Movement of neurosecretory product through the anatomical compartments of the neural lobe of the pituitary gland (1975)
    Springer
    Cell & tissue research 156 (1975), S. 483-497 
    Details
    ISSN: 1432-0878
    Keywords: Neurohypophysis ; Neurosecretion ; Neurophysin ; Neurohypophysia hormones ; Electron microscopy ; Autoradiography
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary Electron-microscope autoradiographs have been prepared from the neural lobes of the pituitary glands of rats which had received intracisternal injections of [35S] cysteine at various times before gland removal. The rate of appearance and disappearance of autoradiographically demonstrable radioactivity in the neural lobe closely paralleled that previously determined, biochemically, for radioactive hormones and neurophysins. Radioactivity was appreciably associated with the undilated parts of neurosecretory axons only during the first few hours after injection of the label. The axonal dilations were subdivided into those in which small vesicles could be seen (“endings”) and those in which no small vesicles could be seen (“swellings”). Radioactivity appeared first in “endings” and then in progressively larger and larger profiles of “swellings”. It appeared that newly arrived granules were found close to the limiting membrane of the nerve swelling and that as time progressed they moved deeper and deeper into the swelling. On the basis of the results, suggestions were made for an anatomical explanation of the readily-releasable pool of hormone which has been demonstrated pharmacologically.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00225108
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  • 3
    Electronic Resource
    Electronic Resource
    Correlations between brain catecholamines, neurosecretion, and serum corticoid levels in osmotically stressed mallard ducks (Anas platyrhynchos) (1975)
    Springer
    Cell & tissue research 161 (1975), S. 277-283 
    Details
    ISSN: 1432-0878
    Keywords: Neurosecretion ; Osmotic stress ; Serum corticoid levels ; Catecholamine depletion ; Anas platyrhynchos (Aves)
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary The effects of depleting brain catecholamines with a combined treatment of reserpine and α-methyl-p-tyrosine on serum corticosterone levels and release of immunoreactive neurophysin from the median eminence, in osmotically stressed and unstressed mallard ducks, were studied. Corticoid levels in salt loaded birds were more than three times that of unstressed birds. The combined treatment of reserpine and α-methyl-p-tyrosine significantly decreased the concentration of brain monoamines in all experimental groups and raised serum corticoid levels in non-stressed birds to the same level found in the osmotically stressed animals. Immunoreactive neurophysin in the zona externa of the median eminence was depleted in all birds subjected to either osmotic stress and/or reserpine treatment but not in unstressed control birds. These preliminary data indicate that catecholamines may exert an inhibitory influence on both ACTH release from the anterior pituitary and neurophysin from the median eminence and that these two events may in some way be interrelated in the duck.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00220374
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  • 4
    Electronic Resource
    Electronic Resource
    The primate median eminence II (1976)
    Springer
    Cell & tissue research 175 (1976), S. 265-277 
    Details
    ISSN: 1432-0878
    Keywords: Median eminence ; Macaca mulatto ; High-voltage electron microscopy ; Neurosecretion ; Ependymal cells
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary The ultrastructure of the normal median eminence of the male rhesus monkey (Macaca mulatta) is described using high-voltage electron microscopy. Surface specializations of ependymal cells lining the infundibular recess included cilia, apical extrusions, and microvilli. Supraependymal cells were predominantly macrophage-like, but examples of lymphocytic types were also seen. Tanycytes had long, branching, basal processes filled with numerous microtubules, some lipid droplets, and granules. The zona interna was composed of large unmyelinated neurosecretory fibers. A few myelinated fibers were also seen, but their character as neurosecretory fibers could not be established. The zona externa was composed of densely-packed profiles of neurosecretory fibers of small diameter, was well-vascularized and contained the terminations of tanycytes. Perivascular glial cells, vesiculated elements, pituicytes, and cellular elements common to connective tissue were observed. The intricate relationships between both the cellular and fibrous elements of the median eminence can be appreciated with the capability of high-voltage electron microscopy to discern ultrastructure in sections 10 times thicker than those used for low-voltage electron microscopy. The median eminence of this primate species has an ultrastructural organization similar to that described for most other species.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00232082
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  • 5
    Electronic Resource
    Electronic Resource
    Distribution of fibres reacting with an α-endorphin antiserum in the neurohypophysis of Carassius auratus and Cyprinus carpio (1978)
    Springer
    Cell & tissue research 189 (1978), S. 251-256 
    Details
    ISSN: 1432-0878
    Keywords: α-Endorphin ; Neurosecretion ; Fish pituitary ; Hypothalamohypophyseal relationships ; Immunocytology
