ALBERT

All Library Books, journals and Electronic Records Telegrafenberg

feed icon rss

Your email was sent successfully. Check your inbox.

An error occurred while sending the email. Please try again.

Proceed reservation?

Export
Filter
  • 2020-2022  (11)
  • 2005-2009  (204)
  • 1985-1989  (80)
Collection
Years
Year
  • 1
    Publication Date: 1989-01-13
    Description: The chemical synthesis of biologically active peptides and polypeptides can be achieved by using a convergent strategy of condensing protected peptide segments to form the desired molecule. An oxime support increases the ease with which intermediate protected peptides can be synthesized and makes this approach useful for the synthesis of peptides in which secondary structural elements have been redesigned. The extension of these methods to large peptides and proteins, for which folding of secondary structures into functional tertiary structures is critical, is discussed. Models of apolipoproteins, the homeo domain from the developmental protein encoded by the Antennapedia gene of Drosophila, a part of the Cro repressor, and the enzyme ribonuclease T1 and a structural analog have been synthesized with this method.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Kaiser, E T -- Mihara, H -- Laforet, G A -- Kelly, J W -- Walters, L -- Findeis, M A -- Sasaki, T -- DK07825/DK/NIDDK NIH HHS/ -- GM12054/GM/NIGMS NIH HHS/ -- HL-186577/HL/NHLBI NIH HHS/ -- New York, N.Y. -- Science. 1989 Jan 13;243(4888):187-92.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Laboratory of Bioorganic Chemistry and Biochemistry, Rockefeller University, New York, NY 10021.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/2492114" target="_blank"〉PubMed〈/a〉
    Keywords: Amino Acid Sequence ; Apolipoprotein A-I ; Apolipoproteins A/chemical synthesis ; Humans ; Indicators and Reagents ; Lipoproteins, HDL/chemical synthesis ; Peptides/*chemical synthesis ; Protein Conformation ; Proteins/*chemical synthesis
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
  • 2
    Publication Date: 2009-01-30
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Sasaki, Takuji -- Antonio, Baltazar A -- England -- Nature. 2009 Jan 29;457(7229):547-8. doi: 10.1038/457547a.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/19177121" target="_blank"〉PubMed〈/a〉
    Keywords: Crops, Agricultural/genetics ; Genome, Plant/*genetics ; Genomics ; Sequence Analysis, DNA ; Sorghum/*genetics
    Print ISSN: 0028-0836
    Electronic ISSN: 1476-4687
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
  • 3
    Publication Date: 2006-10-21
    Description: The intensity of Galactic cosmic rays is nearly isotropic because of the influence of magnetic fields in the Milky Way. Here, we present two-dimensional high-precision anisotropy measurement for energies from a few to several hundred teraelectronvolts (TeV), using the large data sample of the Tibet Air Shower Arrays. Besides revealing finer details of the known anisotropies, a new component of Galactic cosmic ray anisotropy in sidereal time is uncovered around the Cygnus region direction. For cosmic-ray energies up to a few hundred TeV, all components of anisotropies fade away, showing a corotation of Galactic cosmic rays with the local Galactic magnetic environment. These results have broad implications for a comprehensive understanding of cosmic rays, supernovae, magnetic fields, and heliospheric and Galactic dynamic environments.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Amenomori, M -- Ayabe, S -- Bi, X J -- Chen, D -- Cui, S W -- Danzengluobu -- Ding, L K -- Ding, X H -- Feng, C F -- Feng, Zhaoyang -- Feng, Z Y -- Gao, X Y -- Geng, Q X -- Guo, H W -- He, H H -- He, M -- Hibino, K -- Hotta, N -- Hu, Haibing -- Hu, H B -- Huang, J -- Huang, Q -- Jia, H Y -- Kajino, F -- Kasahara, K -- Katayose, Y -- Kato, C -- Kawata, K -- Labaciren -- Le, G M -- Li, A F -- Li, J Y -- Lou, Y-Q -- Lu, H -- Lu, S L -- Meng, X R -- Mizutani, K -- Mu, J -- Munakata, K -- Nagai, A -- Nanjo, H -- Nishizawa, M -- Ohnishi, M -- Ohta, I -- Onuma, H -- Ouchi, T -- Ozawa, S -- Ren, J R -- Saito, T -- Saito, T Y -- Sakata, M -- Sako, T K -- Sasaki, T -- Shibata, M -- Shiomi, A -- Shirai, T -- Sugimoto, H -- Takita, M -- Tan, Y H -- Tateyama, N -- Torii, S -- Tsuchiya, H -- Udo, S -- Wang, B -- Wang, H -- Wang, X -- Wang, Y G -- Wu, H R -- Xue, L -- Yamamoto, Y -- Yan, C T -- Yang, X C -- Yasue, S -- Ye, Z H -- Yu, G C -- Yuan, A F -- Yuda, T -- Zhang, H M -- Zhang, J L -- Zhang, N J -- Zhang, X Y -- Zhang, Y -- Zhang, Yi -- Zhaxisangzhu -- Zhou, X X -- Tibet ASgamma Collaboration -- New York, N.Y. -- Science. 2006 Oct 20;314(5798):439-43.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Department of Physics, Hirosaki University, Hirosaki 036-8561, Japan.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/17053141" target="_blank"〉PubMed〈/a〉
