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  • Springer Nature  (180)
  • Springer  (178)
  • 2020-2022  (257)
  • 1955-1959  (57)
  • 1950-1954  (44)
  • 1
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    Four consecutive yearly point-prevalence studies in Wales indicate lack of improvement in sepsis care on the wards (2021)
    Springer Nature
    Details
    Publication Date: 2021-08-10
    Description: The ‘Sepsis Six’ bundle was promoted as a deliverable tool outside of the critical care settings, but there is very little data available on the progress and change of sepsis care outside the critical care environment in the UK. Our aim was to compare the yearly prevalence, outcome and the Sepsis Six bundle compliance in patients at risk of mortality from sepsis in non-intensive care environments. Patients with a National Early Warning Score (NEWS) of 3 or above and suspected or proven infection were enrolled into four yearly 24-h point prevalence studies, carried out in fourteen hospitals across Wales from 2016 to 2019. We followed up patients to 30 days between 2016–2019 and to 90 days between 2017 and 2019. Out of the 26,947 patients screened 1651 fulfilled inclusion criteria and were recruited. The full ‘Sepsis Six’ care bundle was completed on 223 (14.0%) occasions, with no significant difference between the years. On 190 (11.5%) occasions none of the bundle elements were completed. There was no significant correlation between bundle element compliance, NEWS or year of study. One hundred and seventy (10.7%) patients were seen by critical care outreach; the ‘Sepsis Six’ bundle was completed significantly more often in this group (54/170, 32.0%) than for patients who were not reviewed by critical care outreach (168/1385, 11.6%; p 
    Electronic ISSN: 2045-2322
    Topics: Natural Sciences in General
    Published by Springer Nature
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  • 2
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    A new global ice sheet reconstruction for the past 80 000 years (2021)
    Springer Nature
    In:  EPIC3Nature Communications, Springer Nature, 12(1199), pp. 1-9, ISSN: 2041-1723
    Details
    Publication Date: 2021-07-01
    Description: The evolution of past global ice sheets is highly uncertain. One example is the missing ice problem during the Last Glacial Maximum (LGM, 26 000-19 000 years before present) – an apparent 8-28 m discrepancy between far-field sea level indicators and modelled sea level from ice sheet reconstructions. In the absence of ice sheet reconstructions, researchers often use marine δ 18 O proxy records to infer ice volume prior to the LGM. We present a global ice sheet reconstruction for the past 80 000 years, called PaleoMIST 1.0, constructed inde- pendently of far-field sea level and δ 18 O proxy records. Our reconstruction is compatible with LGM far-field sea-level records without requiring extra ice volume, thus solving the missing ice problem. However, for Marine Isotope Stage 3 (57 000-29 000 years before present) - a pre-LGM period - our reconstruction does not match proxy-based sea level reconstructions, indicating the relationship between marine δ 18 O and sea level may be more complex than assumed.
    Repository Name: EPIC Alfred Wegener Institut
    Type: Article , isiRev
    Format: application/pdf
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  • 3
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    Rebuilding marine life (2020)
    Springer Nature
    In:  EPIC3Nature, Springer Nature, 580(7801), pp. 39-51, ISSN: 0028-0836
    Details
    Publication Date: 2020-06-25
    Description: Sustainable Development Goal 14 of the United Nations aims to “conserve and sustainably use the oceans, seas and marine resources for sustainable development”. Achieving this goal will require rebuilding the marine life-support systems that deliver the many benefits that society receives from a healthy ocean. Here we document the recovery of marine populations, habitats and ecosystems following past conservation interventions. Recovery rates across studies suggest that substantial recovery of the abundance, structure and function of marine life could be achieved by 2050, if major pressures—including climate change—are mitigated. Rebuilding marine life represents a doable Grand Challenge for humanity, an ethical obligation and a smart economic objective to achieve a sustainable future.