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary A strong positive immunoreaction with an α-endorphin antiserum occurs in two distinct sites of the goldfish and carp neurohypophysis. Fluorescent nerve terminals are found in the laminar nerve processes located in the rostral pars distalis, but the immunocytological reaction is mainly localised on the nerve processes of the posterior neurohypophysis lying between the intermediate lobe cells. Almost all the digitations of the neurohypophysis are strongly fluorescent. The immunoreactive fibres probably originate from the hypothalamus, where perikarya displaying the same immunoreaction have been found in the pars lateralis of the nucleus lateralis tuberis and in some minor centres. The possibility that the immunoreactive substances revealed on the neurohypophyseal processes may originate in the intermediate lobe cells is also discussed. It has now to be established if this hypothalamo-hypophyseal system contains a substance with endorphic properties or only some immunologically related substance devoid of the corresponding physiological activities.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00209274
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  • 6
    Electronic Resource
    Electronic Resource
    Immunofluorescence of somatostatin-producing sites in the hypothalamus of the tadpole, Alytes obstetricans Laur. (1978)
    Springer
    Cell & tissue research 187 (1978), S. 315-321 
    Details
    ISSN: 1432-0878
    Keywords: Hypothalamus ; Tadpole, Alytes obstetricans ; Neurosecretion ; Somatostatin ; Immunofluorescence
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary Three sites of somatostatin-synthesizing perikarya, or a related antigen, were determined by immunofluorescence in the hypothalamus of the tadpole, Alytes obstetricans (Amphibia, Anura). Two sites of neurosecretory perikarya were localized in the preoptic nuclei of the anterior hypothalamus; the axons extended either to the anterior diencephalon or to the median eminence and the pituitary. The third site was found in the posterior hypothalamus. These neurosecretory cells showed a strong immunofluorescent reaction; their axons all terminated at the level of the median eminence. Somatostatin cells were only found in intact or hypophysectomized tadpoles given somatotropin (STH). The strong reaction observed in hypophysectomized tadpoles was possibly due to the loss of the terminal portion of the neurosecretory pathway (median eminence and pituitary) by which the agent is transported to the site of discharge.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00224373
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  • 7
    Electronic Resource
    Electronic Resource
    The ultrastructure of the herring bodies in rats subjected to different experimental conditions (1978)
    Springer
    Cell & tissue research 189 (1978), S. 41-51 
    Details
    ISSN: 1432-0878
    Keywords: Herring bodies (rat) ; Colchicine ; Cold ; Neurosecretion ; Ultrastructure
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary A study of the morphology of Herring bodies of the posterior pituitary lobe of rats treated with colchicine and/or exposed to low temperatures has been performed. After treatment with colchicine (20 μg in distilled water injected intracisternally) a predominance of Herring bodies with a large number of small “synaptic-like” vesicles surrounded by neurosecretory granules is found. Exposures to low temperature (4–6° C) result in an increase in the neurosecretory material and the Herring bodies show many neurosecretory granules of different densities. After treatment with colchicine and subsequent exposure to low temperatures, the Herring bodies are characterized by having a great number of autophagic bodies which become more numerous as the length of the exposure is increased; later autophagic vacuoles and lamellar bodies become evident.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00223120
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  • 8
    Electronic Resource
    Electronic Resource
    Immunocytochemical identification of hyperglycemic hormone-producing cells in the eyestalk of Carcinus maenas (1979)
    Springer
    Cell & tissue research 204 (1979), S. 379-385 
    Details
    ISSN: 1432-0878
    Keywords: Neurosecretion ; Immunofluorescence ; Crustacea ; X-organ ; Hyperglycemic Hormone
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary Antiserum raised in rabbits against extracts of sinus glands from Carcinus and shown by several criteria to contain antibodies directed against the neurosecretory hyperglycemic hormone was used to locate the hormone-producing perikarya in the optic ganglia. By means of the double antibody fluorescence technique, selective staining of the large neurosecretory perikarya of the medulla terminalis ganglionic X-organ (MTGXO) and their axons is obtained. The axon endings of the sinus gland are also stained. None of the other groups of neurosecretory cells in the eyestalk shows fluorescence. Preabsorption of the antiserum with pure hyperglycemic hormone abolishes the fluorescence.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00233650
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  • 9
    Electronic Resource
    Electronic Resource
    The hypothalamo-choroidal tract (1977)
    Springer
    Cell & tissue research 178 (1977), S. 129-141 
    Details
    ISSN: 1432-0878
    Keywords: Choroid plexus ; Vasopressin ; Neurosecretion ; Rat ; Electron microscopy
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary Light and electron microscopic examination of choroid plexuses from lateral ventricles of water-deprived and subcutaneously or intravenously vasopressin administered rats reveal morphologic changes typical for vasopressin responsive fluid transporting epithelia during hormonal stimulation. Ultrastructural changes noted in both dehydrated and vasopressin treated animals included: the frequent occurrence of choroidal “dark” cells, dilatation of the lateral and basal intercellular spaces, increased vacuolization of the apical cytoplasm, and a change in microvillar conformation from the normal clavate type to those with a filiform shape. On the basis of the ultrastructural changes observed it is proposed that the choroid plexus be regarded as a target tissue for vasopressin. These findings indicated that a vasopressinmediated transchoroidal cerebrospinal fluid absorption capability exists.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00232830
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