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
  • 4
    Publication Date: 2008-02-02
    Description: Core-collapse supernovae (CC-SNe) are the explosions that announce the death of massive stars. Some CC-SNe are linked to long-duration gamma-ray bursts (GRBs) and are highly aspherical. One important question is to what extent asphericity is common to all CC-SNe. Here we present late-time spectra for a number of CC-SNe from stripped-envelope stars and use them to explore any asphericity generated in the inner part of the exploding star, near the site of collapse. A range of oxygen emission-line profiles is observed, including a high incidence of double-peaked profiles, a distinct signature of an aspherical explosion. Our results suggest that all CC-SNe from stripped-envelope stars are aspherical explosions and that SNe accompanied by GRBs exhibit the highest degree of asphericity.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Maeda, Keiichi -- Kawabata, Koji -- Mazzali, Paolo A -- Tanaka, Masaomi -- Valenti, Stefano -- Nomoto, Ken'ichi -- Hattori, Takashi -- Deng, Jinsong -- Pian, Elena -- Taubenberger, Stefan -- Iye, Masanori -- Matheson, Thomas -- Filippenko, Alexei V -- Aoki, Kentaro -- Kosugi, George -- Ohyama, Youichi -- Sasaki, Toshiyuki -- Takata, Tadafumi -- New York, N.Y. -- Science. 2008 Feb 29;319(5867):1220-3. doi: 10.1126/science.1149437. Epub 2008 Jan 31.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Institute for the Physics and Mathematics of the Universe (IPMU), University of Tokyo, Kashiwa-no-ha 5-1-5, Kashiwa City, Chiba 277-8582, Japan. maeda@ea.c.u-tokyo.ac.jp〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/18239091" target="_blank"〉PubMed〈/a〉
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
  • 5
    Publication Date: 2006-04-15
    Description: Loss of seed shattering was a key event in the domestication of major cereals. We revealed that the qSH1 gene, a major quantitative trait locus of seed shattering in rice, encodes a BEL1-type homeobox gene and demonstrated that a single-nucleotide polymorphism (SNP) in the 5' regulatory region of the qSH1 gene caused loss of seed shattering owing to the absence of abscission layer formation. Haplotype analysis and association analysis in various rice collections revealed that the SNP was highly associated with shattering among japonica subspecies of rice, implying that it was a target of artificial selection during rice domestication.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Konishi, Saeko -- Izawa, Takeshi -- Lin, Shao Yang -- Ebana, Kaworu -- Fukuta, Yoshimichi -- Sasaki, Takuji -- Yano, Masahiro -- New York, N.Y. -- Science. 2006 Jun 2;312(5778):1392-6. Epub 2006 Apr 13.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Institute of the Society for Techno-Innovation of Agriculture, Forestry, and Fisheries, 446-1 Ippaizuka, Kamiyokoba Tsukuba, Ibaraki 305-0854, Japan.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/16614172" target="_blank"〉PubMed〈/a〉
    Keywords: Agriculture/*history ; Alleles ; Chromosome Mapping ; Chromosomes, Plant ; Crops, Agricultural/*genetics/history ; Genes, Plant ; History, Ancient ; Humans ; Molecular Sequence Data ; Oryza/*genetics/history ; Plant Proteins/genetics ; *Polymorphism, Single Nucleotide ; Quantitative Trait Loci ; *Seeds ; Transcription Factors/genetics
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
  • 6
    Publication Date: 2009-03-28
    Description: During chemotaxis, activation of the small guanosine triphosphatase Rac is spatially regulated to organize the extension of membrane protrusions in the direction of migration. In neutrophils, Rac activation is primarily mediated by DOCK2, an atypical guanine nucleotide exchange factor. Upon stimulation, we found that DOCK2 rapidly translocated to the plasma membrane in a phosphatidylinositol 3,4,5-trisphosphate-dependent manner. However, subsequent accumulation of DOCK2 at the leading edge required phospholipase D-mediated synthesis of phosphatidic acid, which stabilized DOCK2 there by means of interaction with a polybasic amino acid cluster, resulting in increased local actin polymerization. When this interaction was blocked, neutrophils failed to form leading edges properly and exhibited defects in chemotaxis. Thus, intracellular DOCK2 dynamics are sequentially regulated by distinct phospholipids to localize Rac activation during neutrophil chemotaxis.