    Repository Name: EPIC Alfred Wegener Institut
    Type: Article , peerRev
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  • 4
    Electronic Resource
    Electronic Resource
    On the adiabatic Couette flow of a compressible fluid (1957)
    Springer
    Zeitschrift für angewandte Mathematik und Physik 8 (1957), S. 89-96 
    Details
    ISSN: 1420-9039
    Source: Springer Online Journal Archives 1860-2000
    Topics: Mathematics , Physics
    Notes: Zusammenfassung Eine Untersuchung wurde durchgeführt über die adiabatische Strömung der Luft zwischen zwei parallelen Platten, bei einem Druckunterschied quer über die sich bewegende Platte. Die Lösung lässt eine thermale Keilwirkung der hydrodynamischen Schmierung erwarten und gibt eine quantitative Analyse des allgemeineren Problems, wo ein Druckunterschied quer über die Gleitplatte vorhanden ist. Die Ergebnisse deuten an, dass der Beitrag des hydrodynamischen Druckes oft äusserst klein sein kann (für mässige Geschwindigkeiten) im Vergleich zum hydrodynamischen Druck in den dem Druck ausgesetzten Lagern. Im Falle von stillstehenden Platten ist die adiabatische Lösung gleich der isothermen Lösung; weswegen keine Temperaturerhöhung stattfindet.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01590606
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  • 5
    Electronic Resource
    Electronic Resource
    Anxiety and learning in rats under stress-avoidance-discrimination conditions as influenced by chlorpromazine, reserpine, and glutamate (1958)
    Springer
    Cellular and molecular life sciences 14 (1958), S. 301-302 
    Details
    ISSN: 1420-9071
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Zusammenfassung Ein neuer Apparat wird beschrieben, in welchem die Wirkungen von Chlorpromazin, Reserpin und Natriumglutamat auf Furcht und Lernen in Ratten untersucht wurden.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02167014
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  • 6
    Electronic Resource
    Electronic Resource
    Serotonin storage mechanism and its interaction with reserpine (1958)
    Springer
    Cellular and molecular life sciences 14 (1958), S. 178-180 
    Details
    ISSN: 1420-9071
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Zusammenfassung Es gelang nicht, mit physikalisch-chemischen Methoden einen HT-Komplex in hämolysierten oder homogenisierten Suspensionen von Kaninchen-Thrombozyten nachzuweisen. Versuchsergebnisse über die HT-Aufnahme durch Thrombozyten stimmen mit der Möglichkeit überein, dass das Amin in den Zellen durch einen aktiven Transportmechanismus konzentriert wird. Es wird angenommen, dass die Abgabe von normalem HT aus der Zelle unter Reserpineinwirkung, durch eine Hemmung des Aufnahmemechanismus und langsame, passive Diffusion aus den Zellen erfolgt.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02158651
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  • 7
    Electronic Resource
    Electronic Resource
    The chromosomes of mantids (Orthoptera: manteidae) in relation to taxonomy (1950)
    Springer
    Chromosoma 4 (1950), S. 1-55 
    Details
    ISSN: 1432-0886
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary The distinguishing cytological characters, including chromosome number and sex chromosome mechanism, have been tabulated for all mantids thus far studied cytologically—including 16 species (starred in Table 1) not hitherto examined. Data on 46 species in 17 subfamilies are reviewed. The XO♂—XX ♀ sex chromosome mechanism represents the ancestral condition for the family and has been retained in 14 of the subfamilies sampled. The distribution of the X1X2Y♂—X1X1X2X2♀ mechanism, previously known in the subfamilies Manteinae and Choeradodinae, is extended to include Mellierinae, Acromantinae and Vatinae. Cytological evidence indicates a monophyletic origin of the compound sex chromosomes and necessitates a reconsideration of the taxonomic association of XO and X1X2Y forms in the same subfamily, specifically of Miomantis and Callimantis with the other Manteinae, and Aethalocroa with Vates and Phyllovates in the Vatinae. The pre-metaphase stretch is established as a regular stage in male meiosis in 14—and is absent in 3—of the species checked for this character. It should prove of taxonomic value when a wider sampling of the lower categories is available. The prolongation of parallel pairing of homologous chromosomes in male meiosis appears to be characteristic of the Manteidae as a whole. No correlation is apparent between the degree of its expression and taxonomic category. Since it provides a mechanism, additional or alternative to chiasmata, for the post-pachytene association of homologues, its establishment permits the evolution of non-chiasmate meiosis in the group. Two structural types of bivalents—one with, one without chiasmata—are found. Present evidence favors the multiple origin of the non-chiasmate type within the family, and since both types may coexist in the karyotype of the same sex of a single species, presence or absence of chiasmata cannot be considered a valid taxonomic criterion.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00325766
