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  • Chemistry  (2)
  • Dendritic cells  (1)
  • 2020-2021
  • 1990-1994  (1)
  • 1970-1974
  • 1950-1954  (2)
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Publisher
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  • 2020-2021
  • 1990-1994  (1)
  • 1970-1974
  • 1950-1954  (2)
  • 1955-1959  (2)
Year
  • 1
    ISSN: 1432-0878
    Keywords: Antigen-presenting cells ; Major histocompatibility complex class II (MHC class II) ; Macrophages ; Dendritic cells ; Meninges ; Dorsal root ganglia ; Spihal cord ; Rat (Wistar, SIV, Brown-Norway: Ch. Rivcr Wiga)
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Abstract This report deals with the distribution, morphology and specific topical relationships of bone-marrow-derived cells (free cells) in the spinal meninges and dorsal root ganglia of the normal rat. The morphology of these cells has been studied by transmission and scanning electron microscopy. Cells expressing the major histocompatibility complex (MHC) class II gene product have been recognized by immunofluorescence. At the level of the transmission electron microscope, free cells are found in all layers of the meninges. Many of them display characteristic ultrastructural features of macrophages, whereas others show a highly vacuolated cytoplasm and are endowed with many processes. These elements lack a conspicuous lysosomal system and might represent dendritic cells. Scanning electron microscopy has revealed that free cells contact the cerebrospinal fluid via abundant cytoplasmic processes that cross the cell layers of the pia mater and of the arachnoid. Cells expressing the MHC class II antigen are also found in all layers of the meninges. They are particularly abundant in the layers immediately adjacent to the subarachnoid space, in the neighbourhood of dural vessels, along the spinal roots and in the dural funnels. In addition to the meninges, strong immunoreactivity for MHC class II antigen is observed in the dorsal root ganglia. The ultrastructural and immunohistochemical findings of this study suggest the existence of a well-developed system of immunological surveillance of the subarachnoid space and of the dorsal root ganglia.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    New York, NY : Wiley-Blackwell
    Helvetica Chimica Acta 37 (1954), S. 1805-1814 
    ISSN: 0018-019X
    Keywords: Chemistry ; Organic Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Notes: L'aricine C22H26O4N2 conduit par déshydrogénation sélénique à un produit dont la majeure partie possède la structure d'une méthoxydéséthyl-alstyrine (VIb) (démontrée par désintégration et identité des produits dérivés avec ceux préparés par synthèse).
    Additional Material: 3 Ill.
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    New York, NY : Wiley-Blackwell
    Helvetica Chimica Acta 37 (1954), S. 2161-2165 
    ISSN: 0018-019X
    Keywords: Chemistry ; Organic Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Notes: Isorauhimbin, C21H26O3N2, ein mit Yohimbin isomeres Alkaloid aus den Wurzeln von Rauwolfia serpentina Benth., lieferte bei der Dehydrierung mit Selen Yobyrin, Tetrabyrin und Dehydro-keto-yobyrin. Daraus lässt sich ableiten, dass Isorauhimbin das gleiche Ringgerüst wie Yohimbin aufweist, und dass die Methoxycarbonyl-Gruppe ebenfalls am Kohlenstoffatom 16 sitzt. Die Stellung der Hydroxylgruppe, deren sekundärer Charakter durch Acetylierung nachgewiesen wurde, bleibt noch ungewiss, da die Oxydation nach Oppenauer bisher zu keinem kristallisierten Abbauprodukt führte.
    Additional Material: 3 Ill.
    Type of Medium: Electronic Resource
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