〈br /〉〈br /〉〈a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3761877/" target="_blank"〉〈img src="https://static.pubmed.gov/portal/portal3rc.fcgi/4089621/img/3977009" border="0"〉〈/a〉   〈a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3761877/" target="_blank"〉This paper as free author manuscript - peer-reviewed and accepted for publication〈/a〉〈br /〉〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Nishikimi, Akihiko -- Fukuhara, Hideo -- Su, Wenjuan -- Hongu, Tsunaki -- Takasuga, Shunsuke -- Mihara, Hisashi -- Cao, Qinhong -- Sanematsu, Fumiyuki -- Kanai, Motomu -- Hasegawa, Hiroshi -- Tanaka, Yoshihiko -- Shibasaki, Masakatsu -- Kanaho, Yasunori -- Sasaki, Takehiko -- Frohman, Michael A -- Fukui, Yoshinori -- R01 GM084251/GM/NIGMS NIH HHS/ -- R01GM71520/GM/NIGMS NIH HHS/ -- New York, N.Y. -- Science. 2009 Apr 17;324(5925):384-7. doi: 10.1126/science.1170179. Epub 2009 Mar 26.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Division of Immunogenetics, Department of Immunobiology and Neuroscience, Medical Institute of Bioregulation, Kyushu University, Fukuoka 812-8582, Japan.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/19325080" target="_blank"〉PubMed〈/a〉
    Keywords: 1-Butanol/pharmacology ; Actins/metabolism ; Animals ; Cell Line ; Cell Membrane/*metabolism ; Cell Polarity ; *Chemotaxis, Leukocyte ; Enzyme Inhibitors/pharmacology ; GTPase-Activating Proteins/chemistry/genetics/*metabolism ; Humans ; Mice ; Neutrophils/cytology/drug effects/*physiology ; Phosphatidic Acids/*metabolism/pharmacology ; Phosphatidylinositol Phosphates/*metabolism ; Phospholipase D/genetics/metabolism ; Protein Binding ; Pseudopodia/metabolism ; Recombinant Fusion Proteins/metabolism ; Signal Transduction ; rac GTP-Binding Proteins/metabolism
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
  • 7
    Electronic Resource
    Electronic Resource
    Woodbury, NY : American Institute of Physics (AIP)
    Applied Physics Letters 53 (1988), S. 1-3 
    ISSN: 1077-3118
    Source: AIP Digital Archive
    Topics: Physics
    Notes: Lasing characteristics have been investigated systematically in long-wavelength InGaAs separate confinement heterostructure quantum well laser diodes (SCH QW LD's) with varied well thicknesses and number of wells, for the first time. Marked improvements in threshold current density and characteristic temperature values have been observed in SCH MQW LD's to SCH SQW LD's. Maximum cw output power of 46 mW at 20 °C has been achieved in SCH QW LD's with five wells, which is the highest among the long-wavelength quantum well LD's.
    Type of Medium: Electronic Resource
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
  • 8
    ISSN: 1077-3118
    Source: AIP Digital Archive
    Topics: Physics
    Notes: We obtained damage-resistant crystals of potassium dihydrogen phosphate (KDP) by reducing organic impurities in the growth solution. To prevent organic impurity exuded from the wall of the growth vessel, Pyrex glass was used. The residual organic impurities, which mainly derived from KDP raw powder, were reduced by photochemical dissociation using a combination of ultraviolet light and an oxidant (hydrogen peroxide). The resultant total organic carbon of the solution was less than 0.1 ppm. The damage threshold of the crystals grown from this solution was always high (20–22 J/cm2), which is about three times higher than that of crystals grown by conventional methods.
    Type of Medium: Electronic Resource
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
  • 9
    Electronic Resource
    Electronic Resource
    [S.l.] : American Institute of Physics (AIP)
    Journal of Applied Physics 64 (1988), S. 4531-4535 
    ISSN: 1089-7550
    Source: AIP Digital Archive
    Topics: Physics
    Notes: Single-crystal gallium nitride was grown on each of the two polar {0001} planes of 6H-silicon carbide substrates utilizing metal-organic vapor-phase epitaxy. The substrate polarity is clearly shown to strongly influence the surface morphology and the photoluminescence property of the layer. The examination of the layer surfaces using x-ray photoelectron spectroscopy revealed that {0001} GaN grown on the basal planes of SiC changes its polarity in accordance with the substrate polarity.
    Type of Medium: Electronic Resource
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
  • 10
    ISSN: 1089-7550
    Source: AIP Digital Archive
    Topics: Physics
    Notes: The chromogenic limulus test has been applied for the first time to detect an organic impurity contained in potassium dihydrogen phosphate (KDP) crystals. Impurities arise from microbes present during crystal growth, and are responsible for a reduced laser damage threshold. A sensitivity of 10 pg/g KDP (10−5 ppm) was achieved, provided that the KDP solution was neutralized to ∼pH 7. Endotoxin content in the prismatic region of KDP crystals grown in a microbe-rich solution was approximately 100 pg/g KDP. The presence of an organic material in seemingly perfect KDP crystals could be experimentally confirmed.
    Type of Medium: Electronic Resource
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
Close ⊗
This website uses cookies and the analysis tool Matomo. More information can be found here...