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  • 8
    Electronic Resource
    Electronic Resource
    Polyteny as a factor in the chromosomal evolution of the pentatomini (Hemiptera) (1956)
    Springer
    Chromosoma 8 (1956), S. 135-151 
    Details
    ISSN: 1432-0886
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary 1. ThePentatomini, which constitute a single Tribe within one of the Subfamilies of the hemipteran FamilyPentatomidae, include an unusually large number of species. Though these species vary considerably in their size and color, they are very uniform in their essential external and internal morphology. 2. Uniformity also characterizes such features in the Tribe as the chromosome number and meiotic behavior. But in the eleven species here investigated, this uniformity does not extend to the DNA content of the male meiotic cells, as determined by Feulgen cytophotometry. 3. The lowest DNA content is found inThyanta which, in this respect, is well separated from an intermediate group whose DNA values vary around a mean that is roughly double the lowest amount. Some evidence is available that a still higher multiple of DNA may be represented in theAcrosternum-Nezara complex of species. 4. In view of these cytochemical data, the multiplicity of species coupled with a striking uniformity of morphological and cytological features is provisionally explained on the basis of varying polyteny.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01259497
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  • 9
    Electronic Resource
    Electronic Resource
    On the cytotaxonomy of phasmids (Phasmatodea) (1959)
    Springer
    Chromosoma 10 (1959), S. 268-277 
    Details
    ISSN: 1432-0886
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary A wide diversity in chromosome complement is found in two species of phasmids of the primitive group Prisopini—Prisopus ariadne Hebard and Prisopus berosus Westwood. P. ariadne has a diploid male complement of 28, comprising 13 pairs of relatively large mediokinetic autosomes and Neo XY sex chromosomes. P. berosus, 2n ♂=49, has relatively small autosomes most of which are mediokinetic, and retains the XO—XX sex mechanism. Chromosomal polymorphism in this species is suggested by the presence of an unequal pair of autosomes and a structural differentiation in the X in one of two males studied. The relative amount of DNA per nucleus in male germ cells (Peulgen cytophotometry) shows a significant difference in total chromosomal content between the complements of the two species. These data are discussed with reference to the cytotaxonomy of phasmids.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00396574
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  • 10
    Electronic Resource
    Electronic Resource
    The “pre-metaphase stretch” and kinetochore orientation in phasmids (1950)
    Springer
    Chromosoma 3 (1950), S. 1-21 
    Details
    ISSN: 1432-0886
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary 1. The pre-metaphase stretch is found to be a normal stage in male meiosis in six species of phasmids. 2. Its essential features are a precocious orientation of the kinetochores and their movement toward opposite poles of the developing spindle in first meiotic prophase, — with a consequent stretching of the chromosomes. It is followed by recontraction of the chromosomes and their movement to the equator. Attraction beween kinetochore and center, reinforced by the effect of elongation of the spindle, is considered responsible for the movements of the stretch. 3. The pre-metaphase stretch in phasmids differs from that of mantids in (1) its timing relative to meiotic stage, and (2) its expression in one species in the prophase of both meiotic divisions. 4. The distribution of the stretch in nature, and its significance for the mechanism of mitosis are discussed.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00319466
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